/lp/taylor-francis/damage-of-dna-and-proteins-by-major-lipid-peroxidation-products-in-8Vcwpse5lj
References (164)
-
Tobias Jung, M. Engels, Barbara Kaiser, T. Grune (2005)
Distribution of oxidized and HNE‐modified proteins in U87 cellsBioFactors, 24
-
A. Bellacosa (2001)
Role of MED1 (MBD4) Gene in DNA repair and human cancerJournal of Cellular Physiology, 187
-
S. Langouët, Adrienne Mican, Michael Müller, S. Fink, L. Marnett, S. Muhle, F. Guengerich (1998)
Misincorporation of nucleotides opposite five-membered exocyclic ring guanine derivatives by escherichia coli polymerases in vitro and in vivo: 1,N2-ethenoguanine, 5,6,7,9-tetrahydro-9-oxoimidazo[1, 2-a]purine, and 5,6,7,9-tetrahydro-7-hydroxy-9-oxoimidazo[1, 2-a]purine.Biochemistry, 37 15
-
P. Fernandes, Hao Wang, C. Rizzo, R. Lloyd (2003)
Site‐specific mutagenicity of stereochemically defined 1,N2‐deoxyguanosine adducts of trans‐4‐hydroxynonenal in mammalian cellsEnvironmental and Molecular Mutagenesis, 42
-
J. Nair, G. Fürstenberger, F. Bürger, F. Marks, H. Bartsch (2000)
Promutagenic etheno-DNA adducts in multistage mouse skin carcinogenesis: correlation with lipoxygenase-catalyzed arachidonic acid metabolism.Chemical research in toxicology, 13 8
-
Hai Huang, Hao Wang, Albena Kozekova, C. Rizzo, M. Stone (2011)
Formation of a N2-dG:N2-dG Carbinolamine DNA Cross-link by the trans-4-Hydroxynonenal-Derived (6S,8R,11S) 1,N2-dG AdductJournal of the American Chemical Society, 133
-
M. Yoo, X. Gu, Xue-ming Xu, Jin-Young Kim, B. Carlson, A. Patterson, H. Cai, V. Gladyshev, D. Hatfield (2010)
Delineating the role of glutathione peroxidase 4 in protecting cells against lipid hydroperoxide damage and in Alzheimer's disease.Antioxidants & redox signaling, 12 7
-
J. West, L. Marnett (2005)
Alterations in gene expression induced by the lipid peroxidation product, 4-hydroxy-2-nonenal.Chemical research in toxicology, 18 11
-
S. Pizzimenti, Federica Briatore, Stefano Laurora, C. Toaldo, M. Maggio, M. Grandi, Laura Meaglia, E. Menegatti, B. Giglioni, M. Dianzani, G. Barrera (2006)
4-Hydroxynonenal inhibits telomerase activity and hTERT expression in human leukemic cell lines.Free radical biology & medicine, 40 9
-
G. Robino, M. Parola, F. Marra, A. Caligiuri, R. Franco, E. Zamara, G. Bellomo, P. Gentilini, M. Pinzani, M. Dianzani (2000)
Interaction between 4-hydroxy-2,3-alkenals and the platelet-derived growth factor-beta receptor. Reduced tyrosine phosphorylation and downstream signaling in hepatic stellate cells.The Journal of biological chemistry, 275 51
-
M. Moriya, W. Zhang, F. Johnson, A. Grollman (1994)
Mutagenic potency of exocyclic DNA adducts: marked differences between Escherichia coli and simian kidney cells.Proceedings of the National Academy of Sciences of the United States of America, 91 25
-
Vibeke Leihne, F. Kirpekar, C. Vågbø, E. Born, H. Krokan, P. Grini, Trine Meza, P. Falnes (2011)
Roles of Trm9- and ALKBH8-like proteins in the formation of modified wobble uridines in Arabidopsis tRNANucleic Acids Research, 39
-
M. Valko, D. Leibfritz, J. Moncol’, M. Cronin, M. Mazúr, J. Telser (2007)
Free radicals and antioxidants in normal physiological functions and human disease.The international journal of biochemistry & cell biology, 39 1
-
F. Vieira, P. Pietro, B. Boaventura, Claudia Ambrosi, G. Rockenbach, M. Fausto, C. Crippa, E. Silva (2011)
Factors associated with oxidative stress in women with breast cancer.Nutricion hospitalaria, 26 3
-
L. Marnett (1999)
Lipid peroxidation-DNA damage by malondialdehyde.Mutation research, 424 1-2
-
A. Federico, F. Morgillo, C. Tuccillo, F. Ciardiello, C. Loguercio (2007)
Chronic inflammation and oxidative stress in human carcinogenesisInternational Journal of Cancer, 121
-
R. Ougland, Chun-mei Zhang, A. Liiv, R. Johansen, E. Seeberg, Ya-Ming Hou, J. Remme, P. Falnes (2004)
AlkB restores the biological function of mRNA and tRNA inactivated by chemical methylation.Molecular cell, 16 1
-
V. Palejwala, D. Simha, M. Humayun (1991)
Mechanisms of mutagenesis by exocyclic DNA adducts. Transfection of M13 viral DNA bearing a site-specific adduct shows that ethenocytosine is a highly efficient RecA-independent mutagenic noninstructional lesion.Biochemistry, 30 36
-
S. Pizzimenti, E. Menegatti, D. Berardi, C. Toaldo, P. Pettazzoni, R. Minelli, B. Giglioni, A. Cerbone, M. Dianzani, C. Ferretti, G. Barrera (2010)
4-hydroxynonenal, a lipid peroxidation product of dietary polyunsaturated fatty acids, has anticarcinogenic properties in colon carcinoma cell lines through the inhibition of telomerase activity.The Journal of nutritional biochemistry, 21 9
-
Karen Schmid, J. Nair, G. Winde, I. Velic, H. Bartsch (2000)
Increased levels of promutagenic etheno‐dna adducts in colonic polyps of FAP patientsInternational Journal of Cancer, 87
-
J. Ringvoll, Line Nordstrand, C. Vågbø, V. Talstad, K. Reite, P. Aas, Knut Lauritzen, N. Liabakk, A. Bjørk, R. Doughty, P. Falnes, H. Krokan, A. Klungland (2006)
Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNAThe EMBO Journal, 25
-
A. Maciejewska, K. Ruszel, J. Nieminuszczy, Joanna Lewicka, B. Sokołowska, E. Grzesiuk, J. Kuśmierek (2010)
Chloroacetaldehyde-induced mutagenesis in Escherichia coli: the role of AlkB protein in repair of 3,N(4)-ethenocytosine and 3,N(4)-alpha-hydroxyethanocytosine.Mutation research, 684 1-2
-
Keith Cheng, B. Preston, David Cahill, M. Dosanjh, B. Singer, L. Loeb (1991)
The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli.Proceedings of the National Academy of Sciences of the United States of America, 88 22
-
Y. Mishina, Cai-Guang Yang, Chuan He (2005)
Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins.Journal of the American Chemical Society, 127 42
-
P. Koivisto, T. Duncan, T. Lindahl, B. Sedgwick (2003)
Minimal Methylated Substrate and Extended Substrate Range of Escherichia coli AlkB Protein, a 1-Methyladenine-DNA Dioxygenase*Journal of Biological Chemistry, 278
-
Dragony Fu, L. Samson (2012)
Direct repair of 3,N(4)-ethenocytosine by the human ALKBH2 dioxygenase is blocked by the AAG/MPG glycosylase.DNA repair, 11 1
-
K. Shimada, Mitsutoshi Nakamura, E. Ishida, T. Higuchi, Hiroshi Yamamoto, K. Tsujikawa, N. Konishi (2007)
Prostate cancer antigen‐1 contributes to cell survival and invasion though discoidin receptor 1 in human prostate cancerCancer Science, 99
-
Bo Pang, Xinfeng Zhou, Hongbin Yu, M. Dong, K. Taghizadeh, J. Wishnok, S. Tannenbaum, P. Dedon (2007)
Lipid peroxidation dominates the chemistry of DNA adduct formation in a mouse model of inflammation.Carcinogenesis, 28 8
-
M. Valko, C. Rhodes, J. Moncol’, Mário Izakovič, M. Mazúr (2006)
Free radicals, metals and antioxidants in oxidative stress-induced cancer.Chemico-biological interactions, 160 1
-
V. Katalinić, I. Salamunić, S. Pažanin, R. Mulić, M. Milisić, D. Ropac (2007)
The antioxidant power and level of lipid peroxidation products in the sera of apparently healthy adult males.Collegium antropologicum, 31 1
-
Wei Liu, A. Akhand, M. Kato, I. Yokoyama, T. Miyata, K. Kurokawa, K. Uchida, I. Nakashima (1999)
4-hydroxynonenal triggers an epidermal growth factor receptor-linked signal pathway for growth inhibition.Journal of cell science, 112 ( Pt 14)
-
T. Grune, K. Davies (2003)
The proteasomal system and HNE-modified proteins.Molecular aspects of medicine, 24 4-5
-
(2009)
DNA repair in mammalian cells: Direct DNA damage reversal: elegant solutions for nasty problems, 66
-
H. Bartsch, J. Nair (2005)
Accumulation of lipid peroxidation-derived DNA lesions: potential lead markers for chemoprevention of inflammation-driven malignancies.Mutation research, 591 1-2
-
K. Uchida, Mihoko Shiraishi, Y. Naito, Y. Torii, Yoshimasa Nakamura, T. Osawa (1999)
Activation of Stress Signaling Pathways by the End Product of Lipid PeroxidationThe Journal of Biological Chemistry, 274
-
B. Sedgwick, P. Bates, Johanna Paik, Susan Jacobs, T. Lindahl (2007)
Repair of alkylated DNA: recent advances.DNA repair, 6 4
-
E. Speina, M. Zielińska, A. Barbin, D. Gackowski, J. Kowalewski, M. Graziewicz, J. Siedlecki, R. Olinski, B. Tudek (2003)
Decreased repair activities of 1,N(6)-ethenoadenine and 3,N(4)-ethenocytosine in lung adenocarcinoma patients.Cancer research, 63 15
-
A unifi ed view of base excision repair -
P. Fortini, E. Dogliotti (2007)
Base damage and single-strand break repair: mechanisms and functional significance of short- and long-patch repair subpathways.DNA repair, 6 4
-
M. Westbye, Emadoldin Feyzi, P. Aas, C. Vågbø, V. Talstad, B. Kavli, Lars Hagen, O. Sundheim, M. Akbari, N. Liabakk, G. Slupphaug, M. Otterlei, H. Krokan (2008)
Human AlkB Homolog 1 Is a Mitochondrial Protein That Demethylates 3-Methylcytosine in DNA and RNA*Journal of Biological Chemistry, 283
-
C. Yi, Cai-Guang Yang, Chuan He (2009)
A non-heme iron-mediated chemical demethylation in DNA and RNA.Accounts of chemical research, 42 4
-
Seon-Hwa Lee, J. Arora, T. Oe, I. Blair (2005)
4-Hydroperoxy-2-nonenal-induced formation of 1,N2-etheno-2'-deoxyguanosine adducts.Chemical research in toxicology, 18 4
-
G. Poli, R. Schaur, W. Siems, G. Leonarduzzi (2008)
4‐Hydroxynonenal: A membrane lipid oxidation product of medicinal interestMedicinal Research Reviews, 28
-
P. Kowalczyk, J. Cieśla, M. Saparbaev, J. Laval, B. Tudek (2006)
Sequence-specific p53 gene damage by chloroacetaldehyde and its repair kinetics in Escherichia coli.Acta biochimica Polonica, 53 2
-
T. Obtułowicz, Alicja Winczura, E. Speina, M. Swoboda, J. Janik, B. Janowska, J. Cieśla, P. Kowalczyk, A. Jawień, D. Gackowski, Z. Banaszkiewicz, I. Krasnodębski, A. Chaber, R. Olinski, Jagadesaan Nair, H. Bartsch, T. Douki, J. Cadet, B. Tudek (2010)
Aberrant repair of etheno-DNA adducts in leukocytes and colon tissue of colon cancer patients.Free radical biology & medicine, 49 6
-
J. Jiricny, M. Menigatti (2008)
DNA Cytosine Demethylation: Are We Getting Close?Cell, 135
-
B. Janowska, D. Kurpios-Piec, Paulina Prorok, G. Szparecki, Marek Komisarski, P. Kowalczyk, C. Janion, B. Tudek (2012)
Role of damage-specific DNA polymerases in M13 phage mutagenesis induced by a major lipid peroxidation product trans-4-hydroxy-2-nonenal.Mutation research, 729 1-2
-
M. Tini, A. Benecke, S. Um, J. Torchia, R. Evans, P. Chambon (2002)
Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription.Molecular cell, 9 2
-
G. Jia, Cai-Guang Yang, Shangdong Yang, Xing Jian, C. Yi, Zhiqiang Zhou, Chuan He (2008)
Oxidative demethylation of 3‐methylthymine and 3‐methyluracil in single‐stranded DNA and RNA by mouse and human FTOFEBS Letters, 582
-
G. Jia, Ye Fu, Xu Zhao, Qing Dai, G. Zheng, Ying Yang, C. Yi, T. Lindahl, T. Pan, Yun‐Gui Yang, Chuan He (2011)
N6-Methyladenosine in Nuclear RNA is a Major Substrate of the Obesity-Associated FTONature chemical biology, 7
-
J. Nair, P. Carmichael, R. Fernando, D. Phillips, A. Strain, H. Bartsch (1998)
Lipid peroxidation-induced etheno-DNA adducts in the liver of patients with the genetic metal storage disorders Wilson's disease and primary hemochromatosis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 7 5
-
K. Tsujikawa, K. Koike, K. Kitae, Aina Shinkawa, H. Arima, Takashi Suzuki, Mutsumi Tsuchiya, Y. Makino, T. Furukawa, N. Konishi, Hiroshi Yamamoto (2007)
Expression and sub-cellular localization of human ABH family moleculesJournal of Cellular and Molecular Medicine, 11
-
K. Uchida (2003)
4-Hydroxy-2-nonenal: a product and mediator of oxidative stress.Progress in lipid research, 42 4
-
S. Langouët, Michael Müller, F. Guengerich (1997)
Misincorporation of dNTPs opposite 1,N2-ethenoguanine and 5,6,7,9-tetrahydro-7-hydroxy-9-oxoimidazo[1,2-a]purine in oligonucleotides by Escherichia coli polymerases I exo- and II exo-, T7 polymerase exo-, human immunodeficiency virus-1 reverse transcriptase, and rat polymerase beta.Biochemistry, 36 20
-
S. Stein, Y. Lao, I. Yang, S. Hecht, M. Moriya (2006)
Genotoxicity of acetaldehyde- and crotonaldehyde-induced 1,N2-propanodeoxyguanosine DNA adducts in human cells.Mutation research, 608 1
-
H. Bartsch, J. Nair (2006)
Chronic inflammation and oxidative stress in the genesis and perpetuation of cancer: role of lipid peroxidation, DNA damage, and repairLangenbeck's Archives of Surgery, 391
-
P. Aas, M. Otterlei, P. Falnes, C. Vågbø, F. Skorpen, M. Akbari, O. Sundheim, M. Bjørås, G. Slupphaug, E. Seeberg, H. Krokan (2003)
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNANature, 421
-
P. Eckl, A. Ortner, H. Esterbauer (1993)
Genotoxic properties of 4-hydroxyalkenals and analogous aldehydes.Mutation research, 290 2
-
R. Sodum, F. Chung (1991)
Stereoselective formation of in vitro nucleic acid adducts by 2,3-epoxy-4-hydroxynonanal.Cancer research, 51 1
-
R.J Schaur (2003)
Basic aspects of the biochemical reactivity of 4-hydroxynonenal.Molecular aspects of medicine, 24 4-5
-
B. Tudek, Alicja Winczura, J. Janik, A. Siomek, M. Foksiński, R. Olinski (2010)
Involvement of oxidatively damaged DNA and repair in cancer development and aging.American journal of translational research, 2 3
-
J. Nair, U. Nair, Xin Sun, Ying Wang, K. Arab, H. Bartsch (2011)
Quantifying etheno-DNA adducts in human tissues, white blood cells, and urine by ultrasensitive (32)P-postlabeling and immunohistochemistry.Methods in molecular biology, 682
-
M. Krzystek-Korpacka, B. Salmonowicz, D. Boehm, I. Berdowska, B. Zieliński, E. Patryn, A. Noczyńska, A. Gamian (2008)
Diagnostic potential of oxidative stress markers in children and adolescents with type 1 diabetes.Clinical biochemistry, 41 1-2
-
C. Privezentzev, M. Saparbaev, J. Laval (2001)
The HAP1 protein stimulates the turnover of human mismatch-specific thymine-DNA-glycosylase to process 3,N(4)-ethenocytosine residues.Mutation research, 480-481
-
Siyi Zhang, S. Balbo, Mingyao Wang, S. Hecht (2011)
Analysis of acrolein-derived 1,N2-propanodeoxyguanosine adducts in human leukocyte DNA from smokers and nonsmokers.Chemical research in toxicology, 24 1
-
Mounir Benamira, L. Marnett (1992)
The lipid peroxidation product 4-hydroxynonenal is a potent inducer of the SOS response.Mutation research, 293 1
-
C. Schneider, D. Pratt, N. Porter, A. Brash (2007)
Control of oxygenation in lipoxygenase and cyclooxygenase catalysis.Chemistry & biology, 14 5
-
Noriko Noguchi, H. Yamashita, Jun Hamahara, A. Nakamura, Hartmut Kühn, Etsuo Niki (2002)
The Specificity of Lipoxygenase-Catalyzed Lipid Peroxidation and the Effects of Radical- Scavenging Antioxidants, 383
-
A. Barbin, H. Bartsch, P. Leconte, M. Radman (1981)
Studies on the miscoding properties of 1,N6-ethenoadenine and 3,N4-ethenocytosine, DNA reaction products of vinyl chloride metabolites, during in vitro DNA synthesis.Nucleic acids research, 9 2
-
T. Duncan, S. Trewick, P. Koivisto, P. Bates, T. Lindahl, B. Sedgwick (2002)
Reversal of DNA alkylation damage by two human dioxygenasesProceedings of the National Academy of Sciences of the United States of America, 99
-
Y. Mishina, Chih-Hui Lee, Chuan He (2004)
Interaction of human and bacterial AlkB proteins with DNA as probed through chemical cross-linking studies.Nucleic acids research, 32 4
-
J. Haleng, J. Pincemail, J. Defraigne, C. Charlier, J. Chapelle (2007)
[Oxidative stress].Revue medicale de Liege, 62 10
-
(2009)
DNA repair in mammalian cells: DNA double-strand break repair: how to fix a broken relationship, 66
-
B. Janowska, Marek Komisarski, Paulina Prorok, B. Sokołowska, J. Kuśmierek, C. Janion, B. Tudek (2009)
Nucleotide excision repair and recombination are engaged in repair of trans-4-hydroxy-2-nonenal adducts to DNA bases in Escherichia coliInternational Journal of Biological Sciences, 5
-
Yusong Yang, Rajendra Sharma, Abha Sharma, S. Awasthi, Y. Awasthi (2003)
Lipid peroxidation and cell cycle signaling: 4-hydroxynonenal, a key molecule in stress mediated signaling.Acta biochimica Polonica, 50 2
-
J. Delaney, L. Smeester, Cintyu Wong, Lauren Frick, K. Taghizadeh, J. Wishnok, C. Drennan, L. Samson, J. Essigmann (2005)
AlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivoNature Structural &Molecular Biology, 12
-
G. Karlhuber, H. Bauer, P. Eckl (1997)
Cytotoxic and genotoxic effects of 4-hydroxynonenal in cerebral endothelial cells.Mutation research, 381 2
-
M. Saparbaev, S. Langouët, C. Privezentzev, F. Guengerich, H. Cai, R. Elder, J. Laval (2002)
1,N 2-Ethenoguanine, a Mutagenic DNA Adduct, Is a Primary Substrate of Escherichia coliMismatch-specific Uracil-DNA Glycosylase and Human Alkylpurine-DNA-N-Glycosylase*The Journal of Biological Chemistry, 277
-
Sushil Kumar, R. Kokate, M. Sahu, P. Chaudhary, Rajendra Sharma, S. Awasthi, Y. Awasthi (2011)
Inhibition of mercapturic acid pathway-mediated disposal of 4-hydroxynonenal causes complete and sustained remission of human cancer xenografts in nude mice.Indian journal of experimental biology, 49 11
-
A. Basu, M. Wood, L. Niedernhofer, L. Ramos, J. Essigmann (1993)
Mutagenic and genotoxic effects of three vinyl chloride-induced DNA lesions: 1,N6-ethenoadenine, 3,N4-ethenocytosine, and 4-amino-5-(imidazol-2-yl)imidazole.Biochemistry, 32 47
-
N4-ethenocytosine, a highly muta -
Zhaohui Feng, Wenwei Hu, M. Tang (2004)
Trans-4-hydroxy-2-nonenal inhibits nucleotide excision repair in human cells: a possible mechanism for lipid peroxidation-induced carcinogenesis.Proceedings of the National Academy of Sciences of the United States of America, 101 23
-
I. Suc, O. Meilhac, I. Lajoie-Mazenc, J. Vandaele, G. Jurgens, R. Salvayre, A. Nègre-Salvayre (1998)
Activation of EGF receptor by oxidized LDLThe FASEB Journal, 12
-
F. Chung, Jishen Pan, S. Choudhury, R. Roy, Wenwei Hu, M. Tang (2003)
Formation of trans-4-hydroxy-2-nonenal- and other enal-derived cyclic DNA adducts from omega-3 and omega-6 polyunsaturated fatty acids and their roles in DNA repair and human p53 gene mutation.Mutation research, 531 1-2
-
Soo-Hyoun Um, M. Harbers, A. Benecke, B. Pierrat, R. Losson, P. Chambon (1998)
Retinoic Acid Receptors Interact Physically and Functionally with the T:G Mismatch-specific Thymine-DNA Glycosylase*The Journal of Biological Chemistry, 273
-
B. Hang, A. Chenna, A. Guliaev, B. Singer (2004)
Erratum to “Miscoding properties of 1,N6-ethanoadenine, a DNA adduct derived from reaction with the antitumor agent 1,3-bis(2-chloroethyl)-1-nitrosourea”: [Mut. Res. 531 (2003) 191–203]Mutation Research, 546
-
Thomas Begley, L. Samson (2003)
AlkB mystery solved: oxidative demethylation of N1-methyladenine and N3-methylcytosine adducts by a direct reversal mechanism.Trends in biochemical sciences, 28 1
-
Karin Gilljam, Emadoldin Feyzi, P. Aas, M. Sousa, Rebekka Müller, C. Vågbø, Tara Catterall, N. Liabakk, G. Slupphaug, F. Drabløs, H. Krokan, M. Otterlei (2009)
Identification of a novel, widespread, and functionally important PCNA-binding motifThe Journal of Cell Biology, 186
-
H. Chen, F. Chung (1994)
Formation of etheno adducts in reactions of enals via autoxidation.Chemical research in toxicology, 7 6
-
M. Hegde, T. Hazra, S. Mitra (2008)
Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cellsCell Research, 18
-
D. Gackowski, E. Speina, M. Zielińska, J. Kowalewski, R. Rozalski, A. Siomek, Tomasz Paciorek, B. Tudek, R. Olinski (2003)
Products of oxidative DNA damage and repair as possible biomarkers of susceptibility to lung cancer.Cancer research, 63 16
-
R. Brigelius-Flohé (2006)
Glutathione peroxidases and redox-regulated transcription factors, 387
-
C. Schneider, K. Tallman, N. Porter, A. Brash (2001)
Two Distinct Pathways of Formation of 4-HydroxynonenalThe Journal of Biological Chemistry, 276
-
Maurizio Parola, G. Robino, Fabio Marra, M. Pinzani, Giorgio Bellomo, G. Leonarduzzi, Paola Chiarugi, S. Camandola, Giuseppe Poli, G. Waeg, Paolo Gentilini, M. Dianzani (1998)
HNE interacts directly with JNK isoforms in human hepatic stellate cells.The Journal of clinical investigation, 102 11
-
J. Nair, F. Gansauge, H. Beger, P. Dolara, G. Winde, H. Bartsch (2006)
Increased etheno-DNA adducts in affected tissues of patients suffering from Crohn's disease, ulcerative colitis, and chronic pancreatitis.Antioxidants & redox signaling, 8 5-6
-
Mutational spectrum and [132] genotoxicity of the major lipid peroxidation product -
Ulrike Begley, Madhu Dyavaiah, Ashish Patil, J. Rooney, D. Direnzo, Christine Young, D. Conklin, R. Zitomer, Thomas Begley (2007)
Trm9-catalyzed tRNA modifications link translation to the DNA damage response.Molecular cell, 28 5
-
C. Missero, M. Pirro, Silvana Simeone, M. Pischetola, R. Lauro (2001)
The DNA Glycosylase T:G Mismatch-specific Thymine DNA Glycosylase Represses Thyroid Transcription Factor-1-activated Transcription*The Journal of Biological Chemistry, 276
-
M. Saparbaev, K. Kleibl, J. Laval (1995)
Escherichia coli, Saccharomyces cerevisiae, rat and human 3-methyladenine DNA glycosylases repair 1,N6-ethenoadenine when present in DNA.Nucleic acids research, 23 18
-
Karen Almeida, R. Sobol (2007)
A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification.DNA repair, 6 6
-
T. Gerken, C. Girard, Y. Tung, Celia Webby, V. Saudek, K. Hewitson, G. Yeo, M. McDonough, Sharon Cunliffe, L. McNeill, J. Galvanovskis, P. Rorsman, P. Robins, X. Prieur, A. Coll, Marcella Ma, Z. Jovanović, I. Farooqi, B. Sedgwick, I. Barroso, T. Lindahl, C. Ponting, F. Ashcroft, S. O’Rahilly, C. Schofield (2007)
The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid DemethylaseScience, 318
-
Lene Songe-Møller, E. Born, Vibeke Leihne, C. Vågbø, Terese Kristoffersen, H. Krokan, F. Kirpekar, P. Falnes, A. Klungland (2010)
Mammalian ALKBH8 Possesses tRNA Methyltransferase Activity Required for the Biogenesis of Multiple Wobble Uridine Modifications Implicated in Translational DecodingMolecular and Cellular Biology, 30
-
B. Demple, J. Sung (2005)
Molecular and biological roles of Ape1 protein in mammalian base excision repair.DNA repair, 4 12
-
T. Müller, K. Meek, R. Hausinger (2010)
Human AlkB homologue 1 (ABH1) exhibits DNA lyase activity at abasic sites.DNA repair, 9 1
-
Zhaohui Feng, Wenwei Hu, S. Amin, M. Tang (2003)
Mutational spectrum and genotoxicity of the major lipid peroxidation product, trans-4-hydroxy-2-nonenal, induced DNA adducts in nucleotide excision repair-proficient and -deficient human cells.Biochemistry, 42 25
-
K. Žarković (2003)
4-hydroxynonenal and neurodegenerative diseases.Molecular aspects of medicine, 24 4-5
-
H. Esterbauer, R. Schaur, H. Zollner (1991)
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes.Free radical biology & medicine, 11 1
-
F. Chung, Jishen Pan, S. Choudhury, R. Roy, Wenwei Hu, M. Tang (2003)
Formation of trans-4-hydroxy-2-nonenal- and other enal-derived cyclic DNA adducts from ω-3 and ω-6 polyunsaturated fatty acids and their roles in DNA repair and human p53 gene mutationMutation Research, 531
-
M. Saparbaev, J. Laval (1998)
3,N4-ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase.Proceedings of the National Academy of Sciences of the United States of America, 95 15
-
M. Sabourin, N. Osheroff (2000)
Sensitivity of human type II topoisomerases to DNA damage: stimulation of enzyme-mediated DNA cleavage by abasic, oxidized and alkylated lesions.Nucleic acids research, 28 9
-
(2009)
DNA repair in mammalian cells: Base excision repair: the long and short of it, 66
-
P. Falnes, M. Bjørås, P. Aas, O. Sundheim, E. Seeberg (2004)
Substrate specificities of bacterial and human AlkB proteins.Nucleic acids research, 32 11
-
B. Tudek, P. Kowalczyk, J. Cieśla (1999)
Localization of chloroacetaldehyde-induced DNA damage in human p53 gene by DNA polymerase fingerprint analysis.IARC scientific publications, 150
-
Michal Kurowski, A. Bhagwat, Grzegorz Papaj, J. Bujnicki (2003)
Phylogenomic identification of five new human homologs of the DNA repair enzyme AlkBBMC Genomics, 4
-
Z. Pan, Shaheen Sikandar, Mavee Witherspoon, Diana Dizon, T. Nguyen, K. Benirschke, Christopher Wiley, P. Vrana, S. Lipkin (2008)
Impaired placental trophoblast lineage differentiation in Alkbh1−/− miceDevelopmental Dynamics, 237
-
A. Chenna, R. Rieger, C. Iden (1992)
Characterization of thymidine adducts formed by acrolein and 2-bromoacrolein.Carcinogenesis, 13 12
-
C. Yi, Cai-Guang Yang, Chuan He (2009)
A Non-Heme Iron-Mediated Chemical Demethylation in DNA and RNAChemInform, 40
-
P. Kowalczyk, J. Cieśla, Marek Komisarski, J. Kuśmierek, B. Tudek (2004)
Long-chain adducts of trans-4-hydroxy-2-nonenal to DNA bases cause recombination, base substitutions and frameshift mutations in M13 phage.Mutation research, 550 1-2
-
Regulation of rat hepatocyte protein References Lindahl T. Instability and decay of the primary structure of -
P. Burcham (1998)
Genotoxic lipid peroxidation products: their DNA damaging properties and role in formation of endogenous DNA adducts.Mutagenesis, 13 3
-
Benjamin Pardo, Belén Gómez-González, A. Aguilera (2009)
DNA Repair in Mammalian CellsCellular and Molecular Life Sciences, 66
-
M. Goodman (2002)
Error-prone repair DNA polymerases in prokaryotes and eukaryotes.Annual review of biochemistry, 71
-
DNA repair in [78] mammalian cells: DNA double-strand break repair: how to Falnes PO -
J. Nair, H. Sone, M. Nagao, A. Barbin, H. Bartsch (1996)
Copper-dependent formation of miscoding etheno-DNA adducts in the liver of Long Evans cinnamon (LEC) rats developing hereditary hepatitis and hepatocellular carcinoma.Cancer research, 56 6
-
H. Bartsch, A. Barbin, M. Marion, J. Nair, Y. Guichard (1994)
Formation, detection, and role in carcinogenesis of ethenobases in DNA.Drug metabolism reviews, 26 1-2
-
S. Choudhury, Jishen Pan, S. Amin, F. Chung, R. Roy (2004)
Repair kinetics of trans-4-hydroxynonenal-induced cyclic 1,N2-propanodeoxyguanine DNA adducts by human cell nuclear extracts.Biochemistry, 43 23
-
L. Aravind, E. Koonin (2001)
The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenasesGenome Biology, 2
-
K. Okada, Chantima Wangpoengtrakul, T. Osawa, S. Toyokuni, Keiji Tanaka, K. Uchida (1999)
4-Hydroxy-2-nonenal-mediated Impairment of Intracellular Proteolysis during Oxidative StressThe Journal of Biological Chemistry, 274
-
L. Gros, A. Maksimenko, C. Privezentzev, J. Laval, M. Saparbaev (2004)
Hijacking of the Human Alkyl-N-purine-DNA Glycosylase by 3,N4-Ethenocytosine, a Lipid Peroxidation-induced DNA Adduct*[boxs]Journal of Biological Chemistry, 279
-
William Wolfle, Robert Johnson, I. Minko, R. Lloyd, S. Prakash, L. Prakash (2006)
Replication past a trans-4-hydroxynonenal minor-groove adduct by the sequential action of human DNA polymerases iota and kappa.Molecular and cellular biology, 26 1
-
Leena Maddukuri, E. Speina, M. Christiansen, D. Dudzinska, J. Zaim, T. Obtułowicz, Sylwia Kabaczyk, Marek Komisarski, Zuzanna Bukowy, J. Szczegielniak, A. Wójcik, J. Kuśmierek, T. Stevnsner, V. Bohr, B. Tudek (2009)
Cockayne syndrome group B protein is engaged in processing of DNA adducts of lipid peroxidation product trans-4-hydroxy-2-nonenal.Mutation research, 666 1-2
-
J. Nair, A. Barbin, Ivana Velic, H. Bartsch (1999)
Etheno DNA-base adducts from endogenous reactive species.Mutation research, 424 1-2
-
Sarah Shuck, Emily Short, J. Turchi (2008)
Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biologyCell Research, 18
-
N. Gautam, Subhasis Das, S. Mahapatra, S. Chakraborty, P. Kundu, Somenath Roy (2010)
Age associated oxidative damage in lymphocytesOxidative Medicine and Cellular Longevity, 3
-
U. Nair, H. Bartsch, J. Nair (2007)
Lipid peroxidation-induced DNA damage in cancer-prone inflammatory diseases: a review of published adduct types and levels in humans.Free radical biology & medicine, 43 8
-
H. Esterbauer, P. Eckl, A. Ortner (1990)
Possible mutagens derived from lipids and lipid precursors.Mutation research, 238 3
-
B. Singer, J. Kuśmierek, W. Folkman, F. Chavez, M. Dosanjh (1991)
Evidence for the mutagenic potential of the vinyl chloride induced adduct, N2, 3-etheno-deoxyguanosine, using a site-directed kinetic assay.Carcinogenesis, 12 4
-
B. Kavli, O. Sundheim, M. Akbari, M. Otterlei, H. Nilsen, F. Skorpen, P. Aas, Lars Hagen, H. Krokan, G. Slupphaug (2002)
hUNG2 Is the Major Repair Enzyme for Removal of Uracil from U:A Matches, U:G Mismatches, and U in Single-stranded DNA, with hSMUG1 as a Broad Specificity Backup*The Journal of Biological Chemistry, 277
-
William Wolfle, Robert Johnson, I. Minko, R. Lloyd, S. Prakash, L. Prakash (2006)
Replication past a trans-4-Hydroxynonenal Minor-Groove Adduct by the Sequential Action of Human DNA Polymerases ι and κMolecular and Cellular Biology, 26
-
J. Ringvoll, M. Moen, Line Nordstrand, L. Meira, B. Pang, A. Bekkelund, P. Dedon, S. Bjelland, L. Samson, P. Falnes, A. Klungland (2008)
AlkB homologue 2-mediated repair of ethenoadenine lesions in mammalian DNA.Cancer research, 68 11
-
M. Hayashi, M. Itoh, S. Araki, S. Kumada, K. Shioda, K. Tamagawa, T. Mizutani, Y. Morimatsu, M. Oda (2001)
Oxidative Stress and Disturbed Glutamate Transport in Hereditary Nucleotide Repair DisordersJNEN: Journal of Neuropathology & Experimental Neurology, 60
-
N. Konishi, Mitsutoshi Nakamura, E. Ishida, K. Shimada, Eika Mitsui, Rintaro Yoshikawa, Hiroshi Yamamoto, K. Tsujikawa (2005)
High Expression of a New Marker PCA-1 in Human Prostate CarcinomaClinical Cancer Research, 11
-
(2001)
Two distinct pathways of formation of 4-hydroxynonenal. Mechanisms of nonenzymatic transformation of the 9-and 13-hydroperoxides of linoleic acid to 4-hydroxyalkenals, 276
-
A. Chenna, C. Iden (1993)
Characterization of 2'-deoxycytidine and 2'-deoxyuridine adducts formed in reactions with acrolein and 2-bromoacrolein.Chemical research in toxicology, 6 3
-
Kyoichiro Kanamitsu, S. Ikeda (2010)
Early Steps in the DNA Base Excision Repair Pathway of a Fission Yeast Schizosaccharomyces pombeJournal of Nucleic Acids, 2010
-
Bing-qian Liu, Yu-dong Wu, Pei-Huan Li, Jin-xing Wei, Tong Zhang, Ranlu Liu (2007)
Prostate cancer antigen-1 as a potential novel marker for prostate cancer.Asian journal of andrology, 9 6
-
Wenwei Hu, Zhaohui Feng, Jamie Eveleigh, G. Iyer, Jishen Pan, S. Amin, F. Chung, M. Tang (2002)
The major lipid peroxidation product, trans-4-hydroxy-2-nonenal, preferentially forms DNA adducts at codon 249 of human p53 gene, a unique mutational hotspot in hepatocellular carcinoma.Carcinogenesis, 23 11
-
Y. Awasthi, Rajendra Sharma, Abha Sharma, Sushma Yadav, S. Singhal, P. Chaudhary, S. Awasthi (2008)
Self-regulatory role of 4-hydroxynonenal in signaling for stress-induced programmed cell death.Free radical biology & medicine, 45 2
-
G. Pandya, M. Moriya (1996)
1,N6-ethenodeoxyadenosine, a DNA adduct highly mutagenic in mammalian cells.Biochemistry, 35 35
-
S. Tornaletti (2005)
Transcription arrest at DNA damage sites.Mutation research, 577 1-2
-
C. Licht, T. Stevnsner, V. Bohr (2003)
Cockayne syndrome group B cellular and biochemical functions.American journal of human genetics, 73 6
-
Robert Levine, I. Yang, Munfarah Hossain, G. Pandya, A. Grollman, Masaaki Moriya (2000)
Mutagenesis induced by a single 1,N6-ethenodeoxyadenosine adduct in human cells.Cancer research, 60 15
-
Werner Siems, H. Zollner, Tilman Grune, H. Esterbauer (1997)
Metabolic fate of 4-hydroxynonenal in hepatocytes: 1,4-dihydroxynonene is not the main product.Journal of lipid research, 38 3
-
T. Lindahl (1993)
Instability and decay of the primary structure of DNANature, 362
-
H. Bartsch, J. Nair (2004)
Oxidative stress and lipid peroxidation-derived DNA-lesions in inflammation driven carcinogenesis.Cancer detection and prevention, 28 6
-
B Mahy, J. Pattison, D. Kelly, N. Carr (1984)
Prokaryotes and eukaryotes -
J. Nair, O. Sinitsina, E. Vasunina, G. Nevinsky, J. Laval, H. Bartsch (2005)
Age-dependent increase of etheno-DNA-adducts in liver and brain of ROS overproducing OXYS rats.Biochemical and biophysical research communications, 336 2
-
E. Chiarpotto, C. Domenicotti, D. Paola, A. Vitali, M. Nitti, M. Pronzato, F. Biasi, D. Cottalasso, U. Marinari, A. Dragonetti, P. Cesaro, C. Isidoro, G. Poli (1999)
Regulation of rat hepatocyte protein kinase C β isoenzymes by the lipid peroxidation product 4‐hydroxy‐2,3‐nonenal: A signaling pathway to modulate vesicular transport of glycoproteinsHepatology, 29
-
(1999)
4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules, 274
-
B. Hang, A. Chenna, A. Guliaev, B. Singer (2003)
Miscoding properties of 1,N6-ethanoadenine, a DNA adduct derived from reaction with the antitumor agent 1,3-bis(2-chloroethyl)-1-nitrosourea.Mutation research, 531 1-2
-
P. Falnes (2004)
Repair of 3-methylthymine and 1-methylguanine lesions by bacterial and human AlkB proteins.Nucleic acids research, 32 21
-
(2004)
DNA-lesions in infl ammation driven carcinogenesis -
M. Valko, Mário Izakovič, M. Mazúr, C. Rhodes, J. Telser (2004)
Role of oxygen radicals in DNA damage and cancer incidenceMolecular and Cellular Biochemistry, 266
-
(1999)
Activation of stress signaling pathways by the end product of lipid peroxidation. 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production, 274
- Publisher
- Taylor & Francis
- Copyright
- © 2012 Informa UK, Ltd.
- ISSN
- 1029-2470
- eISSN
- 1071-5762
- DOI
- 10.3109/10715762.2012.658516
- pmid
- 22257221
- Publisher site
- See Article on Publisher Site
Abstract
AbstractOxidative stress and lipid peroxidation (LPO) accompanying infections and chronic inflammation may induce several human cancers. LPO products are characterized by carbohydrate chains of different length, reactive aldehyde groups and double bonds, which make these molecules reactive to nucleic acids, proteins and cellular thiols. LPO-derived adducts to DNA bases form etheno-type and propano-type exocyclic rings, which have profound mutagenic potential, and are elevated in several cancer-prone diseases. Adducts of long chain LPO products to DNA bases inhibit transcription. Elimination from DNA of LPO-induced lesions is executed by several repair systems: base excision repair (BER), direct reversal by AlkB family proteins, nucleotide excision repair (NER) and recombination. Modifications of proteins with LPO products may regulate cellular processes like apoptosis, cell signalling and senescence. This review summarizes consequences of LPO products’ presence in cell, particularly 4-hydroxy-2-nonenal, in terms of genomic stability.
Journal
Free Radical Research – Taylor & Francis
Published: Apr 1, 2012
Keywords: HNE; DNA repair; lipid peroxidation; DNA-adducts