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Angiogenesis ProtocolsRat Aortic Ring

Angiogenesis Protocols: Rat Aortic Ring [Angiogenesis is a necessary component of normal tissue repair, tumor growth and dissemination, and a wide variety of other inflammatory and pathological processes as well, including diabetic retinopathy, rheumatoid arthritis, and psoriasis. Consequently, the last two decades have seen extensive research into the regulation of neovascularization, particularly in tumors. Partly due to the emphasis on tumor angiogenesis, much of this effort has been devoted to the detection and characterization of angiogenic growth factors and inhibitory molecules. Thus assays have commonly been developed to measure the amount of vascular growth in vivo, or the modulation of endothelial cell (EC) proliferation, or migration in simple 2D culture systems (1).] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

Angiogenesis ProtocolsRat Aortic Ring

Part of the Methods in Molecular Medicine™ Book Series (volume 46)
Editors: Murray, J. Clifford
Burbridge, Mike F.; West, David C.
Angiogenesis Protocols — Jan 1, 2001
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19 pages

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References (18)

Publisher
Humana Press
Copyright
© Humana Press 2001
ISBN
978-0-89603-698-7
Pages
185–204
DOI
10.1385/1-59259-143-4:185
Publisher site
See Chapter on Publisher Site

Abstract

[Angiogenesis is a necessary component of normal tissue repair, tumor growth and dissemination, and a wide variety of other inflammatory and pathological processes as well, including diabetic retinopathy, rheumatoid arthritis, and psoriasis. Consequently, the last two decades have seen extensive research into the regulation of neovascularization, particularly in tumors. Partly due to the emphasis on tumor angiogenesis, much of this effort has been devoted to the detection and characterization of angiogenic growth factors and inhibitory molecules. Thus assays have commonly been developed to measure the amount of vascular growth in vivo, or the modulation of endothelial cell (EC) proliferation, or migration in simple 2D culture systems (1).]

Published: Jan 1, 2001

Keywords: Diabetic Retinopathy; Aortic Ring; Angiogenic Response; Endogenous Growth Factor; Clean Petri Dish

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