Access the full text.
Sign up today, get DeepDyve free for 14 days.
J. Massagué (2000)
How cells read TGF-beta signals.Nature reviews. Molecular cell biology, 1 3
R. Nagarajan, Jingming Zhang, Wei Li, Yan Chen (1999)
Regulation of Smad7 Promoter by Direct Association with Smad3 and Smad4*The Journal of Biological Chemistry, 274
S. Dennler, S. Huet, J. Gauthier (1999)
A short amino-acid sequence in MH1 domain is responsible for functional differences between Smad2 and Smad3Oncogene, 18
M. Kawabata, H. Inoue, A. Hanyu, T. Imamura, K. Miyazono (1998)
Smad proteins exist as monomers in vivo and undergo homo‐ and hetero‐oligomerization upon activation by serine/threonine kinase receptorsThe EMBO Journal, 17
K. Lehmann, E. Janda, C. Pierreux, M. Rytömaa, A. Schulze, M. McMahon, C. Hill, H. Beug, J. Downward (2000)
Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells.Genes & development, 14 20
M. Caestecker, W. Parks, Chistopher Frank, P. Castagnino, D. Bottaro, A. Roberts, R. Lechleider (1998)
Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases.Genes & development, 12 11
A. Moustakas, S. Souchelnytskyi, C. Heldin (2001)
Smad regulation in TGF-beta signal transduction.Journal of cell science, 114 Pt 24
J. Zavadil, M. Bitzer, D. Liang, Yuh Yang, A. Massimi, S. Kneitz, E. Piek, E. Bottinger (2001)
Genetic programs of epithelial cell plasticity directed by transforming growth factor-βProceedings of the National Academy of Sciences of the United States of America, 98
E. Janda, K. Lehmann, I. Killisch, M. Jechlinger, M. Herzig, J. Downward, H. Beug, S. Grünert (2002)
Ras and TGFβ cooperatively regulate epithelial cell plasticity and metastasisThe Journal of Cell Biology, 156
Xuedong Liu, Yin Sun, R. Weinberg, H. Lodish (2001)
Ski/Sno and TGF-β signalingCytokine & Growth Factor Reviews, 12
K. Yagi, D. Goto, Toshiaki Hamamoto, Seiichi Takenoshita, Mitsuyasu Kato, K. Miyazono (1999)
Alternatively Spliced Variant of Smad2 Lacking Exon 3The Journal of Biological Chemistry, 274
Ying Zhang, Xin-Hua Feng, R. Derynck (1998)
Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcriptionNature, 394
A. Roberts (2002)
The ever-increasing complexity of TGF-β signalingCytokine & Growth Factor Reviews, 13
S. Dennler, S. Itoh, D. Vivien, P. Dijke, S. Huet, J. Gauthier (1998)
Direct binding of Smad3 and Smad4 to critical TGFβ‐inducible elements in the promoter of human plasminogen activator inhibitor‐type 1 geneThe EMBO Journal, 17
(2001)
Access the most recent version at doi: 10.1101/gr.180801 References
P. Tamayo, D. Slonim, J. Mesirov, Q. Zhu, S. Kitareewan, E. Dmitrovsky, E. Lander, T. Golub (1999)
Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation.Proceedings of the National Academy of Sciences of the United States of America, 96 6
G. Gersdorff, K. Suszták, F. Rezvani, M. Bitzer, D. Liang, E. Böttinger (2000)
Smad3 and Smad4 Mediate Transcriptional Activation of the Human Smad7 Promoter by Transforming Growth Factor β*The Journal of Biological Chemistry, 275
Laurie Heyer, S. Kruglyak, Shibu Yooseph (1999)
Exploring expression data: identification and analysis of coexpressed genes.Genome research, 9 11
L. Jonk, S. Itoh, C. Heldin, P. Dijke, W. Kruijer (1998)
Identification and Functional Characterization of a Smad Binding Element (SBE) in the JunB Promoter That Acts as a Transforming Growth Factor-β, Activin, and Bone Morphogenetic Protein-inducible Enhancer*The Journal of Biological Chemistry, 273
G. Brodin, Aive Åhgren, P. Dijke, C. Heldin, R. Heuchel (2000)
Efficient TGF-β Induction of the Smad7 Gene Requires Cooperation between AP-1, Sp1, and Smad Proteins on the Mouse Smad7 Promoter*The Journal of Biological Chemistry, 275
R. Chambers, P. Leoni, N. Kaminski, G. Laurent, R. Heller (2003)
Global expression profiling of fibroblast responses to transforming growth factor-beta1 reveals the induction of inhibitor of differentiation-1 and provides evidence of smooth muscle cell phenotypic switching.The American journal of pathology, 162 2
E. Piek, A. Moustakas, A. Kurisaki, C. Heldin, P. Dijke (1999)
TGF-(beta) type I receptor/ALK-5 and Smad proteins mediate epithelial to mesenchymal transdifferentiation in NMuMG breast epithelial cells.Journal of cell science, 112 ( Pt 24)
D. Wotton, R. Lo, L. Swaby, J. Massagué (1999)
Multiple Modes of Repression by the Smad Transcriptional Corepressor TGIF*The Journal of Biological Chemistry, 274
J. Massagué (2000)
How cells read TGF-β signalsNature Reviews Molecular Cell Biology, 1
K. Quandt, K. Frech, H. Karas, E. Wingender, Thomas Werner (1995)
MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data.Nucleic acids research, 23 23
E. Piek, W. Ju, J. Heyer, D. Escalante-Alcalde, C. Stewart, M. Weinstein, C. Deng, R. Kucherlapati, E. Böttinger, A. Roberts (2001)
Functional Characterization of Transforming Growth Factor β Signaling in Smad2- and Smad3-deficient Fibroblasts*The Journal of Biological Chemistry, 276
M. Kretzschmar, J. Doody, I. Timokhina, J. Massagué (1999)
A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras.Genes & development, 13 7
R. Derynck, R. Akhurst, A. Balmain (2001)
TGF-β signaling in tumor suppression and cancer progressionNature Genetics, 29
E. Wingender, Xin Chen, R. Hehl, H. Karas, I. Liebich, V. Matys, T. Meinhardt, M. Prüß, I. Reuter, F. Schacherer (2000)
TRANSFAC: an integrated system for gene expression regulationNucleic acids research, 28 1
Proceedings of the National Academy of Sciences – Unpaywall
Published: Aug 20, 2003
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.