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References (37)
-
S. Sawa, M. Cherrier, M. Lochner, Naoko Satoh‐Takayama, H. Fehling, Francina Langa, J. Santo, G. Eberl (2010)
Lineage Relationship Analysis of RORγt+ Innate Lymphoid CellsScience, 330
-
J. Bollrath, T. Phesse, Vivian Burstin, T. Putoczki, Moritz Bennecke, Trudie Bateman, Tim Nebelsiek, Therese Lundgren-May, Ozge Canli, S. Schwitalla, V. Matthews, R. Schmid, T. Kirchner, M. Arkan, M. Ernst, F. Greten (2009)
gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis.Cancer cell, 15 2
-
B. Koning, J. Dieren, D. Lindenbergh‐Kortleve, M. Sluis, Tetsuya Matsumoto, K. Yamaguchi, A. Einerhand, J. Samsom, R. Pieters, E. Nieuwenhuis (2006)
Contributions of mucosal immune cells to methotrexate-induced mucositis.International immunology, 18 6
-
L. Vereecke, R. Beyaert, G. Loo (2011)
Enterocyte death and intestinal barrier maintenance in homeostasis and disease.Trends in molecular medicine, 17 10
-
S. Grivennikov, E. Karin, J. Terzic, D. Mucida, Guann-Yi Yu, S. Vallabhapurapu, J. Scheller, S. Rose-John, H. Cheroutre, L. Eckmann, M. Karin (2009)
IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer.Cancer cell, 15 2
-
Risto Renkonen (1987)
Immunobiology of acute graft-versus-host disease.Medical biology, 65 5-6
-
M. Verburg, I. Renes, D. Nispen, S. Ferdinandusse, M. Jorritsma, H. Büller, A. Einerhand, J. Dekker (2002)
Specific Responses in Rat Small Intestinal Epithelial mRNA Expression and Protein Levels During Chemotherapeutic Damage and RegenerationJournal of Histochemistry & Cytochemistry, 50
-
S. Sonis (2004)
The pathobiology of mucositisNature Reviews Cancer, 4
-
L. Peterson, D. Artis (2014)
Intestinal epithelial cells: regulators of barrier function and immune homeostasisNature Reviews Immunology, 14
-
M. Frank, Eva Hennenberg, Annette Eyking, M. Rünzi, G. Gerken, P. Scott, J. Parkhill, A. Walker, E. Cario (2015)
TLR Signaling Modulates Side Effects of Anticancer Therapy in the Small IntestineThe Journal of Immunology, 194
-
M. Visentin, R. Zhao, I. Goldman (2012)
The antifolates.Hematology/oncology clinics of North America, 26 3
-
H. Miyoshi, R. Ajima, C. Luo, T. Yamaguchi, T. Stappenbeck (2012)
Wnt5a Potentiates TGF-β Signaling to Promote Colonic Crypt Regeneration After Tissue InjuryScience, 338
-
M. Ernst, S. Thiem, Paul Nguyen, M. Eissmann, T. Putoczki (2014)
Epithelial gp130/Stat3 functions: an intestinal signaling node in health and disease.Seminars in immunology, 26 1
-
C. Anderson, G. Boucher, Charlie Lees, A. Franke, Mauro D’Amato, K. Taylor, James Lee, P. Goyette, M. Imieliński, A. Latiano, Caroline Lagacé, R. Scott, L. Amininejad, S. Bumpstead, L. Baidoo, R. Baldassano, M. Barclay, Theodore Bayless, S. Brand, C. Büning, J. Colombel, L. Denson, M. Vos, Marla Dubinsky, C. Edwards, D. Ellinghaus, R. Fehrmann, J. Floyd, T. Florin, D. Franchimont, L. Franke, Michel Georges, J. Glas, N. Glazer, S. Guthery, T. Haritunians, N. Hayward, J. Hugot, Gilles Jobin, D. Laukens, I. Lawrance, M. Lémann, Arie Levine, C. Libioulle, É. Louis, D. McGovern, M. Milla, G. Montgomery, K. Morley, C. Mowat, Aylwin Ng, W. Newman, Roel Ophoff, L. Papi, O. Palmieri, L. Peyrin-Biroulet, J. Panés, A. Phillips, N. Prescott, D. Proctor, R. Roberts, Richard Russell, P. Rutgeerts, J. Sanderson, M. Sans, P. Schumm, F. Seibold, Y. Sharma, L. Simms, Mark Seielstad, A. Steinhart, S. Targan, Leonard Berg, Morten Vatn, H. Verspaget, T. Walters, C. Wijmenga, D. Wilson, H. Westra, R. Xavier, Z. Zhao, C. Ponsioen, V. Andersen, L. Torkvist, M. Gazouli, N. Anagnou, T. Karlsen, L. Kupčinskas, Jurgita Šventoraitytė, John Mansfield, S. Kugathasan, M. Silverberg, J. Halfvarson, Jerome Rotter, Christopher Mathew, A. Griffiths, R. Gearry, Tariq Ahmad, S. Brant, M. Chamaillard, J. Satsangi, Judy Cho, S. Schreiber, Mark Daly, J. Barrett, M. Parkes, V. Annese, H. Hakonarson, G. Radford-Smith, R. Duerr, S. Vermeire, R. Weersma, J. Rioux (2011)
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47Nature genetics, 43
-
H. Spits, T. Cupedo (2012)
Innate lymphoid cells: emerging insights in development, lineage relationships, and function.Annual review of immunology, 30
-
James Matthews, Owen Sansom, A. Clarke (2011)
Absolute requirement for STAT3 function in small-intestine crypt stem cell survivalCell Death and Differentiation, 18
-
Toshiro Sato, R. Vries, H. Snippert, M. Wetering, N. Barker, D. Stange, J. Es, A. Abo, P. Kujala, P. Peters, H. Clevers (2009)
Single Lgr5 stem cells build cryptvillus structures in vitro without a mesenchymal nicheNature, 459
-
P. Reddy, J. Ferrara (2003)
Immunobiology of acute graft-versus-host disease.Blood reviews, 17 4
-
Potten (1978)
Differential radiation response amongst proliferating epithelial cellsCell Tissue Kinet., 11
-
Marco Demaria, Marco Demaria, Sandra Misale, C. Giorgi, Valentina Miano, A. Camporeale, Judy Campisi, Paolo Pinton, Valeria Poli (2012)
STAT3 can serve as a hit in the process of malignant transformation of primary cellsCell Death and Differentiation, 19
-
A. Heneghan, J. Pierre, K. Kudsk (2013)
JAK-STAT and intestinal mucosal immunologyJAK-STAT, 2
-
Bio X Cell) was administered i.p. to Lgr5-eGFP mice every 2 d, starting 5 d before the first MTX dose, until day 2 after the last MTX dose. Rag1 / mice were treated with 1 mg anti-IFN -
Naoko Satoh‐Takayama, Nicolas Serafini, T. Verrier, A. Rekiki, J. Renauld, G. Frankel, J. Santo (2014)
The chemokine receptor CXCR6 controls the functional topography of interleukin-22 producing intestinal innate lymphoid cells.Immunity, 41 5
-
Br ief Definitive Repor -
Christoph Klose, E. Kiss, V. Schwierzeck, Karolina Ebert, T. Hoyler, Y. d’Hargues, Nathalie Göppert, Andrew Croxford, A. Waisman, Y. Tanriver, A. Diefenbach (2013)
A T-bet gradient controls the fate and function of CCR6−RORγt+ innate lymphoid cellsNature, 494
-
G. Pickert, C. Neufert, M. Leppkes, Yan Zheng, Nadine Wittkopf, Moritz Warntjen, H. Lehr, S. Hirth, B. Weigmann, S. Wirtz, W. Ouyang, M. Neurath, C. Becker (2009)
STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healingThe Journal of Experimental Medicine, 206
-
ByYutaka Kanamori, Kaori Ishimaru, Koichi Ikuta, Hideo Nariuchi, Hiromichi Ishikawa (1996)
Identification of novel lymphoid tissues in murine intestinal mucosa where clusters of c-kit+ IL-7R+ Thy1+ lympho-hemopoietic progenitors developThe Journal of Experimental Medicine, 184
-
D. Artis, H. Spits (2015)
The biology of innate lymphoid cellsNature, 517
-
L. Ritsma, S. Ellenbroek, A. Zomer, H. Snippert, F. Sauvage, B. Simons, H. Clevers, J. Rheenen (2014)
Intestinal crypt homeostasis revealed at single stem cell level by in vivo live-imagingNature, 507
-
Christopher Potten (1990)
A comprehensive study of the radiobiological response of the murine (BDF1) small intestine.International journal of radiation biology, 58 6
-
C. Potten, S. Al-Barwari, J. Searle (1978)
Differential Radiation Response Amongst Proliferating Epithelial CellsCell Proliferation, 11
-
R. Gazit, Raizy Gruda, Moran Elboim, T. Arnon, Gil Katz, H. Achdout, J. Hanna, U. Qimron, Guy Landau, E. Greenbaum, Z. Zakay‐Rones, A. Porgador, O. Mandelboim (2006)
Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1Nature Immunology, 7
-
S. Salim, J. Söderholm (2011)
Importance of disrupted intestinal barrier in inflammatory bowel diseasesInflammatory Bowel Diseases, 17
-
C. Günther, H. Neumann, M. Neurath, C. Becker (2012)
Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epitheliumGut, 62
-
Ana Reynders, Nadia Yessaad, Thien-Phong Manh, M. Dalod, A. Fenis, Camille Aubry, Georgios Nikitas, Bertrand Escalière, J. Renauld, O. Dussurget, P. Cossart, Marc Lecuit, É. Vivier, E. Tomasello (2011)
Identity, regulation and in vivo function of gut NKp46+RORγt+ and NKp46+RORγt− lymphoid cellsThe EMBO Journal, 30
-
A. Hanash, J. Dudakov, Guoqiang Hua, Margaret O’Connor, L. Young, Natalie Singer, Mallory West, R. Jenq, A. Holland, Lucy Kappel, Arnab Ghosh, J. Tsai, U. Rao, N. Yim, Odette Smith, E. Velardi, E. Hawryluk, G. Murphy, Chen Liu, L. Fouser, R. Kolesnick, B. Blazar, M. Brink (2012)
Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease.Immunity, 37 2
-
T. Kawai, S. Akira (2006)
TLR signaling.Current topics in microbiology and immunology, 311
- Publisher
- Pubmed Central
- Copyright
- © 2015 Aparicio-Domingo et al.
- ISSN
- 0022-1007
- eISSN
- 1540-9538
- DOI
- 10.1084/jem.20150318
- Publisher site
- See Article on Publisher Site
Abstract
Type 3 lymphoid cells (ILC3s) are required for epithelial activation and proliferation in response to small intestinal tissue damage induced by chemotherapeutics. Multiple ILC3 subsets are activated after intestinal damage, and the absence of ILC3s or their signature cytokine IL-22 results in severely impaired maintenance of intestinal stem cells.
Journal
The Journal of Experimental Medicine – Pubmed Central
Published: Oct 19, 2015