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Heme iron from meat and risk of adenocarcinoma of the esophagus and stomach

Heme iron from meat and risk of adenocarcinoma of the esophagus and stomach 134 Short paper Heme iron from meat and risk of adenocarcinoma of the esophagus and stomach a b b b Mary H. Ward , Amanda J. Cross , Christian C. Abnet , Rashmi Sinha , c c Rodney S. Markin and Dennis D. Weisenburger Iron can cause oxidative stress and DNA damage, and sources was not significantly associated with risk of either heme iron can catalyze endogenous formation of N-nitroso cancer. Our results suggest that high intakes of heme and compounds, which are potent carcinogens. Dietary iron iron from meat may be important dietary risk factors for promotes esophageal cancer incidence in animal studies esophageal and stomach cancer and may partly explain and has been identified as a growth factor for Helicobacter associations with red meat. European Journal of Cancer pylori, an established risk factor for stomach cancer. We Prevention 21:134–138  c 2012 Wolters Kluwer Health | conducted a population-based case–control study of Lippincott Williams & Wilkins. adenocarcinoma of the esophagus (n = 124) and stomach European Journal of Cancer Prevention 2012, 21:134–138 (n = 154) and 449 controls in Nebraska. Heme iron and Keywords: esophageal cancer, heme iron, iron, nutrition, stomach cancer total iron intake were estimated http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Cancer Prevention Wolters Kluwer Health

Heme iron from meat and risk of adenocarcinoma of the esophagus and stomach

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References (30)

Copyright
© 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins
ISSN
0959-8278
eISSN
1473-5709
DOI
10.1097/CEJ.0b013e32834c9b6c
pmid
22044848
Publisher site
See Article on Publisher Site

Abstract

134 Short paper Heme iron from meat and risk of adenocarcinoma of the esophagus and stomach a b b b Mary H. Ward , Amanda J. Cross , Christian C. Abnet , Rashmi Sinha , c c Rodney S. Markin and Dennis D. Weisenburger Iron can cause oxidative stress and DNA damage, and sources was not significantly associated with risk of either heme iron can catalyze endogenous formation of N-nitroso cancer. Our results suggest that high intakes of heme and compounds, which are potent carcinogens. Dietary iron iron from meat may be important dietary risk factors for promotes esophageal cancer incidence in animal studies esophageal and stomach cancer and may partly explain and has been identified as a growth factor for Helicobacter associations with red meat. European Journal of Cancer pylori, an established risk factor for stomach cancer. We Prevention 21:134–138  c 2012 Wolters Kluwer Health | conducted a population-based case–control study of Lippincott Williams & Wilkins. adenocarcinoma of the esophagus (n = 124) and stomach European Journal of Cancer Prevention 2012, 21:134–138 (n = 154) and 449 controls in Nebraska. Heme iron and Keywords: esophageal cancer, heme iron, iron, nutrition, stomach cancer total iron intake were estimated

Journal

European Journal of Cancer PreventionWolters Kluwer Health

Published: Mar 1, 2012

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