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Recent advancements in ring closing olefin metathesis

Recent advancements in ring closing olefin metathesis A short overview on recent developments in ring closing metathesis (RCM) of 1,ω-dienes to cycloalkenes is provided, with particular emphasis on applications to natural product synthesis and the preparation of olfactory perfume ingredients. These examples show that RCM is becoming a mature tool for the formation of carbo– and heterocycles of any size ⩾ 5, including medium and large ring compounds which are difficult to prepare otherwise. Although the reactivity profile of the standard metathesis (pre)catalysts cannot be reduced to a simplistic picture, their excellent compatibility with an array of functional groups will be outlined. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Topics in Catalysis Springer Journals

Recent advancements in ring closing olefin metathesis

Topics in Catalysis , Volume 4 (4) – Sep 30, 2004

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References (72)

Publisher
Springer Journals
Copyright
Copyright © 1997 by Kluwer Academic Publishers
Subject
Chemistry; Catalysis; Physical Chemistry; Pharmacy; Industrial Chemistry/Chemical Engineering; Characterization and Evaluation of Materials
ISSN
1022-5528
eISSN
1572-9028
DOI
10.1023/A:1019117012154
Publisher site
See Article on Publisher Site

Abstract

A short overview on recent developments in ring closing metathesis (RCM) of 1,ω-dienes to cycloalkenes is provided, with particular emphasis on applications to natural product synthesis and the preparation of olfactory perfume ingredients. These examples show that RCM is becoming a mature tool for the formation of carbo– and heterocycles of any size ⩾ 5, including medium and large ring compounds which are difficult to prepare otherwise. Although the reactivity profile of the standard metathesis (pre)catalysts cannot be reduced to a simplistic picture, their excellent compatibility with an array of functional groups will be outlined.

Journal

Topics in CatalysisSpringer Journals

Published: Sep 30, 2004

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