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- Publisher
- Springer Journals
- Copyright
- Copyright © 2011 by Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE)
- Subject
- Medicine & Public Health; Ultrasound; Cardiology; Nuclear Medicine; Imaging / Radiology
- ISSN
- 0174-1551
- eISSN
- 1432-086X
- DOI
- 10.1007/s00270-011-0142-x
- pmid
- 21431970
- Publisher site
- See Article on Publisher Site
Abstract
Cardiovasc Intervent Radiol (2012) 35:105–116 DOI 10.1007/s00270-011-0142-x CLINICAL INVESTIGATI O N Transarterial Hepatic Yttrium-90 Radioembolization in Patients with Unresectable Intrahepatic Cholangiocarcinoma: Factors Associated with Prolonged Survival • • • • Ralf-T. Hoffmann Philipp M. Paprottka Agnes Scho ¨ n Fabian Bamberg • • • • Alexander Haug Eva-Maria Du ¨ rr Barbara Rauch Christoph T. Trumm • • • Tobias F. Jakobs Thomas K. Helmberger Maximilian F. Reiser Frank T. Kolligs Received: 19 November 2010 / Accepted: 25 February 2011 / Published online: 24 March 2011 Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2011 Abstract Methods Patients with unresectable ICC were treated with Introduction In unresectable intrahepatic cholangiocar- Y resin-microspheres and assessed at 3-monthly intervals. cinoma (ICC), systemic chemotherapy often is viewed as Radiologic response was evaluated by using Response the only option, although efficacy is limited. Radioembo- Criteria in Solid Tumors (RECIST). Baseline characteris- lization (RE) using yttrium-90 ( Y) microspheres is an tics, biochemical/clinical toxicities, and response were accepted therapy for patients with hepatocellular-carci- examined for impact on TTP and OS. noma or metastatic liver tumors. However, there are lim- Results Thirty-four treatments were administered to 33 ited data on
Journal
CardioVascular and Interventional Radiology – Springer Journals
Published: Mar 24, 2011