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Cytokines and depression: fortuitous or causative association?

Cytokines and depression: fortuitous or causative association? There is an increasingly impressive database concerning the possible involvement of cytokines in depression and their role in the therapeutic effects of antidepressants. Based on the discussions which took place on these issues at a recent meeting held in Roscoff, France, this perspective summarizes in a critical way the evidence in favor of such a possibility, and points out the needs for further research to clarify both the nature of the subtle dysregulations that affect neuroendocrine-immune interactions in depressive disorders and their contribution to psychopathology. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Molecular Psychiatry Springer Journals

Cytokines and depression: fortuitous or causative association?

Dantzer, R; Wollman, E; Vitkovic, L; Yirmiya, R
Molecular Psychiatry , Volume 4 (4) – Sep 10, 1999
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References (41)

Publisher
Springer Journals
Copyright
Copyright © 1999 by Macmillan Publishers Limited
Subject
Medicine & Public Health; Medicine/Public Health, general; Psychiatry; Neurosciences; Behavioral Sciences; Pharmacotherapy; Biological Psychology
ISSN
1359-4184
eISSN
1476-5578
DOI
10.1038/sj.mp.4000572
Publisher site
See Article on Publisher Site

Abstract

There is an increasingly impressive database concerning the possible involvement of cytokines in depression and their role in the therapeutic effects of antidepressants. Based on the discussions which took place on these issues at a recent meeting held in Roscoff, France, this perspective summarizes in a critical way the evidence in favor of such a possibility, and points out the needs for further research to clarify both the nature of the subtle dysregulations that affect neuroendocrine-immune interactions in depressive disorders and their contribution to psychopathology.

Journal

Molecular Psychiatry – Springer Journals

Published: Sep 10, 1999

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