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In vitro immunosuppressive activity of soluble HLA class I and Fas ligand molecules:do they play a role in autologous blood transfusion?

In vitro immunosuppressive activity of soluble HLA class I and Fas ligand molecules:do they play... BACKGROUND: The immunomodulatory effects of allogeneic blood transfusion may contribute to a poor prognosis in patients with cancer who are undergoing surgery, and clinical trials have been carried out to investigate whether these patients would benefit from autologous blood donation. As the immunomodulatory effects of allogeneic blood transfusion have been related to soluble molecules released from residual WBCs during storage, the in vitro immunomodulatory activity of soluble molecules detected in supernatants from stored autologous blood was evaluated. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Transfusion Wiley

In vitro immunosuppressive activity of soluble HLA class I and Fas ligand molecules:do they play a role in autologous blood transfusion?

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References (61)

Publisher
Wiley
Copyright
Copyright © 2001 Wiley Subscription Services
ISSN
0041-1132
eISSN
1537-2995
DOI
10.1046/j.1537-2995.2001.41080988.x
Publisher site
See Article on Publisher Site

Abstract

BACKGROUND: The immunomodulatory effects of allogeneic blood transfusion may contribute to a poor prognosis in patients with cancer who are undergoing surgery, and clinical trials have been carried out to investigate whether these patients would benefit from autologous blood donation. As the immunomodulatory effects of allogeneic blood transfusion have been related to soluble molecules released from residual WBCs during storage, the in vitro immunomodulatory activity of soluble molecules detected in supernatants from stored autologous blood was evaluated.

Journal

TransfusionWiley

Published: Jan 1, 2001

Keywords: ; ; ; ; ; ; ; ; ; ; ; ; ; ;

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