Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 7-Day Trial for You or Your Team.

Learn More →

Sensitivity and Specificity of Memory Dysfunction in Schizophrenia: A Comparison With Major Depression

Sensitivity and Specificity of Memory Dysfunction in Schizophrenia: A Comparison With Major... Fifty-three schizophrenic subjects were compared to 50 patients with major depression and 50 normal controls on measures of working memory, declarative memory and malingering. The schizophrenic group scored 1–2 SDs below controls on all measures, while depressive patients exposed only lesser deficits in working memory and free recall. The memory deficit of the schizophrenic subjects was disproportionately greater than their intellectual decline. Differences between clinical groups could not be explained by differences in IQ, clinical symptom load or demographic characteristics. This indicates that impaired memory is a particular sensitive symptom of schizophrenia and that the impairment is specific to the illness. Working memory failure was prominent in both clinical groups. The schizophrenic subjects displayed primarily an acquisition failure, while the depressed group showed retrieval difficulties. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Clinical and Experimental Neuropsychology Taylor & Francis

Sensitivity and Specificity of Memory Dysfunction in Schizophrenia: A Comparison With Major Depression

15 pages

Loading next page...
 
/lp/taylor-francis/sensitivity-and-specificity-of-memory-dysfunction-in-schizophrenia-a-QDwrCsm0c0

References (70)

Publisher
Taylor & Francis
Copyright
Copyright Taylor & Francis Group, LLC
ISSN
1744-411x
eISSN
1380-3395
DOI
10.1076/jcen.25.1.79.13630
pmid
12607174
Publisher site
See Article on Publisher Site

Abstract

Fifty-three schizophrenic subjects were compared to 50 patients with major depression and 50 normal controls on measures of working memory, declarative memory and malingering. The schizophrenic group scored 1–2 SDs below controls on all measures, while depressive patients exposed only lesser deficits in working memory and free recall. The memory deficit of the schizophrenic subjects was disproportionately greater than their intellectual decline. Differences between clinical groups could not be explained by differences in IQ, clinical symptom load or demographic characteristics. This indicates that impaired memory is a particular sensitive symptom of schizophrenia and that the impairment is specific to the illness. Working memory failure was prominent in both clinical groups. The schizophrenic subjects displayed primarily an acquisition failure, while the depressed group showed retrieval difficulties.

Journal

Journal of Clinical and Experimental NeuropsychologyTaylor & Francis

Published: Feb 1, 2003

There are no references for this article.