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A. Craig-Holmes, F. Moore, M. Shaw (1973)
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C- and Q-band polymorphisms in the chromosomes of three human populations BY K. E. BUCKTON, M. L. OâRIORDAN, P. A. JACOBS,* J. A. ROBINSON, R. HILL? AND H. J. EVANS Medical Research Council, Clinical and Population Cytogenetics Unit, Western General Hospital, Edinburgh, and * University of Hawaii, School of Medicine, Department of Anatomy, Honolulu, U.S.A., and t Castlebay, Barra, Outer Hebrides Many studies on human chromosomes stained with Giemsa or Aceto Orcein and carried out prior to 1971, had revealed that there was a great deal of polymorphism within certain chromosome pairs in the complement; in particular pairs 1, 9 and 16 and also the D and 0 group chromosomes. With the advent of the new chromosome banding techniques, and especially the &-banding (Caspersson et al. 1970, 1971) and C-banding (Arrighi & Hsu, 1971) methods, these and other polymorphisms have become much easier to visualize (Evans, Buckton & Sumner, 1971) and eventually to quantify by an automated process (Mason et al. 1975). With these techniques, polymorphisms can now be seen with ease on ten autosomes, pair numbers 1, 3, 4, 9, 13, 14, 15, 16, 21 and 22, and can be used to âmarkâ essentially normal chromosomes in
Annals of Human Genetics – Wiley
Published: Jul 1, 1976
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