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Dengue Infection in Pregnancy Prevalence, Vertical Transmission, and Pregnancy Outcome

Dengue Infection in Pregnancy Prevalence, Vertical Transmission, and Pregnancy Outcome Dengue Infection in Pregnancy Prevalence, Vertical Transmission, and Pregnancy Outcome Peng Chiong Tan, MRCOG, Geetha Rajasingam, MBBS, Shamala Devi, PhD, and Siti Zawiah Omar, MMed OBJECTIVE: To estimate prevalence rate of recent den- (P.025) compared with dengue IgM–negative women, gue infection in parturients, as well as the vertical trans- all other characteristics were similar. Rates of preterm mission rate, and to compare pregnancy outcomes birth, mode of delivery, postpartum hemorrhage, low among infected women. birth weight, and neonatal outcomes were not different. METHOD: A prospective cohort study was performed. CONCLUSION: Recent dengue infection was demon- Maternal and paired umbilical cord bloods were taken at strated in 2.5% of parturients, with a vertical transmission delivery. A brief questionnaire on febrile illness and rate of 1.6%. Pregnancy outcome of recently infected dengue in pregnancy was completed by participants. The women was not different. samples were sent to a World Health Organization Col- (Obstet Gynecol 2008;111:1111–7) laborating Center for Arbovirus Reference and Research. LEVEL OF EVIDENCE: II Maternal sera were tested with a dengue-specific immu- noglobulin M (IgM) capture test. The paired umbilical engue is the most common mosquito-borne in- cord serum was tested to determine when the maternal sample was positive. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Obstetrics & Gynecology Wolters Kluwer Health

Dengue Infection in Pregnancy Prevalence, Vertical Transmission, and Pregnancy Outcome

Omar, Siti Zawiah
Obstetrics & Gynecology , Volume 111 (5) – May 1, 2008
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ISSN
0029-7844
eISSN
1873-233X
DOI
10.1097/AOG.0b013e31816a49fc
pmid
18448743
Publisher site
See Article on Publisher Site

Abstract

Dengue Infection in Pregnancy Prevalence, Vertical Transmission, and Pregnancy Outcome Peng Chiong Tan, MRCOG, Geetha Rajasingam, MBBS, Shamala Devi, PhD, and Siti Zawiah Omar, MMed OBJECTIVE: To estimate prevalence rate of recent den- (P.025) compared with dengue IgM–negative women, gue infection in parturients, as well as the vertical trans- all other characteristics were similar. Rates of preterm mission rate, and to compare pregnancy outcomes birth, mode of delivery, postpartum hemorrhage, low among infected women. birth weight, and neonatal outcomes were not different. METHOD: A prospective cohort study was performed. CONCLUSION: Recent dengue infection was demon- Maternal and paired umbilical cord bloods were taken at strated in 2.5% of parturients, with a vertical transmission delivery. A brief questionnaire on febrile illness and rate of 1.6%. Pregnancy outcome of recently infected dengue in pregnancy was completed by participants. The women was not different. samples were sent to a World Health Organization Col- (Obstet Gynecol 2008;111:1111–7) laborating Center for Arbovirus Reference and Research. LEVEL OF EVIDENCE: II Maternal sera were tested with a dengue-specific immu- noglobulin M (IgM) capture test. The paired umbilical engue is the most common mosquito-borne in- cord serum was tested to determine when the maternal sample was positive.

Journal

Obstetrics & Gynecology – Wolters Kluwer Health

Published: May 1, 2008

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