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Effects of age on dopamine and serotonin receptors measured by positron tomography in the living human brain.

Effects of age on dopamine and serotonin receptors measured by positron tomography in the living... D2 dopamine and S2 serotonin receptors were imaged and measured in healthy human subjects by positron emission tomography after intravenous injection of 11C-labeled 3-N-methylspiperone. Levels of receptor in the caudate nucleus, putamen, and frontal cerebral cortex declined over the age span studied (19 to 73 years). The decline in D2 receptor in males was different from that in females. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Science (New York, N.Y.) Pubmed

Effects of age on dopamine and serotonin receptors measured by positron tomography in the living human brain.

Wong, D F; Wagner, H N; Dannals, R F; Links, J M; Frost, J J; Ravert, H T; Wilson, A A; Rosenbaum, A E; Gjedde, A; Douglass, K H
Science (New York, N.Y.) , Volume 226 (4681): -1386 – Jan 17, 1985
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Effects of age on dopamine and serotonin receptors measured by positron tomography in the living human brain.


Abstract

D2 dopamine and S2 serotonin receptors were imaged and measured in healthy human subjects by positron emission tomography after intravenous injection of 11C-labeled 3-N-methylspiperone. Levels of receptor in the caudate nucleus, putamen, and frontal cerebral cortex declined over the age span studied (19 to 73 years). The decline in D2 receptor in males was different from that in females.

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ISSN
0036-8075
DOI
10.1126/science.6334363
pmid
6334363

Abstract

D2 dopamine and S2 serotonin receptors were imaged and measured in healthy human subjects by positron emission tomography after intravenous injection of 11C-labeled 3-N-methylspiperone. Levels of receptor in the caudate nucleus, putamen, and frontal cerebral cortex declined over the age span studied (19 to 73 years). The decline in D2 receptor in males was different from that in females.

Journal

Science (New York, N.Y.) – Pubmed

Published: Jan 17, 1985

There are no references for this article.