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A Longitudinal Twin Study of Fears From Middle Childhood to Early Adulthood

A Longitudinal Twin Study of Fears From Middle Childhood to Early Adulthood ORIGINAL ARTICLE A Longitudinal Twin Study of Fears From Middle Childhood to Early Adulthood Evidence for a Developmentally Dynamic Genome Kenneth S. Kendler, MD; Charles O. Gardner, PhD; Peter Annas, PhD; Michael C. Neale, PhD; Lindon J. Eaves, PhD, DSc; Paul Lichtenstein, PhD Context: While the nature of common fears changes over For all 3 fears, the best-fit model revealed develop- development, we do not know whether genetic effects mentally dynamic effects and, in particular, evidence on fear-proneness are developmentally stable or devel- for both genetic attenuation and innovation. That is, opmentally dynamic. genetic factors influencing fear intensity at age 8 to 9 years decline substantially in importance over time. Objective: To determine the temporal pattern of ge- Furthermore, new sets of genetic risk factors impact- netic and environmental effects on the level of intensity ing fear intensity “come on line” in early adolescence, of common fears. late adolescence, and early adulthood. As the twins aged, the influence of the shared environment Design: Prospective, 4-wave longitudinal twin study. declined and unique environment increased. No sex Structural modeling was performed with Mx. effects were found for situational fears while for ani- mal and blood/injury fears, genetic factors in males Setting: http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Psychiatry American Medical Association

A Longitudinal Twin Study of Fears From Middle Childhood to Early Adulthood

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References (51)

Publisher
American Medical Association
Copyright
Copyright 2008 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-622X
eISSN
2168-6238
DOI
10.1001/archpsyc.65.4.421
pmid
18391130
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL ARTICLE A Longitudinal Twin Study of Fears From Middle Childhood to Early Adulthood Evidence for a Developmentally Dynamic Genome Kenneth S. Kendler, MD; Charles O. Gardner, PhD; Peter Annas, PhD; Michael C. Neale, PhD; Lindon J. Eaves, PhD, DSc; Paul Lichtenstein, PhD Context: While the nature of common fears changes over For all 3 fears, the best-fit model revealed develop- development, we do not know whether genetic effects mentally dynamic effects and, in particular, evidence on fear-proneness are developmentally stable or devel- for both genetic attenuation and innovation. That is, opmentally dynamic. genetic factors influencing fear intensity at age 8 to 9 years decline substantially in importance over time. Objective: To determine the temporal pattern of ge- Furthermore, new sets of genetic risk factors impact- netic and environmental effects on the level of intensity ing fear intensity “come on line” in early adolescence, of common fears. late adolescence, and early adulthood. As the twins aged, the influence of the shared environment Design: Prospective, 4-wave longitudinal twin study. declined and unique environment increased. No sex Structural modeling was performed with Mx. effects were found for situational fears while for ani- mal and blood/injury fears, genetic factors in males Setting:

Journal

JAMA Psychiatry – American Medical Association

Published: Apr 1, 2008

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