Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 7-Day Trial for You or Your Team.

Learn More →

Diet Effects in Gut Microbiome and Obesity

Diet Effects in Gut Microbiome and Obesity The 100 trillion microbes in human gut coevolve with the host and exert significant influences on human health. The gut microbial composition presents dynamic changes correlated with various factors including host genotypes, age, and external environment. Effective manipulation of the gut microbiota through diets (both long‐term and short‐term diet patterns), probiotics and/or prebiotics, and antibiotics has been proved being potential to prevent from metabolic disorders such as obesity in many studies. The dietary regulation exerts influences on microbial metabolism and host immune functions through several pathways, of which may include selectively bacterial fermentation of nutrients, lower intestinal barrier function, overexpression of genes associated with disorders, and disruptions to both innate and adaptive immunity. Discoveries in the interrelationship between diet, intestinal microbiome, and body immune system provide us novel perceptions to the specific action mechanisms and will promote the development of therapeutic approaches for obesity. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Food Science Wiley

Diet Effects in Gut Microbiome and Obesity

Chen, Jia; He, Xianzhi; Huang, Jinhai
Journal of Food Science , Volume 79 (4) – Apr 1, 2014
Download PDF
10 pages

 
/lp/wiley/diet-effects-in-gut-microbiome-and-obesity-iZDo9tNMqb

References (153)

Publisher
Wiley
Copyright
"© 2014 Institute of Food Technologists®"
ISSN
0022-1147
eISSN
1750-3841
DOI
10.1111/1750-3841.12397
pmid
24621052
Publisher site
See Article on Publisher Site

Abstract

The 100 trillion microbes in human gut coevolve with the host and exert significant influences on human health. The gut microbial composition presents dynamic changes correlated with various factors including host genotypes, age, and external environment. Effective manipulation of the gut microbiota through diets (both long‐term and short‐term diet patterns), probiotics and/or prebiotics, and antibiotics has been proved being potential to prevent from metabolic disorders such as obesity in many studies. The dietary regulation exerts influences on microbial metabolism and host immune functions through several pathways, of which may include selectively bacterial fermentation of nutrients, lower intestinal barrier function, overexpression of genes associated with disorders, and disruptions to both innate and adaptive immunity. Discoveries in the interrelationship between diet, intestinal microbiome, and body immune system provide us novel perceptions to the specific action mechanisms and will promote the development of therapeutic approaches for obesity.

Journal

Journal of Food Science – Wiley

Published: Apr 1, 2014

Keywords: ; ; ;

There are no references for this article.