Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/springer-journals/inhibitory-effects-of-tanshinone-ii-a-on-invasion-and-metastasis-of-H4XXndlApg
References (51)
-
Y. Yoon, Y. Kim, W. Jeon, H. Park, H. Sung (1999)
Tanshinone IIA isolated from Salvia miltiorrhiza BUNGE induced apoptosis in HL60 human premyelocytic leukemia cell line.Journal of ethnopharmacology, 68 1-3
-
Haifeng Jin, Yanglin Pan, Lijie He, Hui-hong Zhai, Xiaohua Li, Lina Zhao, Li Sun, Jie Liu, L. Hong, Jiu-gang Song, Huahong Xie, Juan Gao, Shuang-yin Han, Y. Li, D. Fan (2007)
p 75 Neurotrophin Receptor Inhibits Invasion and Metastasis of Gastric Cancer -
B. Wolpin, J. Meyerhardt, H. Mamon, R. Mayer (2007)
Adjuvant Treatment of Colorectal CancerCA: A Cancer Journal for Clinicians, 57
-
Shunji Matsumura, N. Oue, H. Nakayama, Y. Kitadai, Kazuhiro Yoshida, Y. Yamaguchi, K. Imai, K. Nakachi, K. Matsusaki, K. Chayama, W. Yasui (2004)
A single nucleotide polymorphism in the MMP-9 promoter affects tumor progression and invasive phenotype of gastric cancerJournal of Cancer Research and Clinical Oncology, 131
-
Xinmei Kang, Qing-yuan Zhang, Dan-dan Tong, Wen-Wu Zhao (2005)
[Experimental study on anti-angiogenesis in mice with Lewis lung carcinoma by low-dose of cyclophosphamide combined with ginsenoside Rg3].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 25 8
-
P. Greenwald (1992)
Colon cancer overviewCancer, 70
-
E. Pihl, E. Hughes, F. McDermott, B. Milne, A. Price (1981)
Disease‐free survival and recurrence after resection of colorectal carcinomaJournal of Surgical Oncology, 16
-
J. Cresanta (1992)
Epidemiology of cancer in the United States.Primary care, 19 3
-
H. Sung, S. Choi, Y. Yoon, K. An (1999)
Tanshinone IIA, an ingredient of Salvia miltiorrhiza BUNGE, induces apoptosis in human leukemia cell lines through the activation of caspase-3Experimental & Molecular Medicine, 31
-
V. Bours, G. Bonizzi, M. Bentires-Alj, F. Bureau, J. Piette, P. Lekeux, M. Merville (2000)
NF-kappaB activation in response to toxical and therapeutical agents: role in inflammation and cancer treatment.Toxicology, 153 1-3
-
Claire Legrand, C. Gilles, J. Zahm, M. Polette, A. Buisson, H. Kaplan, P. Birembaut, J. Tournier (1999)
Airway Epithelial Cell Migration Dynamics: MMP-9 Role in Cell–Extracellular Matrix RemodelingJournal of Cell Biology, 146
-
N. Dubrawsky (1989)
Cancer statisticsCA: A Cancer Journal for Clinicians, 39
-
Fatima Khwaja, D. Djakiew (2003)
Inhibition of cell‐cycle effectors of proliferation in bladder tumor epithelial cells by the p75NTR tumor suppressorMolecular Carcinogenesis, 36
-
J. Cho, H. Chung, S. Noh, J. Roh, J. Min, Byung Kim (1997)
High level of urokinase‐type plasminogen activator is a new prognostic marker in patients with gastric carcinomaCancer, 79
-
Qingyuan Zhang, Xinmei Kang, W. Zhao (2006)
Antiangiogenic effect of low-dose cyclophosphamide combined with ginsenoside Rg3 on Lewis lung carcinoma.Biochemical and biophysical research communications, 342 3
-
W El-Rifai, SM Powell (2002)
Molecular biology of gastric cancerSemin Radiat Oncol, 12
-
W. Liu, S. Xu, C. Che (2000)
Anti-proliferative effect of ginseng saponins on human prostate cancer cell line.Life sciences, 67 11
-
Deqing Sun, Stefan Roth, Michael Black (2001)
반도체 공정 overview, 28
-
A. Farina, A. Coppa, A. Tiberio, A. Tacconelli, A. Turco, G. Colletta, A. Gulino, A. Mackay (1998)
Transforming growth factor-beta1 enhances the invasiveness of human MDA-MB-231 breast cancer cells by up-regulating urokinase activity.International journal of cancer, 75 5
-
Wu-Lung Wu, Wen-liang Chang, Chia-Fu Chen (1991)
Cytotoxic activities of tanshinones against human carcinoma cell lines.The American journal of Chinese medicine, 19 3-4
-
Z. Zeng, A. Cohen, J. Guillem (1999)
Loss of basement membrane type IV collagen is associated with increased expression of metalloproteinases 2 and 9 (MMP-2 and MMP-9) during human colorectal tumorigenesis.Carcinogenesis, 20 5
-
P. Guilford, J. Hopkins, J. Harraway, M. McLeod, N. McLeod, Pauline Harawira, H. Taite, Robin Scoular, A. Miller, A. Reeve (1998)
E-cadherin germline mutations in familial gastric cancerNature, 392
-
P. Luo, Zheng-huai Tan, Zhifeng Zhang, Honghao Li, Zhengji Mo (2008)
Inhibitory effects of salvianolic acid B on the high glucose-induced mesangial proliferation via NF-kappaB-dependent pathway.Biological & pharmaceutical bulletin, 31 7
-
B. Pestalozzi, D. Jäger, A. Knuth (2005)
[Systemic therapy for colorectal cancer].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 76 6
-
J. Iwamoto, Y. Mizokami, Kimiko Takahashi, K. Nakajima, T. Ohtsubo, S. Miura, T. Narasaka, H. Takeyama, T. Omata, Koichi Shimokobe, Masanori Ito, Hisashi Takehara, T. Matsuoka (2005)
Expressions of urokinase-type plasminogen activator, its receptor and plasminogen activator inhibitor-1 in gastric cancer cells and effects of Helicobacter pyloriScandinavian Journal of Gastroenterology, 40
-
JA Meyerhardt, RJ Mayer (2005)
Systemic therapy for colorectal cancerN Engl J Med, 352
-
Ph.D. M.D. (2004)
Molecular biology of gastric cancerWorld Journal of Surgery, 19
-
(2004)
Acta Pharmacologica Sinica npg carcinoma cells. World J Gastroenterol -
C. Su, Guang-wei Chen, Jung-Cheng Kang, M. Chan (2008)
Growth inhibition and apoptosis induction by tanshinone IIA in human colon adenocarcinoma cells.Planta medica, 74 11
-
Junxia Chen, Huimin Peng, Ou-Yang Xi, Xiao-yan He (2008)
Research on the antitumor effect of ginsenoside Rg3 in B16 melanoma cellsMelanoma Research, 18
-
R. Auwardt, S. Mudge, C.-G. Chen, D. Power (2000)
Inhibition with Antisense Oligonucleotide Suggests that IκB-α Does Not Form a Negative Autoregulatory Loop for NF-κB in Mesangial CellsNephron Experimental Nephrology, 8
-
H. Kuramochi, K. Hayashi, K. Uchida, S. Miyakura, D. Shimizu, D. Vallböhmer, Seongjin Park, K. Danenberg, K. Takasaki, P. Danenberg (2006)
Vascular Endothelial Growth Factor Messenger RNA Expression Level Is Preserved in Liver Metastases Compared with Corresponding Primary Colorectal CancerClinical Cancer Research, 12
-
T. Kaneko, H. Konno, Megumi Baba, Tatsuo Tanaka, Satoshi Nakamura (2003)
Urokinase‐type plasminogen activator expression correlates with tumor angiogenesis and poor outcome in gastric cancerCancer Science, 94
-
S. Yuan, Yu‐quan Wei, Xiu-jie Wang, F. Xiao, Shengguo Li, Jie Zhang (2004)
Growth inhibition and apoptosis induction of tanshinone II-A on human hepatocellular carcinoma cells.World journal of gastroenterology, 10 14
-
Hyun-sook Kim, Eun-hee Lee, S. Ko, Kang-Ju Choi, Jong-hee Park, D. Im (2004)
Effects of ginsenosides Rg3 and Rh2 on the proliferation of prostate cancer cellsArchives of Pharmacal Research, 27
-
I. Fidler (2003)
The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisitedNature Reviews Cancer, 3
-
A. Jemal, R. Tiwari, Taylor Murray, Asma Ghafoor, A. Samuels, Elizabeth Ward, E. Feuer, M. Thun (2004)
Cancer Statistics, 2004CA: A Cancer Journal for Clinicians, 54
-
R. Auwardt, S. Mudge, C. Chen, D. Power (2000)
Inhibition with antisense oligonucleotide suggests that IkappaB-alpha does not form a negative autoregulatory loop for NF-kappaB in mesangial cells.Experimental nephrology, 8 3
-
Guanwei Fan, Xiumei Gao, Hong Wang, Yan Zhu, Ju Zhang, Li-min Hu, Yan-fang Su, Li-Yuan Kang, Bo-li Zhang (2009)
The anti-inflammatory activities of Tanshinone IIA, an active component of TCM, are mediated by estrogen receptor activation and inhibition of iNOSThe Journal of Steroid Biochemistry and Molecular Biology, 113
-
G. Murray, M. Duncan, E. Arbuckle, W. Melvin, J. Fothergill (1998)
Matrix metalloproteinases and their inhibitors in gastric cancerGut, 43
-
V. Bours, G. Bonizzi, M. Bentires-Alj, F. Bureau, J. Piette, P. Lekeux, M. Merville (2000)
NF-κB activation in response to toxical and therapeutical agents: role in inflammation and cancer treatmentToxicology, 153
-
R. Mazzieri, L. Masiero, L. Zanetta, S. Monea, M. Onisto, S. Garbisa, P. Mignatti (1997)
Control of type IV collagenase activity by components of the urokinase–plasmin system: a regulatory mechanism with cell‐bound reactantsThe EMBO Journal, 16
-
W. Lubbe, Zengyi Zhou, W. Fu, David Zuzga, S. Schulz, R. Fridman, R. Muschel, S. Waldman, G. Pitari (2006)
Tumor Epithelial Cell Matrix Metalloproteinase 9 Is a Target for Antimetastatic Therapy in Colorectal CancerClinical Cancer Research, 12
-
A. Farina, A. Coppa, A. Tiberio, A. Tacconelli, A. Turco, Gulia Colletta, Alberto Gulino, A. Mackay (1998)
Transforming growth factor‐β1 enhances the invasiveness of human MDA‐MB‐231 breast cancer cells by up‐regulating urokinase activityInternational Journal of Cancer, 75
-
U. Jin, Seok‐jong Suh, H. Chang, J. Son, Seung Lee, K. Son, Young-Chae Chang, Cheorl-Ho Kim (2008)
Tanshinone IIA from Salvia miltiorrhiza BUNGE inhibits human aortic smooth muscle cell migration and MMP‐9 activity through AKT signaling pathwayJournal of Cellular Biochemistry, 104
-
H. Iishi, M. Tatsuta, M. Baba, H. Uehara, A. Nakaizumi, K. Shinkai, H. Akedo, H. Funai, S. Ishiguro, I. Kitagawa (1997)
Inhibition by ginsenoside Rg3 of bombesin-enhanced peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar ratsClinical & Experimental Metastasis, 15
-
K. Brew, D. Dinakarpandian, Hideaki Nagase, Hideaki Nagase (2000)
Tissue inhibitors of metalloproteinases: evolution, structure and function.Biochimica et biophysica acta, 1477 1-2
-
Haifeng Jin, Yanglin Pan, Lijie He, Hui-hong Zhai, Xiaohua Li, Lina Zhao, Li Sun, Jie Liu, L. Hong, Jiu-gang Song, Huahong Xie, Juan Gao, Shuang-yin Han, Ying Li, D. Fan (2007)
p75 Neurotrophin Receptor Inhibits Invasion and Metastasis of Gastric CancerMolecular Cancer Research, 5
-
S. Yuan, Renmin Huang, Xiu-jie Wang, Yi Song, Guang-qi Huang (1998)
Reversing effect of Tanshinone on malignant phenotypes of human hepatocarcinoma cell line.World journal of gastroenterology, 4 4
-
Haifeng Jin, Yanglin Pan, Lina Zhao, Hui-hong Zhai, Xiaohua Li, Li Sun, Lijie He, Yu Chen, L. Hong, Yu-lei Du, D. Fan (2007)
p75 neurotrophin receptor suppresses the proliferation of human gastric cancer cells.Neoplasia, 9 6
-
Hui Wang, W. Fu, J. Im, Zengyi Zhou, S. Santoro, Vandana Iyer, C. Dipersio, Qian-chun Yu, V. Quaranta, A. Al‐Mehdi, R. Muschel (2004)
Tumor cell α3β1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasisThe Journal of Cell Biology, 164
- Publisher
- Springer Journals
- Copyright
- Copyright © 2009 by CPS and SIMM
- Subject
- Biomedicine; Biomedicine, general; Pharmacology/Toxicology; Medical Microbiology; Immunology; Internal Medicine; Vaccine
- ISSN
- 1671-4083
- eISSN
- 1745-7254
- DOI
- 10.1038/aps.2009.139
- Publisher site
- See Article on Publisher Site
Abstract
Acta Pharmacologica Sinica (2009) 30: 1537–1542 npg © 2009 CPS and SIMM All rights reserved 1671-4083/09 $32.00 www.nature.com/aps Original Article Inhibitory effects of tanshinone II-A on invasion and metastasis of human colon carcinoma cells Yun-feng SHAN, Xian SHEN, Yuan-kang XIE, Ji-cai CHEN, Hong-qi SHI, Zheng-ping YU, Qi-tong SONG, Men-tao ZHOU, Qi-yu ZHANG* Department of General Surgery, the First Affiliated Hospital of Wenzhou Medical College, Wenzhou 325000, China Aim: To investigate the effects and possible mechanisms of tanshinone II-A, an alcohol extract of the root of Salvia miltiorrhiza Bunge, on tumor invasion and metastasis of human colon carcinoma (CRC) cells. Methods: The effects of tanshinone II-A on invasion and metastasis of CRC cell lines HT29 and SW480 were evaluated by in vitro and in vivo assays. Western blotting was used to investigate possible molecular mechanisms of tanshinone II-A anti-cancer actions. Results: Tanshinone II-A inhibited migration and invasion of CRC cells in a dose-dependent manner. The inhibitory effect also depended on time, with the most significant effects observed at 72 h. Tanshinone II-A also significantly inhibited in vivo metastasis of colon carcinoma SW480 cells. It inhibited in vitro and in vivo invasion and metastasis of CRC cells by reducing levels of
Journal
Acta Pharmacologica Sinica – Springer Journals
Published: Oct 12, 2009