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Mechanical Strength and Rheological Properties of Tissue Adhesives With Regard to Colorectal Anastomosis An Ex Vivo Study

Mechanical Strength and Rheological Properties of Tissue Adhesives With Regard to Colorectal... ORIGINAL ARTICLE Mechanical Strength and Rheological Properties of Tissue Adhesives With Regard to Colorectal Anastomosis An Ex Vivo Study ∗ ∗ ∗ Konstantinos Aristotelis Vakalopoulos, MSc, Zhouqiao Wu, MD, Leonard Kroese, MSc, Gert-Jan Kleinrensink, MD, PhD,† Johannes Jeekel, MD, PhD,† Richard Vendamme, PhD,‡ Dimitra Dodou, PhD,§ and Johan Frederik Lange, MD, PhD anastomotic leakage (AL) rates, which are known to be high in this Objective: To compare mechanical strength and rheology of existing tis- field. These experiments, mostly on animal models, provide insight sue adhesives in a clinically relevant test setup with regard to colorectal into the effectiveness of tissue adhesives on surgical complication anastomosis. rates, particularly AL. Background: Little is known on the mechanical strength of tissue adhesives Tissue adhesives work by forming a mechanical seal around an directly after application. Furthermore, rheological profiling may be important anastomosis, thus protecting it from leakage of intraluminal contents in understanding mechanical performance and explaining differences between and ameliorating effects of AL. Before curing, all adhesives are low- adhesives. This study provides new data on the mechanical strength and rhe- viscosity liquids that can efficiently flow into the pores of, in this case, ology of a comprehensive list of tissue adhesives http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Surgery Wolters Kluwer Health

Mechanical Strength and Rheological Properties of Tissue Adhesives With Regard to Colorectal Anastomosis An Ex Vivo Study

Lange, Johan Frederik
Annals of Surgery , Volume 261 (2) – Feb 1, 2015
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References (24)

Copyright
© 2014 Wolters Kluwer Health, Inc. All rights reserved.
ISSN
0003-4932
eISSN
1528-1140
DOI
10.1097/SLA.0000000000000599
pmid
24670843
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL ARTICLE Mechanical Strength and Rheological Properties of Tissue Adhesives With Regard to Colorectal Anastomosis An Ex Vivo Study ∗ ∗ ∗ Konstantinos Aristotelis Vakalopoulos, MSc, Zhouqiao Wu, MD, Leonard Kroese, MSc, Gert-Jan Kleinrensink, MD, PhD,† Johannes Jeekel, MD, PhD,† Richard Vendamme, PhD,‡ Dimitra Dodou, PhD,§ and Johan Frederik Lange, MD, PhD anastomotic leakage (AL) rates, which are known to be high in this Objective: To compare mechanical strength and rheology of existing tis- field. These experiments, mostly on animal models, provide insight sue adhesives in a clinically relevant test setup with regard to colorectal into the effectiveness of tissue adhesives on surgical complication anastomosis. rates, particularly AL. Background: Little is known on the mechanical strength of tissue adhesives Tissue adhesives work by forming a mechanical seal around an directly after application. Furthermore, rheological profiling may be important anastomosis, thus protecting it from leakage of intraluminal contents in understanding mechanical performance and explaining differences between and ameliorating effects of AL. Before curing, all adhesives are low- adhesives. This study provides new data on the mechanical strength and rhe- viscosity liquids that can efficiently flow into the pores of, in this case, ology of a comprehensive list of tissue adhesives

Journal

Annals of Surgery – Wolters Kluwer Health

Published: Feb 1, 2015

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