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Article in press - uncorrected proof Clin Chem Lab Med 2005;43(9):893896 2005 by Walter de Gruyter · Berlin · New York. DOI 10.1515/CCLM.2005.152 2005/283 Editorial Over the last 20 years laboratory medicine has played an increasingly dominant role in clinical decisionmaking and patient management. Laboratory tests are essential to safeguarding health, screening for disease, making a diagnosis and monitoring patients (1). With the constant development of more complex tests, medical practice will become increasingly dependent on laboratory medicine (2), and this process will be underpinned by the forthcoming translation into clinical practice of new insights from promising research areas such as genomics, transcriptomics, proteomics and other ``omics'', particularly for achieving an early diagnosis and ``personalized medicine'' (3). However, laboratory tests and data are useful only if translated into clinical information that can be used effectively by physicians to improve clinical reasoning and patient management (4). The effectiveness of laboratory tests must therefore be evaluated and measured on the basis of the clinical benefit they provide in terms of an improved diagnostic process and/or therapeutic strategy, with consequent maximization of the overall health outcome. A growing body of evidence collected in recent years demonstrates inappropriateness in test requesting, interpretation
Clinical Chemistry and Laboratory Medicine (CCLM) – de Gruyter
Published: Sep 1, 2005
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