Abstract

Thorax 16, (1961), A COMPARISON OF PHYSIOLOGICAL AND PATHOLOGICAL FINDINGS IN CHRONIC BRONCHITIS AND EMPHYSEMA, WITH SPECIAL REFERENCE TO RESPONSE TO EXERCISE BY G. R. McNAB, W. S. GROVE, AND S. NARIMAN* From the Respiratory Physiology Laboratory, Foxhall Hospital, Ipswich FOR PUBLICATION JUNE 28, 1960) (RECEIVED EXERCISE.-The standard exercise was three minutes Any senior medical student is expected to pedalling on an exercycle with a set resistance. A recognize the picture of clinical emphysema, state is normally shown at this time by the steady many authors, such as Fletcher (1952), feel though simultaneous tracing of ventilation and oxygen that it is an unreliable diagnosis. Within the last uptake; Donald, Bishop, and Wade (1954) had found 30 years radiological emphysema has been 20 to this by other methods. to the syndrome (Simon and Galbraith, added the effect of exercise on We have investigated 1953), and in the last 15 years the emphasis has oxygen, and (b) ventilation equivalent for (a) arterial disorders of pulmonary on the associated been Since we think that the relationship of forced oxygen. factors as defects in forced physiology. Such ventilation tests to the stresses of real life is slight, we functional residual capacity, low that