Access the full text.
Sign up today, get DeepDyve free for 14 days.
Brian Haas, Kazufumi Omura, R. Constable, T. Canli (2007)
Emotional conflict and neuroticism: personality-dependent activation in the amygdala and subgenual anterior cingulate.Behavioral neuroscience, 121 2
Ying Li, Jin-Ju Li, Long-chuan Yu (2002)
Anti-nociceptive effect of neuropeptide Y in the nucleus accumbens of rats: an involvement of opioid receptors in the effectBrain Research, 940
A. Hariri, V. Mattay, A. Tessitore, B. Kolachana, F. Fera, D. Goldman, M. Egan, D. Weinberger (2002)
Serotonin Transporter Genetic Variation and the Response of the Human AmygdalaScience, 297
Thomas Adrian, J. Allen, S. Bloom, M. Ghatei, M. Rossor, Gareth Roberts, T. Crow, K. Tatemoto, J. Polak (1983)
Neuropeptide Y distribution in human brainNature, 306
K. Britton, S. Southerland (2001)
Naloxone blocks ‘anxiolytic’ effects of neuropeptide YPeptides, 22
B. McEwen (1999)
Stress and hippocampal plasticity.Annual review of neuroscience, 22
K. Tatemoto, M. Carlquist, V. Mutt (1982)
Neuropeptide Y—a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptideNature, 296
R. Allen, J. Boublik, R. Hauger, N. Scott, J. Rivier, Marvin Brown (1991)
NEUROPEPTIDE Y RADIO‐IMMUNOASSAY: CHARACTERIZATION AND APPLICATIONClinical and Experimental Pharmacology and Physiology, 18
M. Enoch, Pei-Hong Shen, Ke Xu, C. Hodgkinson, D. Goldman (2006)
Using ancestry-informative markers to define populations and detect population stratificationJournal of Psychopharmacology, 20
L. Niskanen, R. Voutilainen-Kaunisto, M. Teräsvirta, M. Karvonen, R. Valve, U. Pesonen, M. Laakso, M. Uusitupa, M. Koulu (2000)
Leucine 7 to proline 7 polymorphism in the neuropeptide y gene is associated with retinopathy in type 2 diabetes.Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 108 3
A. Thorsell, Katrina Carlsson, Rolf Ekman, Markus Heilig (1999)
Behavioral and endocrine adaptation, and up-regulation of NPY expression in rat amygdala following repeated restraint stress.Neuroreport, 10 14
B. McEwen, E. Stellar (1993)
Stress and the individual. Mechanisms leading to disease.Archives of internal medicine, 153 18
N. Rosenberg, Lei Li, R. Ward, J. Pritchard (2003)
Informativeness of genetic markers for inference of ancestry.American journal of human genetics, 73 6
R. Sinha, Miguel García, P. Paliwal, M. Kreek, B. Rounsaville (2006)
Stress-induced cocaine craving and hypothalamic-pituitary-adrenal responses are predictive of cocaine relapse outcomes.Archives of general psychiatry, 63 3
J. Barrett, B. Fry, J. Maller, M. Daly (2005)
Haploview: analysis and visualization of LD and haplotype mapsBioinformatics, 21 2
S. Sen, M. Burmeister, D. Ghosh (2004)
Meta‐analysis of the association between a serotonin transporter promoter polymorphism (5‐HTTLPR) and anxiety‐related personality traitsAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 127B
A. Caspi, J. McClay, T. Moffitt, J. Mill, Judy Martin, I. Craig, Alan Taylor, R. Poulton (2002)
Role of Genotype in the Cycle of Violence in Maltreated ChildrenScience, 297
M. Karvonen, U. Pesonen, M. Koulu, L. Niskanen, M. Laakso, A. Rissanen, J. Dekker, L. Hart, R. Valve, M. Uusitupa (1998)
Association of a leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y with high serum cholesterol and LDL cholesterol levelsNature Medicine, 4
A. Tessitore, A. Hariri, F. Fera, W. Smith, T. Chase, T. Hyde, D. Weinberger, V. Mattay (2002)
Dopamine Modulates the Response of the Human Amygdala: A Study in Parkinson's DiseaseThe Journal of Neuroscience, 22
J. Zubieta, Y. Smith, J. Bueller, Yanjun Xu, M. Kilbourn, D. Jewett, Charles Meyer, R. Koeppe, C. Stohler (2001)
Regional Mu Opioid Receptor Regulation of Sensory and Affective Dimensions of PainScience, 293
B. McEwen (2000)
Allostasis and Allostatic Load: Implications for NeuropsychopharmacologyNeuropsychopharmacology, 22
L. Pezawas, A. Meyer-Lindenberg, E. Drabant, B. Verchinski, K. Muñoz, B. Kolachana, M. Egan, V. Mattay, A. Hariri, D. Weinberger (2005)
5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depressionNature Neuroscience, 8
Alan Templeton, K. Crandall, C. Sing (1992)
A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping and DNA sequence data. III. Cladogram estimation.Genetics, 132 2
Guanshan Zhu, Robert Lipsky, Ke Xu, Sameer Ali, T. Hyde, J. Kleinman, Longina Akhtar, D. Mash, D. Goldman (2004)
Differential expression of human COMT alleles in brain and lymphoblasts detected by RT-coupled 5′ nuclease assayPsychopharmacology, 177
L. Watkins, D. Mayer (1982)
Organization of endogenous opiate and nonopiate pain control systems.Science, 216 4551
M. Stephens, P. Donnelly (2003)
A comparison of bayesian methods for haplotype reconstruction from population genotype data.American journal of human genetics, 73 5
A. Caspi, K. Sugden, T. Moffitt, Alan Taylor, I. Craig, H. Harrington, J. McClay, J. Mill, Judith Martin, A. Braithwaite, R. Poulton (2003)
Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT GeneScience, 301
L. Somerville, Hackjin Kim, T. Johnstone, A. Alexander, P. Whalen (2004)
Human amygdala responses during presentation of happy and neutral faces: correlations with state anxietyBiological Psychiatry, 55
M. Heilig, B. Söderpalm, J. Engel, E. Widerlöv (2004)
Centrally administered neuropeptide Y (NPY) produces anxiolytic-like effects in animal anxiety modelsPsychopharmacology, 98
J. Zubieta, M. Heitzeg, Y. Smith, J. Bueller, Ke Xu, Yanjun Xu, R. Koeppe, C. Stohler, D. Goldman (2003)
COMT val158met Genotype Affects µ-Opioid Neurotransmitter Responses to a Pain StressorScience, 299
Y. Allen, T. Adrian, J. Allen, K. Tatemoto, T. Crow, S. Bloom, J. Polak (1983)
Neuropeptide Y distribution in the rat brain.Science, 221 4613
A. Moles, B. Kieffer, F. D'Amato (2004)
Deficit in Attachment Behavior in Mice Lacking the µ-Opioid Receptor GeneScience, 304
Alan Templeton (1995)
A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping or DNA sequencing. V. Analysis of case/control sampling designs: Alzheimer's disease and the apoprotein E locus.Genetics, 140 1
A. Hariri, E. Drabant, K. Muñoz, B. Kolachana, V. Mattay, M. Egan, D. Weinberger (2005)
A susceptibility gene for affective disorders and the response of the human amygdala.Archives of general psychiatry, 62 2
A. Heinz, D. Braus, M. Smolka, J. Wrase, I. Puls, D. Hermann, Sabine Klein, S. Grüsser, H. Flor, G. Schumann, K. Mann, C. Büchel (2005)
Amygdala-prefrontal coupling depends on a genetic variation of the serotonin transporterNature Neuroscience, 8
P. Broqua, J. Wettstein, M. Rocher, B. Gauthier-Martin, J. Junien (1995)
Behavioral effects of neuropeptide Y receptor agonists in the elevated plus‐maze and fear‐potentiated startle proceduresBehavioural Pharmacology, 6
An individual's ability to deal with stress and anxiety — risk factors for many diseases — varies widely across human populations and the factors contributing to emotional resilience are complex. A study led by researchers at the National Institute on Alcohol Abuse and Alcoholism now points to inherited variations in the expression of the natural anxiolytic peptide neuropeptide Y in the brain as a factor in determining why some people can withstand stress better than others.
Nature – Springer Journals
Published: Apr 2, 2008
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.