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Frailty as a Risk Factor for Chronic Sinusitis: Insights from a Nationwide Cross‐sectional Survey

Frailty as a Risk Factor for Chronic Sinusitis: Insights from a Nationwide Cross‐sectional Survey INTRODUCTIONWith the continuous advancements in health care and the extension of life expectancy, the proportion of elderly individuals within the general population is progressively increasing. This trend has raised concerns in the public health sector regarding the increased vulnerability to frailty and susceptibility to chronic inflammatory diseases associated with aging.1 Recent studies have demonstrated that the prevalence of chronic rhinosinusitis (CRS) varies with age, particularly among the older adults, where it stands at approximately 6.55%, significantly higher than in younger populations,2 making CRS the sixth most common chronic disease among the elderly.3 It is projected that by 2050, the global population aged 65 and older will double to 1.5 billion, which could substantially raise the economic burden of chronic sinusitis on health care systems.4 Therefore, a thorough understanding of the disease characteristics in elderly patients with age‐related CRS is crucial for clinicians.5Frailty, characterized by reduced physiological reserves and multi‐system dysfunction leading to diminished capacity for maintaining homeostasis and responding to internal and external stressors,6 was initially delineated within geriatric populations. Since then, the definition of frailty has expanded and is now viewed as a risk factor for a variety of adverse health outcomes, including the risk of morbidity and mortality http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Laryngoscope Wiley

Frailty as a Risk Factor for Chronic Sinusitis: Insights from a Nationwide Cross‐sectional Survey

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References (34)

Publisher
Wiley
Copyright
© 2025 The American Laryngological, Rhinological and Otological Society, Inc.
ISSN
0023-852X
eISSN
1531-4995
DOI
10.1002/lary.31924
Publisher site
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Abstract

INTRODUCTIONWith the continuous advancements in health care and the extension of life expectancy, the proportion of elderly individuals within the general population is progressively increasing. This trend has raised concerns in the public health sector regarding the increased vulnerability to frailty and susceptibility to chronic inflammatory diseases associated with aging.1 Recent studies have demonstrated that the prevalence of chronic rhinosinusitis (CRS) varies with age, particularly among the older adults, where it stands at approximately 6.55%, significantly higher than in younger populations,2 making CRS the sixth most common chronic disease among the elderly.3 It is projected that by 2050, the global population aged 65 and older will double to 1.5 billion, which could substantially raise the economic burden of chronic sinusitis on health care systems.4 Therefore, a thorough understanding of the disease characteristics in elderly patients with age‐related CRS is crucial for clinicians.5Frailty, characterized by reduced physiological reserves and multi‐system dysfunction leading to diminished capacity for maintaining homeostasis and responding to internal and external stressors,6 was initially delineated within geriatric populations. Since then, the definition of frailty has expanded and is now viewed as a risk factor for a variety of adverse health outcomes, including the risk of morbidity and mortality

Journal

The Laryngoscope – Wiley

Published: May 1, 2025

Keywords: chronic rhinosinusitis; frailty; population‐based survey

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