Intraoperative Blood Transfusion Contributes to Decreased Long-Term Survival of Patients With Esophageal Cancer

World J Surg (2012) 36:844–850 DOI 10.1007/s00268-012-1433-3 Intraoperative Blood Transfusion Contributes to Decreased Long-Term Survival of Patients With Esophageal Cancer • • Yoshihiro Komatsu Hajime Orita • • Mutsumi Sakurada Hiroshi Maekawa Toshitaka Hoppo Koichi Sato Published online: 17 February 2012 Socie ´te ´ Internationale de Chirurgie 2012 Abstract the presence of lymphatic and vascular invasion was Background Several prognostic factors for patients who comparable between the groups, but the Kaplan–Meier have undergone esophagectomy owing to esophageal survival analysis demonstrated that survival was signifi- squamous cell carcinoma have been suggested, including cantly worse in the BG group than in the LBG group intraoperative blood loss. There are few data, however, (p = 0.00295). This was supported by the multivariate suggesting such an association with the prognosis follow- analysis, which indicated that intraoperative blood loss was ing radical esophagectomy. independently associated with long-term survival after Methods Patients with esophageal squamous cell carci- radical esophagectomy. noma who underwent radical esophagectomy were divided Conclusions Intraoperative blood loss could be a useful into two groups based on the median value of the intra- prognostic factor following radical esophagectomy in operative blood loss (510 g). A multivariate Cox propor- patients with esophageal squamous cell carcinoma. tional-hazard regression analysis was performed to determine if intraoperative blood loss could be an inde- Introduction pendent prognostic factor for long-term survival following radical esophagectomy. Kaplan–Meier survival analysis Worldwide, esophageal cancer has been a significantly with a log-rank test was performed between the groups. Results From April 2005 to May 2009, a total of 37 increasing health problem, being the seventh leading cause of cancer-related death. In 2005,...