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Tumor‐associated tissue eosinophilia in nasopharyngeal carcinoma. A pathologic study of 422 primary and 138 metastatic tumors

Tumor‐associated tissue eosinophilia in nasopharyngeal carcinoma. A pathologic study of 422... A study of biopsy specimens from 422 consecutive primary nasopharyngeal carcinomas (NPCs) revealed tumor‐associated tissue eosinophilia (TATE) in a large proportion (26%) of the tumors. TATE occurred more frequently in nonkeratinizing carcinomas (NKC, 38%) than in the squamous (21%) or undifferentiated (23%) types. There was no sex predilection and no association with the presence of intratumor amyloid deposits. Stromal eosinophilia was also observed in 53 (38%) of 138 metastatic NPCs in lymph nodes, where it had occasionally led to confusion with Hodgkin's disease. TATE may be a feature of diagnostic importance in NPC, although its prognostic significance remains to be ascertained. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Cancer Wiley

Tumor‐associated tissue eosinophilia in nasopharyngeal carcinoma. A pathologic study of 422 primary and 138 metastatic tumors

Looi, Lai‐Meng
Cancer , Volume 59 (3) – Feb 1, 1987
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References (23)

Publisher
Wiley
Copyright
Copyright © 1987 American Cancer Society
ISSN
0008-543X
eISSN
1097-0142
DOI
10.1002/1097-0142(19870201)59:3<466::AID-CNCR2820590319>3.0.CO;2-P
Publisher site
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Abstract

A study of biopsy specimens from 422 consecutive primary nasopharyngeal carcinomas (NPCs) revealed tumor‐associated tissue eosinophilia (TATE) in a large proportion (26%) of the tumors. TATE occurred more frequently in nonkeratinizing carcinomas (NKC, 38%) than in the squamous (21%) or undifferentiated (23%) types. There was no sex predilection and no association with the presence of intratumor amyloid deposits. Stromal eosinophilia was also observed in 53 (38%) of 138 metastatic NPCs in lymph nodes, where it had occasionally led to confusion with Hodgkin's disease. TATE may be a feature of diagnostic importance in NPC, although its prognostic significance remains to be ascertained.

Journal

Cancer – Wiley

Published: Feb 1, 1987

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