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Human fascioliasis successfully treated with triclabendazole

Human fascioliasis successfully treated with triclabendazole Fascioliasis, caused by the common liver fluke Fusciolu hepatica, is an endemic infection in sheep and cattle in many parts of Australia. Infections in humans in Australia have been reported infrequently and the most appropriate therapy for human fascioliasis remains to be determined. This case report describes a patient with the infection unsuccessfully treated with multiple high doses of praziquantel, mebendazole or albendazole. The infection was successfully eliminated by the administration of triclabendazole in two single doses of 900 mg (12 mg/kg) two days apart. No side effects were observed after the treatment. Based on our experience and that recently reported in the literature, triclabendazole may be regarded as the drug of choice for the treatment of human fascioliasis. (Aust NZ J Med 1992; 22: 45–47.) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Internal Medicine Journal Wiley

Human fascioliasis successfully treated with triclabendazole

Laird, P. P.; Boray, J. C.
Internal Medicine Journal , Volume 22 (1) – Feb 1, 1992
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References (26)

Publisher
Wiley
Copyright
Copyright © 1992 Wiley Subscription Services, Inc., A Wiley Company
ISSN
1444-0903
eISSN
1445-5994
DOI
10.1111/j.1445-5994.1992.tb01708.x
Publisher site
See Article on Publisher Site

Abstract

Fascioliasis, caused by the common liver fluke Fusciolu hepatica, is an endemic infection in sheep and cattle in many parts of Australia. Infections in humans in Australia have been reported infrequently and the most appropriate therapy for human fascioliasis remains to be determined. This case report describes a patient with the infection unsuccessfully treated with multiple high doses of praziquantel, mebendazole or albendazole. The infection was successfully eliminated by the administration of triclabendazole in two single doses of 900 mg (12 mg/kg) two days apart. No side effects were observed after the treatment. Based on our experience and that recently reported in the literature, triclabendazole may be regarded as the drug of choice for the treatment of human fascioliasis. (Aust NZ J Med 1992; 22: 45–47.)

Journal

Internal Medicine Journal – Wiley

Published: Feb 1, 1992

Keywords: ; ;

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