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MiRP1 Forms IKr Potassium Channels with HERG and Is Associated with Cardiac Arrhythmia

MiRP1 Forms IKr Potassium Channels with HERG and Is Associated with Cardiac Arrhythmia UC Irvine UC Irvine Previously Published Works Title Permalink https://escholarship.org/uc/item/9269c0t1 Journal Cell, 97(2) ISSN 0092-8674 Authors Abbott, GW Sesti, F Splawski, I et al. Publication Date 1999-04-01 DOI 10.1016/s0092-8674(00)80728-x License https://creativecommons.org/licenses/by/4.0/ 4.0 Peer reviewed eScholarship.org Powered by the California Digital Library University of California Cell, Vol. 97, 175–187, April 16, 1999, Copyright 1999 by Cell Press MiRP1 Forms I Potassium Channels with HERG Kr and Is Associated with Cardiac Arrhythmia k k Geoffrey W. Abbott,* Federico Sesti,* Trudeau et al., 1995; Veldkamp et al., 1995; Ho et al., †k Igor Splawski, Marianne E. Buck,* 1996; Howarth et al., 1996; Spector et al., 1996a; Wang ‡ † Michael H. Lehmann, Katherine W. Timothy, et al., 1997b; Zou et al., 1997; Ho et al., 1998; Zhou et † § Mark T. Keating, and Steve A. N. Goldstein* al., 1998). This led to the hypothesis that HERG might * Departments of Pediatrics and assemble with an additional subunit to form native I Kr Cellular and Molecular Physiology channels (Sanguinetti et al., 1995). Here, we describe Boyer Center for Molecular Medicine MinK-related peptide 1 (MiRP1), a subunit of 123 amino Yale University School of Medicine acids and a single predicted transmembrane segment. New http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Cell Unpaywall

MiRP1 Forms IKr Potassium Channels with HERG and Is Associated with Cardiac Arrhythmia

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0092-8674
DOI
10.1016/s0092-8674(00)80728-x
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Abstract

UC Irvine UC Irvine Previously Published Works Title Permalink https://escholarship.org/uc/item/9269c0t1 Journal Cell, 97(2) ISSN 0092-8674 Authors Abbott, GW Sesti, F Splawski, I et al. Publication Date 1999-04-01 DOI 10.1016/s0092-8674(00)80728-x License https://creativecommons.org/licenses/by/4.0/ 4.0 Peer reviewed eScholarship.org Powered by the California Digital Library University of California Cell, Vol. 97, 175–187, April 16, 1999, Copyright 1999 by Cell Press MiRP1 Forms I Potassium Channels with HERG Kr and Is Associated with Cardiac Arrhythmia k k Geoffrey W. Abbott,* Federico Sesti,* Trudeau et al., 1995; Veldkamp et al., 1995; Ho et al., †k Igor Splawski, Marianne E. Buck,* 1996; Howarth et al., 1996; Spector et al., 1996a; Wang ‡ † Michael H. Lehmann, Katherine W. Timothy, et al., 1997b; Zou et al., 1997; Ho et al., 1998; Zhou et † § Mark T. Keating, and Steve A. N. Goldstein* al., 1998). This led to the hypothesis that HERG might * Departments of Pediatrics and assemble with an additional subunit to form native I Kr Cellular and Molecular Physiology channels (Sanguinetti et al., 1995). Here, we describe Boyer Center for Molecular Medicine MinK-related peptide 1 (MiRP1), a subunit of 123 amino Yale University School of Medicine acids and a single predicted transmembrane segment. New

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Cell – Unpaywall

Published: Apr 1, 1999

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