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Detection of recurrent nasopharyngeal carcinoma: MR imaging versus CT.

Detection of recurrent nasopharyngeal carcinoma: MR imaging versus CT. PURPOSE: To compare the use of magnetic resonance (MR) imaging and computed tomography (CT) in detection of recurrent nasopharyngeal carcinoma. MATERIALS AND METHODS: Forty-five sets of CT and MR images were obtained in 34 patients. The images were placed in three categories: (a) clinically or radiologically abnormal findings in patients who underwent biopsy (n = 16), (b) clinically normal and radiologically borderline findings in patients who were followed up clinically and radiologically (n = 10), and (c) clinically and radiologically normal findings in patients who were monitored only clinically (n = 19). All images were read by two observers independently. RESULTS: There were nine positive and seven negative biopsy results. All patients in the latter two categories had normal findings at followup. CT had a sensitivity of 45% and 67% and a specificity of 64% and 70% for each of the two observers. MR imaging had a sensitivity of 56% (for both observers) and a specificity of 78% and 83%. The kappa test for interobserver concordance was 0.53 for CT and 0.66 for MR imaging. CONCLUSION: Both modalities have relatively low sensitivity and moderate specificity in detection of tumor recurrence and in distinguishing recurrence from post-radiation therapy changes. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Radiology Radiological Society of North America, Inc.

Detection of recurrent nasopharyngeal carcinoma: MR imaging versus CT.

Chong, V F; Fan, Y F
Radiology , Volume 202 (2): 463 – Feb 1, 1997
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Publisher
Radiological Society of North America, Inc.
Copyright
Copyright © 1997 by Radiological Society of North America
ISSN
1527-1315
eISSN
0033-8419
Publisher site
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Abstract

PURPOSE: To compare the use of magnetic resonance (MR) imaging and computed tomography (CT) in detection of recurrent nasopharyngeal carcinoma. MATERIALS AND METHODS: Forty-five sets of CT and MR images were obtained in 34 patients. The images were placed in three categories: (a) clinically or radiologically abnormal findings in patients who underwent biopsy (n = 16), (b) clinically normal and radiologically borderline findings in patients who were followed up clinically and radiologically (n = 10), and (c) clinically and radiologically normal findings in patients who were monitored only clinically (n = 19). All images were read by two observers independently. RESULTS: There were nine positive and seven negative biopsy results. All patients in the latter two categories had normal findings at followup. CT had a sensitivity of 45% and 67% and a specificity of 64% and 70% for each of the two observers. MR imaging had a sensitivity of 56% (for both observers) and a specificity of 78% and 83%. The kappa test for interobserver concordance was 0.53 for CT and 0.66 for MR imaging. CONCLUSION: Both modalities have relatively low sensitivity and moderate specificity in detection of tumor recurrence and in distinguishing recurrence from post-radiation therapy changes.

Journal

Radiology – Radiological Society of North America, Inc.

Published: Feb 1, 1997

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