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Neuropsychopharmacology (2003) 28, 397–401 & 2003 Nature Publishing Group All rights reserved 0893-133X/03 $25.00 www.neuropsychopharmacology.org A BDNF Coding Variant is Associated with the NEO Personality Inventory Domain Neuroticism, a Risk Factor for Depression 1 2,3 2,4 5 6 Srijan Sen , Randolph M. Nesse , Scott F. Stoltenberg , Sheng Li , Lillian Gleiberman , Aravinda 8 6 ,1,2,5,7 Chakravarti , Alan B. Weder and Margit Burmeister* 1 2 Neuroscience Program, University of Michigan, Ann Arbor, MI, USA; Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA; 3 4 Department of Psychology, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA; Addiction Research Center, University of 5 6 Michigan, Ann Arbor, MI, USA; Mental Health Research Institute, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine, 7 8 University of Michigan, Ann Arbor, MI 48105, USA; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA; McKusick- Nathans Institute of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, USA Neuropsychopharmacology (2003) 28, 397–401. doi:10.1038/sj.npp.1300053 Keywords: neurotrophin; NEO-PI; personality; polymorphism; anxiety; neurogenesis INTRODUCTION allele was associated with significantly lower mean Neuroti- cism scores (p¼ 0.0057). Our study provides further Genetic factors influence
Neuropsychopharmacology – Springer Journals
Published: Aug 29, 2002
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