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134 Short paper Heme iron from meat and risk of adenocarcinoma of the esophagus and stomach a b b b Mary H. Ward , Amanda J. Cross , Christian C. Abnet , Rashmi Sinha , c c Rodney S. Markin and Dennis D. Weisenburger Iron can cause oxidative stress and DNA damage, and sources was not significantly associated with risk of either heme iron can catalyze endogenous formation of N-nitroso cancer. Our results suggest that high intakes of heme and compounds, which are potent carcinogens. Dietary iron iron from meat may be important dietary risk factors for promotes esophageal cancer incidence in animal studies esophageal and stomach cancer and may partly explain and has been identified as a growth factor for Helicobacter associations with red meat. European Journal of Cancer pylori, an established risk factor for stomach cancer. We Prevention 21:134–138 c 2012 Wolters Kluwer Health | conducted a population-based case–control study of Lippincott Williams & Wilkins. adenocarcinoma of the esophagus (n = 124) and stomach European Journal of Cancer Prevention 2012, 21:134–138 (n = 154) and 449 controls in Nebraska. Heme iron and Keywords: esophageal cancer, heme iron, iron, nutrition, stomach cancer total iron intake were estimated
European Journal of Cancer Prevention – Wolters Kluwer Health
Published: Mar 1, 2012
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