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- Publisher
- Springer Journals
- Copyright
- Copyright © 1995 by Springer-Verlag New York Inc
- Subject
- Life Sciences; Evolutionary Biology; Microbiology; Plant Sciences; Plant Genetics and Genomics; Animal Genetics and Genomics; Cell Biology
- ISSN
- 0022-2844
- eISSN
- 1432-1432
- DOI
- 10.1007/BF00175816
- Publisher site
- See Article on Publisher Site
Abstract
A correspondence between open reading frames in sense and antisense strands is expected from the hypothesis that the prototypic triplet code was of general form RNY, where R is a purine base, N is any base, and Y is a pyrimidine. A deficit of stop codons in the antisense strand (and thus long open reading frames) is predicted for organisms with high G + C percentages; however, two bacteria (Azotobacter vinelandii, Rhodobacter capsulatum) have larger average antisense strand open reading frames than predicted from (G + C)%. The similar Codon frequencies found in sense and antisense strands can be attributed to the wide distribution of inverted repeats (stem-loop potential) in natural DNA sequences.
Journal
Journal of Molecular Evolution – Springer Journals
Published: Jul 5, 2004