Autophagic receptor p62 protects against glycation‐derived toxicity and enhances viability

Gemma Aragonès; Kalavathi Dasuri; Opeoluwa Olukorede; Sarah G. Francisco; Carol Renneburg; Caroline Kumsta; Malene Hansen; Shun Kageyama; Masaaki Komatsu; Sheldon Rowan; Jonathan Volkin; Michael Workman; Wenxin Yang; Paula Daza; Diego Ruano; Helena Dominguez‐Martín; José Antonio Rodríguez‐Navarro; Xue‐Liang Du; Michael A. Brownlee; Eloy Bejarano; Allen Taylor

doi:10.1111/acel.13257

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Ozcelik, S. , Fraser, G. , Castets, P. , Schaeffer, V. , Skachokova, Z. , Breu, K. , Clavaguera, F. , Sinnreich, M. , Kappos, L. , Goedert, M. , Tolnay, M. , & Winkler, D. T. (2013). Rapamycin attenuates the progression of tau pathology in P301S tau transgenic mice. PLoS One, 8(5), e62459 10.1371/journal.pone.0062459 23667480, Ozcelik, S. , Fraser, G. , Castets, P. , Schaeffer, V. , Skachokova, Z. , Breu, K. , Clavaguera, F. , Sinnreich, M. , Kappos, L. , Goedert, M. , Tolnay, M. , & Winkler, D. T. (2013). Rapamycin attenuates the progression of tau pathology in P301S tau transgenic mice. PLoS One, 8(5), e62459 10.1371/journal.pone.0062459 23667480
( Schlotterer, A. , Kukudov, G. , Bozorgmehr, F. , Hutter, H. , Du, X. , Oikonomou, D. , Ibrahim, Y. , Pfisterer, F. , Rabbani, N. , Thornalley, P. , Sayed, A. , Fleming, T. , Humpert, P. , Schwenger, V. , Zeier, M. , Hamann, A. , Stern, D. , Brownlee, M. , Bierhaus, A. , … Morcos, M. (2009). C. elegans as model for the study of high glucose‐ mediated life span reduction. Diabetes, 58(11), 2450‐2456. 10.2337/db09-0567 19675139)
Schlotterer, A. , Kukudov, G. , Bozorgmehr, F. , Hutter, H. , Du, X. , Oikonomou, D. , Ibrahim, Y. , Pfisterer, F. , Rabbani, N. , Thornalley, P. , Sayed, A. , Fleming, T. , Humpert, P. , Schwenger, V. , Zeier, M. , Hamann, A. , Stern, D. , Brownlee, M. , Bierhaus, A. , … Morcos, M. (2009). C. elegans as model for the study of high glucose‐ mediated life span reduction. Diabetes, 58(11), 2450‐2456. 10.2337/db09-0567 19675139
Schlotterer, A. , Kukudov, G. , Bozorgmehr, F. , Hutter, H. , Du, X. , Oikonomou, D. , Ibrahim, Y. , Pfisterer, F. , Rabbani, N. , Thornalley, P. , Sayed, A. , Fleming, T. , Humpert, P. , Schwenger, V. , Zeier, M. , Hamann, A. , Stern, D. , Brownlee, M. , Bierhaus, A. , … Morcos, M. (2009). C. elegans as model for the study of high glucose‐ mediated life span reduction. Diabetes, 58(11), 2450‐2456. 10.2337/db09-0567 19675139, Schlotterer, A. , Kukudov, G. , Bozorgmehr, F. , Hutter, H. , Du, X. , Oikonomou, D. , Ibrahim, Y. , Pfisterer, F. , Rabbani, N. , Thornalley, P. , Sayed, A. , Fleming, T. , Humpert, P. , Schwenger, V. , Zeier, M. , Hamann, A. , Stern, D. , Brownlee, M. , Bierhaus, A. , … Morcos, M. (2009). C. elegans as model for the study of high glucose‐ mediated life span reduction. Diabetes, 58(11), 2450‐2456. 10.2337/db09-0567 19675139
( Uchiki, T. , Weikel, K. A. , Jiao, W. , Shang, F. U. , Caceres, A. , Pawlak, D. , Handa, J. T. , Brownlee, M. , Nagaraj, R. , & Taylor, A. (2012). Glycation‐altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age‐related disease (in nondiabetics). Aging Cell, 11(1), 1‐13. 10.1111/j.1474-9726.2011.00752.x 21967227)
Uchiki, T. , Weikel, K. A. , Jiao, W. , Shang, F. U. , Caceres, A. , Pawlak, D. , Handa, J. T. , Brownlee, M. , Nagaraj, R. , & Taylor, A. (2012). Glycation‐altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age‐related disease (in nondiabetics). Aging Cell, 11(1), 1‐13. 10.1111/j.1474-9726.2011.00752.x 21967227
Uchiki, T. , Weikel, K. A. , Jiao, W. , Shang, F. U. , Caceres, A. , Pawlak, D. , Handa, J. T. , Brownlee, M. , Nagaraj, R. , & Taylor, A. (2012). Glycation‐altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age‐related disease (in nondiabetics). Aging Cell, 11(1), 1‐13. 10.1111/j.1474-9726.2011.00752.x 21967227, Uchiki, T. , Weikel, K. A. , Jiao, W. , Shang, F. U. , Caceres, A. , Pawlak, D. , Handa, J. T. , Brownlee, M. , Nagaraj, R. , & Taylor, A. (2012). Glycation‐altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age‐related disease (in nondiabetics). Aging Cell, 11(1), 1‐13. 10.1111/j.1474-9726.2011.00752.x 21967227

Publisher: Wiley
eISSN: 1474-9726
DOI: 10.1111/acel.13257
Publisher site: See Article on Publisher Site

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Autophagic receptor p62 protects against glycation‐derived toxicity and enhances viability

Autophagic receptor p62 protects against glycation‐derived toxicity and enhances viability

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Autophagic receptor p62 protects against glycation‐derived toxicity and enhances viability

Autophagic receptor p62 protects against glycation‐derived toxicity and enhances viability

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