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Uterine Papillary Serous Carcinoma

Uterine Papillary Serous Carcinoma Downloaded from http://journals.lww.com/clinicalobgyn by BhDMf5ePHKbH4TTImqenVA5KvPVPZ0P5BEgU+IUTEfzO/GUWifn2IfwcEVVH9SSn on 06/09/2020 CLINICAL OBSTETRICS AND GYNECOLOGY Volume 54, Number 2, 278–291 r 2011, Lippincott Williams & Wilkins Uterine Papillary Serous Carcinoma KATHLEEN N. MOORE, MD* and AMANDA NICKLES FADER, MDw *Department of Gynecologic Oncology, University of Oklahoma, Oklahoma City, Oklahoma; and w Greater Baltimore Medical Center, Baltimore, Maryland Abstract: Uterine papillary serous carcinoma (UPSC) with uterine papillary serous carcinoma is a histologic variant of endometrial cancer that (UPSC). This uncommon histologic sub- accounts for only 10% of new cases of uterine cancer type represents only 10% of endometrial but is responsible for 40% of deaths from the disease. cancer cases but is responsible for a dis- UPSC is an aggressive tumor with a predilection for early spread beyond the uterus. Treatment for UPSC proportionate 40% of deaths due to en- typically entails surgery and in most women is fol- dometrial cancer. This higher rate of lowed by multimodality adjuvant therapy. In this cancer-related mortality is attributed to review, we describe the epidemiology, natural history, the inherent biological aggression of treatment, and outcome of UPSC. USPC compared with the more common Key words: uterine papillary serous carcinoma, serous carcinoma, endometrial cancer endometrioid subtype. In clinically http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Obstetrics & Gynecology Wolters Kluwer Health

Uterine Papillary Serous Carcinoma

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Publisher
Wolters Kluwer Health
ISSN
0009-9201
eISSN
1532-5520
DOI
10.1097/GRF.0b013e318218c755
Publisher site
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Abstract

Downloaded from http://journals.lww.com/clinicalobgyn by BhDMf5ePHKbH4TTImqenVA5KvPVPZ0P5BEgU+IUTEfzO/GUWifn2IfwcEVVH9SSn on 06/09/2020 CLINICAL OBSTETRICS AND GYNECOLOGY Volume 54, Number 2, 278–291 r 2011, Lippincott Williams & Wilkins Uterine Papillary Serous Carcinoma KATHLEEN N. MOORE, MD* and AMANDA NICKLES FADER, MDw *Department of Gynecologic Oncology, University of Oklahoma, Oklahoma City, Oklahoma; and w Greater Baltimore Medical Center, Baltimore, Maryland Abstract: Uterine papillary serous carcinoma (UPSC) with uterine papillary serous carcinoma is a histologic variant of endometrial cancer that (UPSC). This uncommon histologic sub- accounts for only 10% of new cases of uterine cancer type represents only 10% of endometrial but is responsible for 40% of deaths from the disease. cancer cases but is responsible for a dis- UPSC is an aggressive tumor with a predilection for early spread beyond the uterus. Treatment for UPSC proportionate 40% of deaths due to en- typically entails surgery and in most women is fol- dometrial cancer. This higher rate of lowed by multimodality adjuvant therapy. In this cancer-related mortality is attributed to review, we describe the epidemiology, natural history, the inherent biological aggression of treatment, and outcome of UPSC. USPC compared with the more common Key words: uterine papillary serous carcinoma, serous carcinoma, endometrial cancer endometrioid subtype. In clinically

Journal

Clinical Obstetrics & Gynecology – Wolters Kluwer Health

Published: Jun 1, 2011

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