Li Wang, E. Seeley, W. Wickner, A. Merz (2002)
Vacuole Fusion at a Ring of Vertex Docking Sites Leaves Membrane Fragments within the OrganelleCell, 108
M. Bretou, C. Anne, F. Darchen (2008)
A Fast Mode of Membrane Fusion Dependent on Tight SNARE ZipperingThe Journal of Neuroscience, 28
N. Düzgüneş (2003)
Preparation and quantitation of small unilamellar liposomes and large unilamellar reverse-phase evaporation liposomes.Methods in enzymology, 367
T. Einert, Charles Sing, A. Alexander-Katz, Roland Department, Technische Muenchen, James-Franck-Strasse, Germany Science, Engineering, M. Technology, Cambridge, Ma, Ulrich Physik, Freie Berlin, Berlin, Germany (2011)
Conformational dynamics and internal friction in homopolymer globules: equilibrium vs. non-equilibrium simulationsThe European Physical Journal E, 34
J. Wong, D. Koppel, A. Cowan, G. Wessel (2007)
Membrane hemifusion is a stable intermediate of exocytosis.Developmental cell, 12 4
I. Cheddadi, P. Saramito, B. Dollet, C. Raufaste, François Graner (2011)
Understanding and predicting viscous, elastic, plastic flowsThe European Physical Journal E, 34
P. Kinnunen, J. Holopainen (2000)
Mechanisms of Initiation of Membrane Fusion: Role of LipidsBioscience Reports, 20
Jaideep Kesavan, M. Borisovska, D. Bruns (2007)
v-SNARE Actions during Ca2+-Triggered ExocytosisCell, 131
Although it was previously shown that a Noggin-soaked bead implanted into a somite partially disturbed SA progenitors, this might be due to an incomplete inhibition of BMPs
J. McNew, T. Weber, D. Engelman, T. Söllner, J. Rothman (1999)
The length of the flexible SNAREpin juxtamembrane region is a critical determinant of SNARE-dependent fusion.Molecular cell, 4 3
Yi Xu, A. Seven, L. Su, Q. Jiang, J. Rizo (2011)
Membrane Bridging and Hemifusion by Denaturated Munc18PLoS ONE, 6
D. Fasshauer, M. Margittai (2004)
A Transient N-terminal Interaction of SNAP-25 and Syntaxin Nucleates SNARE Assembly*Journal of Biological Chemistry, 279
O. López, M. Cocera, L. Coderch, J. Parra, and Barsukov, A. Maza (2001)
Octyl Glucoside-Mediated Solubilization and Reconstitution of Liposomes: Structural and Kinetic Aspects ‡Journal of Physical Chemistry B, 105
Tae-Young Yoon, Burak Okumuş, Fan Zhang, Y. Shin, T. Ha (2006)
Multiple intermediates in SNARE-induced membrane fusionProceedings of the National Academy of Sciences, 103
D. Lévy, A. Gulik, A. Bluzat, J. Rigaud (1992)
Reconstitution of the sarcoplasmic reticulum Ca(2+)-ATPase: mechanisms of membrane protein insertion into liposomes during reconstitution procedures involving the use of detergents.Biochimica et biophysica acta, 1107 2
Yoosoo Yang, J. Shin, Jung-Mi Oh, Chang Jung, Yunha Hwang, Sehyun Kim, Jun-Seob Kim, Kee-Jung Yoon, J. Ryu, J. Shin, J. Hwang, Tae-Young Yoon, Y. Shin, D. Kweon (2010)
Dissection of SNARE-driven membrane fusion and neuroexocytosis by wedging small hydrophobic molecules into the SNARE zipperProceedings of the National Academy of Sciences, 107
Sascha Martens, M. Kozlov, H. McMahon (2007)
How Synaptotagmin Promotes Membrane FusionScience, 316
Joji Mima, Christopher Hickey, Hao Xu, Y. Jun, W. Wickner (2008)
Reconstituted membrane fusion requires regulatory lipids, SNAREs and synergistic SNARE chaperonesThe EMBO Journal, 27
M. Holt, D. Riedel, A. Stein, C. Schuette, R. Jahn (2008)
Synaptic Vesicles Are Constitutively Active Fusion Machines that Function Independently of Ca2+Current Biology, 18
H. Risselada, Carsten Kutzner, H. Grubmüller (2011)
Caught in the Act: Visualization of SNARE‐Mediated Fusion Events in Molecular DetailChemBioChem, 12
J. Rizo, Xiaocheng Chen, D. Araç (2006)
Unraveling the mechanisms of synaptotagmin and SNARE function in neurotransmitter release.Trends in cell biology, 16 7
T. Hayashi, H. McMahon, S. Yamasaki, T. Binz, Y. Hata, T. Südhof, H. Niemann (1994)
Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assembly.The EMBO Journal, 13
Simon Castorph, S. Henriques, Matthew Holt, Dietmar Riedel, Reinhard Jahn, Tim Salditt (2011)
Synaptic vesicles studied by dynamic light scatteringThe European Physical Journal E, 34
M. Schwartz, A. Merz (2009)
Capture and release of partially zipped trans-SNARE complexes on intact organellesThe Journal of Cell Biology, 185
V. Malinin, B. Lentz (2004)
Energetics of vesicle fusion intermediates: comparison of calculations with observed effects of osmotic and curvature stresses.Biophysical journal, 86 5
《中华放射肿瘤学杂志》编辑部 (2001)
MedlineCurrent Biology, 7
K. Wiederhold, D. Fasshauer (2009)
Is Assembly of the SNARE Complex Enough to Fuel Membrane Fusion?Journal of Biological Chemistry, 284
C. Schuette, K. Hatsuzawa, M. Margittai, A. Stein, D. Riedel, Petra Küster, M. König, C. Seidel, R. Jahn (2004)
Determinants of liposome fusion mediated by synaptic SNARE proteins.Proceedings of the National Academy of Sciences of the United States of America, 101 9
Geert Bogaart, M. Holt, G. Bunt, D. Riedel, F. Wouters, R. Jahn (2010)
One SNARE complex is sufficient for membrane fusionNature structural & molecular biology, 17
A. Stein, A. Radhakrishnan, D. Riedel, D. Fasshauer, R. Jahn (2007)
Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipidsNature Structural &Molecular Biology, 14
Akhil Bhalla, Michael Chicka, W. Tucker, E. Chapman (2006)
Ca2+–synaptotagmin directly regulates t-SNARE function during reconstituted membrane fusionNature Structural &Molecular Biology, 13
Alexander Walter, K. Wiederhold, D. Bruns, D. Fasshauer, J. Sørensen (2010)
Synaptobrevin N-terminally bound to syntaxin–SNAP-25 defines the primed vesicle state in regulated exocytosisThe Journal of Cell Biology, 188
M. Stevens, J. Hoh, T. Woolf (2003)
Insights into the molecular mechanism of membrane fusion from simulation: evidence for the association of splayed tails.Physical review letters, 91 18
H. Scheidt, A. Pampel, Ludwig Nissler, R. Gebhardt, D. Huster (2004)
Investigation of the membrane localization and distribution of flavonoids by high-resolution magic angle spinning NMR spectroscopy.Biochimica et biophysica acta, 1663 1-2
M. Margittai, D. Fasshauer, Stefan Pabst, R. Jahn, R. Langen (2001)
Homo- and Heterooligomeric SNARE Complexes Studied by Site-directed Spin Labeling*The Journal of Biological Chemistry, 276
Dov Lichtenberg, Robert Robson, Edward Dennis (1983)
Solubilization of phospholipids by detergents. Structural and kinetic aspects.Biochimica et biophysica acta, 737 2
Anna Cypionka, A. Stein, Javier Hernández, H. Hippchen, R. Jahn, P. Walla (2009)
Discrimination between docking and fusion of liposomes reconstituted with neuronal SNARE-proteins using FCSProceedings of the National Academy of Sciences, 106
J. Rigaud, D. Lévy (2003)
Reconstitution of membrane proteins into liposomes.Methods in enzymology, 372
Lin Yang, Huey Huang (2002)
Observation of a Membrane Fusion Intermediate StructureScience, 297
Jörg Nikolaus, M. Stöckl, D. Langosch, R. Volkmer, A. Herrmann (2009)
Direct visualization of large and protein-free hemifusion diaphragms.Biophysical journal, 98 7
J. Lakowicz (1983)
Principles of fluorescence spectroscopy
(1126)
Supplementary Materials www.sciencemag.org/cgi/content/full/science.1221976/DC1 Materials and Methods Supplementary Text Figs. S1 to S9 References
T. Weber, B. Zemelman, J. McNew, B. Westermann, M. Gmachl, F. Parlati, T. Söllner, J. Rothman (1998)
SNAREpins: Minimal Machinery for Membrane FusionCell, 92
Raul Guzman, Yvonne Schwarz, J. Rettig, D. Bruns (2010)
SNARE Force Synchronizes Synaptic Vesicle Fusion and Controls the Kinetics of Quantal Synaptic TransmissionThe Journal of Neuroscience, 30
G. Rouser, S. Fkeischer, A. Yamamoto (1970)
Two dimensional then layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots.Lipids, 5 5
L. Chernomordik, M. Kozlov (2008)
Mechanics of membrane fusionNature structural & molecular biology, 15
R. Lefort, J. Duvail, T. Corre, Yuanchun Zhao, D. Morineau (2011)
Phase separation of a binary liquid in anodic aluminium oxide templatesThe European Physical Journal E, 34
D. Fasshauer, Wolfram Antonin, M. Margittai, Stefan Pabst, R. Jahn (1999)
Mixed and Non-cognate SNARE ComplexesThe Journal of Biological Chemistry, 274
Christopher Haluska, K. Riske, V. Marchi-Artzner, J. Lehn, R. Lipowsky, R. Dimova (2006)
Time scales of membrane fusion revealed by direct imaging of vesicle fusion with high temporal resolutionProceedings of the National Academy of Sciences, 103
J. Rigaud, B. Pitard, D. Lévy (1995)
Reconstitution of membrane proteins into liposomes: application to energy-transducing membrane proteins.Biochimica et biophysica acta, 1231 3
R Sutton, D. Fasshauer, R. Jahn, A. Brunger (1998)
Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolutionNature, 395
A. Grafmüller, J. Shillcock, R. Lipowsky (2009)
The fusion of membranes and vesicles: pathway and energy barriers from dissipative particle dynamics.Biophysical journal, 96 7
Tabrez Siddiqui, Olga Vites, A. Stein, R. Heintzmann, R. Jahn, D. Fasshauer (2007)
Determinants of synaptobrevin regulation in membranes.Molecular biology of the cell, 18 6
(1663)
Biochim
Mathias Hofmann, K. Peplowska, J. Rohde, Bernhard Poschner, C. Ungermann, D. Langosch (2006)
Self-interaction of a SNARE transmembrane domain promotes the hemifusion-to-fusion transition.Journal of molecular biology, 364 5
Yibin Xu, Fan Zhang, Z. Su, J. McNew, Y. Shin (2005)
Hemifusion in SNARE-mediated membrane fusionNature Structural &Molecular Biology, 12
A. Stein, G. Weber, M. Wahl, R. Jahn (2009)
Helical extension of the neuronal SNARE complex into the membraneNature, 460
Geert Bogaart, S. Thutupalli, Jelger Risselada, Karsten Meyenberg, M. Holt, D. Riedel, U. Diederichsen, S. Herminghaus, H. Grubmüller, R. Jahn (2011)
Synaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleationNature structural & molecular biology, 18
A. Pobbati, A. Stein, D. Fasshauer (2006)
N- to C-Terminal SNARE Complex Assembly Promotes Rapid Membrane FusionScience, 313
Science – Unpaywall
Published: Jun 1, 2012
Access the full text.
Sign up today, get DeepDyve free for 14 days.