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Prognostic value of tumor “budding” in patients with colorectal cancer

Prognostic value of tumor “budding” in patients with colorectal cancer Diseases of the Volume Number 36 Comx REcrvM 7 JULY 1993 ORIGINAL CONTRIBUTIONS Prognostic Value of Tumor "Budding" in Patients with Colorectal Cancer Kazuo Hase, M.D.,* Clayton Shatney, M.D.,J- Denise Johnson, M.D.,J- Michael Trollope, M.D.,:~ Mark Vierra, M.D.-~ From the Departments of Surgery, *National Defense Medical College, Saitama, Japan, ~ Stanford University School of Medicine, Stanford, California, and + Palo Alto Medical Clinic, Palo Alto, California n colorectal cancer the Dukes staging system 1' 2 From 1970 to 1985, 663 patients underwent curative resection of colon and rectal adenocarcinomas. All sur- I has been the most widely employed classifica- gical specimens were examined for tumor "budding," tion scheme since it is simple to apply and provides defined as small clusters of undifferentiated cancer cells useful prognostic information. However, it is well ahead of the invasive front of the lesion. Patients were divided into two groups according to degree of budding: known that some patients with cancer of the colon none or mild (BD-1) and moderate or severe (BD-2). BD- or rectum have more rapidly progressive disease, 1 occurred in 493 patients (74.4 percent), and BD-2 was compared with other patients in the same Dukes found in 170 patients (25.6 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Diseases of the Colon & Rectum Wolters Kluwer Health

Prognostic value of tumor “budding” in patients with colorectal cancer

Vierra, Mark
Diseases of the Colon & Rectum , Volume 36 (7) – Jul 1, 1993
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References (23)

Copyright
© 1993 American Society of Colon and Rectal Surgeons
ISSN
0012-3706
eISSN
1530-0358
DOI
10.1007/BF02238588
Publisher site
See Article on Publisher Site

Abstract

Diseases of the Volume Number 36 Comx REcrvM 7 JULY 1993 ORIGINAL CONTRIBUTIONS Prognostic Value of Tumor "Budding" in Patients with Colorectal Cancer Kazuo Hase, M.D.,* Clayton Shatney, M.D.,J- Denise Johnson, M.D.,J- Michael Trollope, M.D.,:~ Mark Vierra, M.D.-~ From the Departments of Surgery, *National Defense Medical College, Saitama, Japan, ~ Stanford University School of Medicine, Stanford, California, and + Palo Alto Medical Clinic, Palo Alto, California n colorectal cancer the Dukes staging system 1' 2 From 1970 to 1985, 663 patients underwent curative resection of colon and rectal adenocarcinomas. All sur- I has been the most widely employed classifica- gical specimens were examined for tumor "budding," tion scheme since it is simple to apply and provides defined as small clusters of undifferentiated cancer cells useful prognostic information. However, it is well ahead of the invasive front of the lesion. Patients were divided into two groups according to degree of budding: known that some patients with cancer of the colon none or mild (BD-1) and moderate or severe (BD-2). BD- or rectum have more rapidly progressive disease, 1 occurred in 493 patients (74.4 percent), and BD-2 was compared with other patients in the same Dukes found in 170 patients (25.6

Journal

Diseases of the Colon & Rectum – Wolters Kluwer Health

Published: Jul 1, 1993

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