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Eur J Nutr (2016) 55:183–195 DOI 10.1007/s00394-015-0836-y ORIGINAL CONTRIBUTION Effects of increased wholegrain consumption on immune and inflammatory markers in healthy low habitual wholegrain consumers Antonios Ampatzoglou · Charlotte L. Williams · Kiranjit K. Atwal · Catherine M. Maidens · Alastair B. Ross · Frank Thielecke · Satya S. Jonnalagadda · Orla B. Kennedy · Parveen Yaqoob Received: 13 August 2014 / Accepted: 12 January 2015 / Published online: 25 January 2015 © Springer-Verlag Berlin Heidelberg 2015 Abstract products, with compliance verified by analysis of plasma Purpose Wholegrain (WG) consumption is associated alkylresorcinols (ARs). with reduced risk of cardiovascular disease, but clinical Results On the WG intervention, WG consumption data on inflammation and immune function is either con - reached 168 g/day (P < 0.001), accompanied by an increase flicting or limited. The objective of this study was to assess in plasma ARs (P < 0.001) and fibre intake ( P < 0.001), the impact of increasing WG consumption to at least 80 g/ without affecting other aspects of dietary intake. On the day on markers of inflammation and glucose metabolism WG arm, there were trends for lower ex vivo activation and on phenotypic and functional aspects of the
European Journal of Nutrition – Springer Journals
Published: Jan 25, 2015
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