R. Doms, D. Trono (2000)
The plasma membrane as a combat zone in the HIV battlefield.Genes & development, 14 21
Benhur Lee, M. Sharron, L. Montaner, D. Weissman, R. Doms (1999)
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages.Proceedings of the National Academy of Sciences of the United States of America, 96 9
C. Lapham, J. Ouyang, B. Chandrasekhar, N. Nguyen, D. Dimitrov, H. Golding (1996)
Evidence for Cell-Surface Association Between Fusin and the CD4-gp120 Complex in Human Cell LinesScience, 274
P. Kwong, R. Wyatt, James Robinson, R. Sweet, J. Sodroski, W. Hendrickson (1998)
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibodyNature, 393
T. Dragic, A. Trkola, Daniah Thompson, E. Cormier, F. Kajumo, Elizabeth Maxwell, Steven Lin, W. Ying, Steven Smith, T. Sakmar, John Moore (2000)
A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5.Proceedings of the National Academy of Sciences of the United States of America, 97 10
Benhur Lee, M. Sharron, C. Blanpain, B. Doranz, J. Vakili, Pui Setoh, E. Berg, Gao-Qi Liu, H. Guy, S. Durell, M. Parmentier, Chung Chang, K. Price, M. Tsang, R. Doms (1999)
Epitope Mapping of CCR5 Reveals Multiple Conformational States and Distinct but Overlapping Structures Involved in Chemokine and Coreceptor Function*The Journal of Biological Chemistry, 274
M. Tersmette, Y. RUUDE., De, Goede, AL BERTJ.M., I. Winkel, R. Gruters, H. Cuypers, G. Han, Huisman, F. Miedema (1988)
Differential syncytium-inducing capacity of human immunodeficiency virus isolates: frequent detection of syncytium-inducing isolates in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complexJournal of Virology, 62
T. Hoffman, R. Doms (1999)
HIV-1 envelope determinants for cell tropism and chemokine receptor use.Molecular membrane biology, 16 1
M. Samson, F. Libert, B. Doranz, J. Rucker, C. Liesnard, C. Farber, S. Saragosti, C. Lapouméroulie, Jacqueline Cognaux, C. Forceille, G. Muyldermans, C. Verhofstede, G. Burtonboy, M. Georges, T. Imai, Shalini Rana, Y. Yi, R. Smyth, R. Collman, R. Doms, G. Vassart, M. Parmentier (1996)
Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor geneNature, 382
B. Doranz, M. Orsini, J. Turner, T. Hoffman, J. Berson, J. Hoxie, S. Peiper, L. Brass, R. Doms (1999)
Identification of CXCR4 Domains That Support Coreceptor and Chemokine Receptor FunctionsJournal of Virology, 73
B. Doranz, L. Filion, F. Diaz-Mitoma, D. Sitar, J. Sahai, F. Baribaud, M. Orsini, J. Benovic, W. Cameron, R. Doms (2001)
Safe use of the CXCR4 inhibitor ALX40-4C in humans.AIDS research and human retroviruses, 17 6
Carlo Rizzuto, R. Wyatt, Nivia Hernández-Ramos, Ying Sun, P. Kwong, W. Hendrickson, J. Sodroski (1998)
A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding.Science, 280 5371
S. Pöhlmann, F. Baribaud, Benhur Lee, G. Leslie, Melissa Sanchez, Kirsten Hiebenthal-Millow, J. Münch, F. Kirchhoff, R. Doms (2001)
DC-SIGN Interactions with Human Immunodeficiency Virus Type 1 and 2 and Simian Immunodeficiency VirusJournal of Virology, 75
Rong Liu, W. Paxton, Sunny Choe, Daniel Ceradini, S. Martin, R. Horuk, M. MacDonald, H. Stuhlmann, R. Koup, N. Landau (1996)
Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 InfectionCell, 86
M. Baba, Osamu Nishimura, N. Kanzaki, M. Okamoto, H. Sawada, Y. Iizawa, M. Shiraishi, Y. Aramaki, K. Okonogi, Y. Ogawa, Kanji Meguro, M. Fujino (1999)
A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity.Proceedings of the National Academy of Sciences of the United States of America, 96 10
E. Platt, K. Wehrly, S. Kuhmann, B. Chesebro, D. Kabat (1998)
Effects of CCR5 and CD4 Cell Surface Concentrations on Infections by Macrophagetropic Isolates of Human Immunodeficiency Virus Type 1Journal of Virology, 72
Lijun Wu, N. Gerard, R. Wyatt, H. Choe, C. Parolin, N. Ruffing, A. Borsetti, A. Cardoso, Elizabeth Desjardin, W. Newman, C. Gerard, J. Sodroski (1996)
CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5Nature, 384
H. Nakashima, M. Masuda, T. Murakami, '. Koyanagi, A. Matsumoto, N. Fujii, '. Naokiyamamoto (1992)
Anti-human immunodeficiency virus activity of a novel synthetic peptide, T22 ([Tyr-5,12, Lys-7]polyphemusin II): a possible inhibitor of virus-cell fusionAntimicrobial Agents and Chemotherapy, 36
M. Endres, P. Clapham, M. Marsh, M. Ahuja, J. Turner, Á. McKnight, Jill Thomas, Beth Stoebenau-Haggarty, Sunny Choe, P. Vance, T. Wells, C. Power, S. Sutterwala, R. Doms, N. Landau, J. Hoxie (1996)
CD4-Independent Infection by HIV-2 Is Mediated by Fusin/CXCR4Cell, 87
E. Berger, P. Murphy, J. Farber (1999)
Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease.Annual review of immunology, 17
B. Doranz, K. Grovit-Ferbas, M. Sharron, S. Mao, M. Goetz, E. Daar, R. Doms, W. O'brien (1997)
A Small-molecule Inhibitor Directed against the Chemokine Receptor CXCR4 Prevents its Use as an HIV-1 CoreceptorThe Journal of Experimental Medicine, 186
N. Signoret, J. Oldridge, A. Pelchen-Matthews, P. Klasse, T. Tran, L. Brass, M. Rosenkilde, T. Schwartz, W. Holmes, W. Dallas, M. Luther, T. Wells, J. Hoxie, M. Marsh (1997)
Phorbol Esters and SDF-1 Induce Rapid Endocytosis and Down Modulation of the Chemokine Receptor CXCR4The Journal of Cell Biology, 139
R. Doms, John Moore (2000)
HIV-1 Membrane Fusion: Targets of Opportunity
A. Brelot, N. Heveker, M. Montes, M. Alizon (2000)
Identification of Residues of CXCR4 Critical for Human Immunodeficiency Virus Coreceptor and Chemokine Receptor Activities*The Journal of Biological Chemistry, 275
M. Tersmette, R. Gruters, '. Wolf, R. Goede, A. 'JOEPM., Lange, P. Schellekens, J. Goudsmit, H. Huisman (1989)
Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome: studies on sequential HIV isolatesJournal of Virology, 63
R. Connor, Benjamin Chen, Sunny Choe, N. Landau (1995)
Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes.Virology, 206 2
A. Brelot, N. Heveker, O. Pleskoff, Nathalie Sol, M. Alizon (1997)
Role of the first and third extracellular domains of CXCR-4 in human immunodeficiency virus coreceptor activityJournal of Virology, 71
M. Dean, M. Carrington, Christoph Winkler, G. Huttley, M. Smith, R. Allikmets, J. Goedert, S. Buchbinder, E. Vittinghoff, E. Gomperts, S. Donfield, D. Vlahov, R. Kaslow, A. Saah, C. Rinaldo, R. Detels, S. O’Brien (1996)
Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural GeneScience, 273
Deborah Brown, J. Rose (1992)
Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surfaceCell, 68
D. Chabot, H. Chen, D. Dimitrov, C. Broder (2000)
N-Linked Glycosylation of CXCR4 Masks Coreceptor Function for CCR5-Dependent Human Immunodeficiency Virus Type 1 IsolatesJournal of Virology, 74
W. Zhang, G. Canziani, C. Plugariu, R. Wyatt, J. Sodroski, R. Sweet, P. Kwong, W. Hendrickson, I. Chaiken (1999)
Conformational changes of gp120 in epitopes near the CCR5 binding site are induced by CD4 and a CD4 miniprotein mimetic.Biochemistry, 38 29
A. Kay (1991)
LymphocytesClinical & Experimental Allergy, 21
J. Rucker, M. Samson, B. Doranz, F. Libert, J. Berson, Y. Yi, R. Smyth, R. Collman, C. Broder, G. Vassart, R. Doms, M. Parmentier (1996)
Regions in β-Chemokine Receptors CCR5 and CCR2b That Determine HIV-1 Cofactor SpecificityCell, 87
(1998)
HIV coreceptor use: a molecular window into viral tropism
Xiaodong Xiao, David Norwood, Yan‐Ru Feng, M. Moriuchi, Agnes Jones-Trower, T. Stantchev, Hiroyuki Moriuchi, Christopher Broder, Dimiter Dimitrov (2000)
Inefficient formation of a complex among CXCR4, CD4 and gp120 in U937 clones resistant to X4 gp120-gp41-mediated fusion.Experimental and molecular pathology, 68 3
A. Trkola, T. Dragic, J. Arthos, J. Binley, W. Olson, G. Allaway, C. Cheng‐Mayer, James Robinson, P. Maddon, John Moore (1996)
CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5Nature, 384
W. Paxton, Rong Liu, Stanley Kang, Lijun Wu, T. Gingeras, Nathanial Landau, C. Mackay, R. Koup (1998)
Reduced HIV-1 infectability of CD4+ lymphocytes from exposed-uninfected individuals: association with low expression of CCR5 and high production of beta-chemokines.Virology, 244 1
T. Murakami, T. Nakajima, Y. Koyanagi, Kazunobu Tachibana, N. Fujii, H. Tamamura, N. Yoshida, M. Waki, A. Matsumoto, O. Yoshie, T. Kishimoto, N. Yamamoto, T. Nagasawa (1997)
A Small Molecule CXCR4 Inhibitor that Blocks T Cell Line–tropic HIV-1 InfectionThe Journal of Experimental Medicine, 186
T. Iiri, Z. Farfel, H. Bourne (1998)
G-protein diseases furnish a model for the turn-on switchNature, 394
C. Bleul, M. Farzan, H. Choe, C. Parolin, I. Clark‐Lewis, J. Sodroski, T. Springer (1996)
The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entryNature, 382
M. Orsini, J. Parent, S. Mundell, J. Benovic (1999)
Trafficking of the HIV Coreceptor CXCR4The Journal of Biological Chemistry, 274
T. Dragic, A. Trkola, Steven Lin, K. Nagashima, F. Kajumo, Lu Zhao, W. Olson, Lijun Wu, C. Mackay, G. Allaway, T. Sakmar, John Moore, P. Maddon (1998)
Amino-Terminal Substitutions in the CCR5 Coreceptor Impair gp120 Binding and Human Immunodeficiency Virus Type 1 EntryJournal of Virology, 72
M. Honczarenko, R. Douglas, C. Mathias, Benhur Lee, M. Ratajczak, L. Silberstein (1999)
SDF-1 responsiveness does not correlate with CXCR4 expression levels of developing human bone marrow B cells.Blood, 94 9
G. Karlsson, M. Halloran, Dominik Schenten, Juliette Lee, P. Rácz, K. Tenner‐Racz, J. Manola, R. Gelman, Bijan Etemad-Moghadam, E. Desjardins, R. Wyatt, N. Gerard, L. Marcon, D. Margolin, J. Fanton, M. Axthelm, N. Letvin, J. Sodroski (1998)
The Envelope Glycoprotein Ectodomains Determine the Efficiency of CD4+ T Lymphocyte Depletion in Simian– Human Immunodeficiency Virus–Infected MacaquesThe Journal of Experimental Medicine, 188
George Donzella, D. Schols, Steven Lin, J. Esté, K. Nagashima, P. Maddon, G. Allaway, T. Sakmar, G. Henson, E. Declercq, J. Moore (1998)
AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptorNature Medicine, 4
L. Limbird (1986)
Cell Surface Receptors: A Short Course on Theory and Methods
Bettina Tilton, Liza Ho, E. Oberlin, P. Loetscher, F. Baleux, I. Clark‐Lewis, M. Thelen (2000)
Signal transduction by CXC chemokine receptor 4. Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes.Journal of Experimental Medicine, 192
Qing Liu, Darlisha Williams, C. Mcmanus, F. Baribaud, R. Doms, D. Schols, E. Clercq, M. Kotlikoff, R. Collman, B. Freedman (2000)
HIV-1 gp120 and chemokines activate ion channels in primary macrophages through CCR5 and CXCR4 stimulation.Proceedings of the National Academy of Sciences of the United States of America, 97 9
(1959)
O'Brien's
M. Farzan, T. Mirzabekov, P. Kolchinsky, R. Wyatt, M. Cayabyab, N. Gerard, C. Gerard, J. Sodroski, H. Choe (1999)
Tyrosine Sulfation of the Amino Terminus of CCR5 Facilitates HIV-1 EntryCell, 96
B. Willett, K. Adema, N. Heveker, A. Brelot, L. Picard, M. Alizon, J. Turner, J. Hoxie, Stephen Peiper, J. Neil, M. Hosie (1998)
The Second Extracellular Loop of CXCR4 Determines Its Function as a Receptor for Feline Immunodeficiency VirusJournal of Virology, 72
S. Kuhmann, E. Platt, S. Kozak, D. Kabat (2000)
Cooperation of Multiple CCR5 Coreceptors Is Required for Infections by Human Immunodeficiency Virus Type 1Journal of Virology, 74
J. Strizki, J. Turner, R. Collman, J. Hoxie, F. González-Scarano (1997)
A monoclonal antibody (12G5) directed against CXCR-4 inhibits infection with the dual-tropic human immunodeficiency virus type 1 isolate HIV-1(89.6) but not the T-tropic isolate HIV-1(HxB)Journal of Virology, 71
A. Edinger, T. Hoffman, M. Sharron, Benhur Lee, B. O'dowd, R. Doms (1998)
Use of GPR1, GPR15, and STRL33 as coreceptors by diverse human immunodeficiency virus type 1 and simian immunodeficiency virus envelope proteins.Virology, 249 2
Stéphane Genoud, F. Kajumo, Yong Guo, Daniah Thompson, T. Dragic (1999)
CCR5-Mediated Human Immunodeficiency Virus Entry Depends on an Amino-Terminal gp120-Binding Site and on the Conformational Integrity of All Four Extracellular DomainsJournal of Virology, 73
S. Kozak, E. Platt, N Madani, F. Ferro, K. Peden, D. Kabat (1997)
CD4, CXCR-4, and CCR-5 dependencies for infections by primary patient and laboratory-adapted isolates of human immunodeficiency virus type 1Journal of Virology, 71
J. Berson, D. Long, B. Doranz, J. Rucker, F. Jirik, R. Doms (1996)
A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strainsJournal of Virology, 70
B. Doranz, Zhao-hai Lu, J. Rucker, Tian-yuan Zhang, M. Sharron, Y. Cen, Zi-Xuan Wang, H. Guo, J. Du, M. Accavitti, R. Doms, S. Peiper (1997)
Two distinct CCR5 domains can mediate coreceptor usage by human immunodeficiency virus type 1Journal of Virology, 71
M. Sharron, S. Pöhlmann, K. Price, E. Lolis, M. Tsang, F. Kirchhoff, R. Doms, Benhur Lee (2000)
Expression and coreceptor activity of STRL33/Bonzo on primary peripheral blood lymphocytes.Blood, 96 1
Á. McKnight, D. Wilkinson, G. Simmons, S. Talbot, L. Picard, M. Ahuja, M. Marsh, J. Hoxie, P. Clapham (1997)
Inhibition of human immunodeficiency virus fusion by a monoclonal antibody to a coreceptor (CXCR4) is both cell type and virus strain dependentJournal of Virology, 71
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