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Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens

Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response... How neutrophils clear hyphae and other pathogens that are too large to be ingested by phagocytosis has remained unknown. Papayannopoulos et al. show that neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nature Immunology Springer Journals

Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens

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References (61)

Publisher
Springer Journals
Copyright
Copyright © 2014 by Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.
Subject
Biomedicine; Biomedicine, general; Immunology; Infectious Diseases
ISSN
1529-2908
eISSN
1529-2916
DOI
10.1038/ni.2987
Publisher site
See Article on Publisher Site

Abstract

How neutrophils clear hyphae and other pathogens that are too large to be ingested by phagocytosis has remained unknown. Papayannopoulos et al. show that neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens.

Journal

Nature ImmunologySpringer Journals

Published: Sep 14, 2014

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