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Case-Control Studies: Design, Conduct, Analysis
- Publisher
- Wiley
- Copyright
- Copyright © 1999 Wiley Subscription Services
- ISSN
- 0041-1132
- eISSN
- 1537-2995
- DOI
- 10.1046/j.1537-2995.1999.39070701.x
- Publisher site
- See Article on Publisher Site
Abstract
BACKGROUND: Various bioactive substances are released from white cell (WBC) granules into red cell (RBC) components in a time‐dependent manner during blood storage. Some of these substances may have immunosuppressive effects and may contribute to transfusion‐induced immunomodulation. RBCs transfused after prolonged storage may be associated with a higher incidence of postoperative infections than fresh RBCs. This hypothesis does not seem to have been investigated in a clinical study.
Journal
Transfusion – Wiley
Published: Jan 1, 1999
Keywords: ; ; ; ;