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- Publisher
- Springer Journals
- Copyright
- Copyright
- Subject
- Medicine & Public Health; Gynecology; Reproductive Medicine; Human Genetics
- ISSN
- 1058-0468
- eISSN
- 1573-7330
- DOI
- 10.1007/BF01203815
- Publisher site
- See Article on Publisher Site
Abstract
The present study was carried out from in vitro fertilization (IVF) attempts to analyze further the total and specific protein contents of 47 follicular fluids yielding one oocyte. The aim was to find correlations between the follicular concentrations of such proteins and the occurrence of coupled oocyte cleavage. These findings would be used as markers of IVF outcome. Two groups of follicular samples were distinguished: one group with cleavage occurrence (25 cases) and another group without cleavage or even fertilization (22 cases). In the group with cleavage a significantly higher level was observed for six proteins: C3 complement fraction and ceruleoplasmin (P <0.02), α-antitrypsin and transferrin (P <0.01), and α2-macroglobulin and β2-microglobulin (P <0.001). The data are discussed with respect to changes in follicle permeability with advancing maturity.
Journal
Journal of Assisted Reproduction and Genetics – Springer Journals
Published: Feb 5, 2005