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Human metallothionein genes—primary structure of the metallothionein-II gene and a related processed gene

Human metallothionein genes—primary structure of the metallothionein-II gene and a related... The complete nucleotide sequence of two of the human metallothionein gene family has been compared. One is a functional metallothionein-II gene, the other a pseudogene, lacking introns, terminating in a poly(A) tail and flanked by two direct repeats. In addition, we have detected a size polymorphism associated with the processed gene in the population examined, and we have observed a region of apparent secondary structure homology between a 5′ flanking region of the functional metallothionein-II gene and that of a mouse metallothionein-I gene. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nature Springer Journals

Human metallothionein genes—primary structure of the metallothionein-II gene and a related processed gene

Nature , Volume 299 (5886) – Oct 28, 1982

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References (37)

Publisher
Springer Journals
Copyright
Copyright © 1982 by Nature Publishing Group
Subject
Science, Humanities and Social Sciences, multidisciplinary; Science, Humanities and Social Sciences, multidisciplinary; Science, multidisciplinary
ISSN
0028-0836
eISSN
1476-4687
DOI
10.1038/299797a0
Publisher site
See Article on Publisher Site

Abstract

The complete nucleotide sequence of two of the human metallothionein gene family has been compared. One is a functional metallothionein-II gene, the other a pseudogene, lacking introns, terminating in a poly(A) tail and flanked by two direct repeats. In addition, we have detected a size polymorphism associated with the processed gene in the population examined, and we have observed a region of apparent secondary structure homology between a 5′ flanking region of the functional metallothionein-II gene and that of a mouse metallothionein-I gene.

Journal

NatureSpringer Journals

Published: Oct 28, 1982

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