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/lp/karger/effects-of-volume-expansion-with-fluosol-da-on-renal-function-of-the-YN7Wy8SA2c
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- Publisher
- Karger
- Copyright
- © 1984 S. Karger AG, Basel
- ISSN
- 1420-4096
- eISSN
- 1423-0143
- DOI
- 10.1159/000172953
- Publisher site
- See Article on Publisher Site
Abstract
The renal responses to an intravenous infusion of a high O<sub>2</sub> affinity fluorocarbon equal to 15% of the estimated blood volume was determined in 5 monkeys and 1 baboon. In response to the infusion, blood pressure, renal plasma flow and glomerular filtration rate did not change significantly while heart rate and central venous pressure increased transiently. Significant increases in sodium and potassium excretion and osmolal and free-water clearances occurred. The renal responses to Fluosol-DA (20%) mimic in general those observed when blood volume is expanded with isotonic isooncotic dextran solutions.
Journal
Kidney and Blood Pressure Research – Karger
Published: Jan 1, 2008
Keywords: Renal function; Fluorocarbons; Volume expansion