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The complete nucleotide sequence of two of the human metallothionein gene family has been compared. One is a functional metallothionein-II gene, the other a pseudogene, lacking introns, terminating in a poly(A) tail and flanked by two direct repeats. In addition, we have detected a size polymorphism associated with the processed gene in the population examined, and we have observed a region of apparent secondary structure homology between a 5′ flanking region of the functional metallothionein-II gene and that of a mouse metallothionein-I gene.
Nature – Springer Journals
Published: Oct 28, 1982
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