Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/wiley/antiapoptotic-effect-of-found-in-inflammatory-zone-fizz-1-on-mouse-IZqUtZhbgg
References (34)
-
M. Nair, D. Cochrane, J. Allen (2003)
Macrophages in chronic type 2 inflammation have a novel phenotype characterized by the abundant expression of Ym1 and Fizz1 that can be partly replicated in vitro.Immunology letters, 85 2
-
L. Allan, N. Morrice, Suzanne Brady, G. Magee, Shalini Pathak, P. Clarke (2003)
Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPKNature Cell Biology, 5
-
Jessica Tashker, Michael Olson, S. Kornbluth (2002)
Post-cytochrome C protection from apoptosis conferred by a MAPK pathway in Xenopus egg extracts.Molecular biology of the cell, 13 2
-
Q. Tong, Liduan Zheng, Qiaohua Kang, J. Dodd-o, J. Langer, Bo Li, Danming Wang, Dechun Li (2006)
Upregulation of hypoxia‐induced mitogenic factor in bacterial lipopolysaccharide‐induced acute lung injuryFEBS Letters, 580
-
H. Zhang, M. Gharaee-Kermani, S. Phan (1997)
Regulation of lung fibroblast alpha-smooth muscle actin expression, contractile phenotype, and apoptosis by IL-1beta.Journal of immunology, 158 3
-
B. Santiago, M. Galindo, G. Palao, J. Pablos (2004)
Intracellular Regulation of Fas-Induced Apoptosis in Human Fibroblasts by Extracellular Factors and Cycloheximide 1The Journal of Immunology, 172
-
A. Desmoulire, M. Redard, I. Darby, G. Gabbiani (1995)
Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar.The American journal of pathology, 146 1
-
Tianju Liu, S. Dhanasekaran, Hong Jin, Biao Hu, S. Tomlins, A. Chinnaiyan, S. Phan (2004)
FIZZ1 stimulation of myofibroblast differentiation.The American journal of pathology, 164 4
-
M. Rytömaa, K. Lehmann, J. Downward (2000)
Matrix detachment induces caspase-dependent cytochrome c release from mitochondria: inhibition by PKB/Akt but not Raf signallingOncogene, 19
-
M. Gall, J. Chambard, J. Breittmayer, D. Grall, J. Pouysségur, E. Obberghen-Schilling (2000)
The p42/p44 MAP kinase pathway prevents apoptosis induced by anchorage and serum removal.Molecular biology of the cell, 11 3
-
D. Roymans, H. Slegers (2001)
Phosphatidylinositol 3-kinases in tumor progression.European journal of biochemistry, 268 3
-
G. Raes, P. Baetselier, W. Noël, A. Beschin, F. Brombacher, Gholamreza Gh. (2002)
Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophagesJournal of Leukocyte Biology, 71
-
Kazuyo Yamaji-Kegan, Qingning Su, Daniel Angelini, H. Champion, R. Johns (2006)
Hypoxia-induced mitogenic factor has proangiogenic and proinflammatory effects in the lung via VEGF and VEGF receptor-2.American journal of physiology. Lung cellular and molecular physiology, 291 6
-
X. Teng, Dechun Li, H. Champion, R. Johns (2003)
FIZZ1/RELM&agr;, a Novel Hypoxia-Induced Mitogenic Factor in Lung With Vasoconstrictive and Angiogenic PropertiesCirculation Research: Journal of the American Heart Association, 92
-
Juliane Fluck, C. Querfeld, Anja Cremer, S. Niland, T. Krieg, S. Sollberg (1998)
Normal human primary fibroblasts undergo apoptosis in three-dimensional contractile collagen gels.The Journal of investigative dermatology, 110 2
-
Z. Xia, M. Dickens, J. Raingeaud, R. Davis, M. Greenberg (1995)
Opposing Effects of ERK and JNK-p38 MAP Kinases on ApoptosisScience, 270
-
Ilona Holcomb, R. Kabakoff, B. Chan, Thad Baker, A. Gurney, W. Henzel, C. Nelson, H. Lowman, Barbara Wright, N. Skelton, G. Frantz, D. Tumas, F. Peale, D. Shelton, C. Hébert (2000)
FIZZ1, a novel cysteine‐rich secreted protein associated with pulmonary inflammation, defines a new gene familyThe EMBO Journal, 19
-
I. Darby, O. Skalli, G. Gabbiani (1990)
Alpha-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing.Laboratory investigation; a journal of technical methods and pathology, 63 1
-
A. Jelaska, J. Korn (2000)
Role of apoptosis and transforming growth factor beta1 in fibroblast selection and activation in systemic sclerosis.Arthritis and rheumatism, 43 10
-
S. Datta, A. Brunet, M. Greenberg (1999)
Cellular survival: a play in three Akts.Genes & development, 13 22
-
J. MacKeigan, Timothy Collins, J. Ting (2000)
MEK Inhibition Enhances Paclitaxel-induced Tumor Apoptosis*The Journal of Biological Chemistry, 275
-
A. Kushiyama, N. Shojima, T. Ogihara, K. Inukai, H. Sakoda, M. Fujishiro, Y. Fukushima, M. Anai, Hiraku Ono, N. Horike, A. Viana, Y. Uchijima, Koichi Nishiyama, T. Shimosawa, T. Fujita, H. Katagiri, Y. Oka, H. Kurihara, T. Asano (2005)
Resistin-like Molecule β Activates MAPKs, Suppresses Insulin Signaling in Hepatocytes, and Induces Diabetes, Hyperlipidemia, and Fatty Liver in Transgenic Mice on a High Fat Diet*Journal of Biological Chemistry, 280
-
C. Steppan, Elizabeth Brown, C. Wright, Savitha Bhat, Ronadip Banerjee, C. Dai, Gregory Enders, D. Silberg, X. Wen, Gary Wu, M. Lazar (2001)
A family of tissue-specific resistin-like molecules.Proceedings of the National Academy of Sciences of the United States of America, 98 2
-
Q. Tong, Liduan Zheng, Li Lin, Danming Wang, Dechun Li (2006)
Hypoxia-Induced Mitogenic Factor Promotes Vascular Adhesion Molecule-1 Expression via the PI-3K/Akt–NF- (cid:2) B Signaling Pathway -
K. Wagner, A. Hellberg, Susan Balenger, R. Depping, J. Dodd-o, R. Johns, Dechun Li (2004)
Hypoxia-induced mitogenic factor has antiapoptotic action and is upregulated in the developing lung: coexpression with hypoxia-inducible factor-2alpha.American journal of respiratory cell and molecular biology, 31 3
-
C. Kuhn, J. McDonaldt (1991)
The roles of the myofibroblast in idiopathic pulmonary fibrosis. Ultrastructural and immunohistochemical features of sites of active extracellular matrix synthesis.The American journal of pathology, 138 5
-
John Kerr, A. Wyllie, R. Alastair, Currie (1972)
Apoptosis: A Basic Biological Phenomenon with Wide-ranging Implications in Tissue KineticsBritish Journal of Cancer, 26
-
G. Majno, G. Gabbiani, B. Hirschel, Ryan Gb, P. Statkov (1971)
Contraction of Granulation Tissue in vitro: Similarity to Smooth MuscleScience, 173
-
H. Zhang, S. Phan (1999)
Inhibition of Myofibroblast Apoptosis by Transforming Growth Factor β1American Journal of Respiratory Cell and Molecular Biology, 21
-
Tianju Liu, Hong-xing Jin, M. Ullenbruch, Biao Hu, N. Hashimoto, B. Moore, A. McKenzie, N. Lukacs, S. Phan (2004)
Regulation of Found in Inflammatory Zone 1 Expression in Bleomycin-Induced Lung Fibrosis: Role of IL-4/IL-13 and Mediation via STAT-61The Journal of Immunology, 173
-
J. Downward (1998)
Mechanisms and consequences of activation of protein kinase B/Akt.Current opinion in cell biology, 10 2
-
Hong-Yu Zhang, S. Phan (1999)
Inhibition of myofibroblast apoptosis by transforming growth factor beta(1).American journal of respiratory cell and molecular biology, 21 6
-
S. Phan, J. Varani, D. Smith (1985)
Rat lung fibroblast collagen metabolism in bleomycin-induced pulmonary fibrosis.The Journal of clinical investigation, 76 1
-
Bernhard Gerstmayer, D. Küsters, Stephan Gebel, Thomas Müller, E. Miert, Kay Hofmann, Andreas Bosio (2003)
Identification of RELMgamma, a novel resistin-like molecule with a distinct expression pattern.Genomics, 81 6
- Publisher
- Wiley
- Copyright
- Copyright © 2007 Wiley Subscription Services
- ISSN
- 0022-3417
- eISSN
- 1096-9896
- DOI
- 10.1002/path.2161
- pmid
- 17492827
- Publisher site
- See Article on Publisher Site
Abstract
Myofibroblasts play an essential role in the abnormal deposition of extracellular matrix in pulmonary fibrosis. The presence or prolonged survival of these cells may be a key factor in the pathogenesis of progressive pulmonary fibrosis. Found in inflammatory zone (FIZZ)1 can induce myofibroblast differentiation and has an antiapoptotic effect on embryonic lung explant cultures. In this study, we investigated whether FIZZ1 also has an antiapoptotic effect on mouse lung fibroblasts (MLFs). Cells were treated with FIZZ1 for 24 h and then apoptosis was induced by TNFα in the presence of cycloheximide (CHX). FIZZ1 exhibited an antiapoptotic effect in MLFs, as assessed by flow cytometric analysis and TUNEL staining. Moreover, the cell number was higher in the FIZZ1‐treated group relative to the non‐treated control group after treatment with TNFα and CHX. FIZZ1 treatment also inhibited the apoptotic agent‐induced activities of caspase‐3 and caspase‐8. Examination of potential signalling pathways revealed that FIZZ1 induced rapid phosphorylation of ERK‐1/2, while PD98059, a MEK/ERK inhibitor, markedly induced activation of caspase‐3. This anti‐apoptotic effect of FIZZ1 was associated with induction of myofibroblast differentiation in response to FIZZ1 stimulation. Taken together, these findings suggest that FIZZ1 is involved in pulmonary fibrosis through both induction of myofibroblast differentiation and increased or prolonged survival of myofibroblasts. This effect of FIZZ1 was mediated by inhibition of caspase‐3 and ‐8, with involvement of the ERK pathway. Copyright © 2007 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
Journal
The Journal of Pathology – Wiley
Published: Jan 1, 2007
Keywords: ; ; ; ; ;