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a,b a,b Samuel R. Chamberlain and Barbara J. Sahakian Purpose of review Abbreviations Impulsive symptoms occur across neuropsychiatric ADHD attention deficit hyperactivity disorder DSM-IV Diagnostic and Statistical Manual of Mental Disorders version IV disorders, with important ramifications for everyday OCD obsessive – compulsive disorder functioning and quality of life. This article considers recent RIFG right inferior frontal gyrus developments in the neuropsychological assessment of impulsivity with a focus on the ability to suppress motor 2007 Lippincott Williams & Wilkins responses (response inhibition). 0951-7367 Recent findings Using objective tests, response inhibition deficits were identified in several neuropsychiatric conditions associated Introduction with impulsivity, namely attention deficit hyperactivity The term ‘impulsivity’ encompasses a multitude of disorder, trichotillomania, obsessive – compulsive disorder, behaviours or responses that are poorly conceived, and chronic substance abuse. Deficits were also found in premature, inappropriate, and that frequently result in unaffected first-degree relatives of attention deficit unwanted or deleterious outcomes [1]. We all engage hyperactivity disorder and obsessive – compulsive disorder from time to time in impulsive acts, such as blurting out patients. Evidence from patients with focal brain lesions and critical comments without thinking, or buying expens- from healthy volunteers using functional MRI and ive items on
Current Opinion in Psychiatry – Wolters Kluwer Health
Published: May 1, 2007
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