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References (36)
-
I. Okamoto, Hiromasa Tsuiki, L. Kenyon, A. Godwin, D. Emlet, M. Holgado-Madruga, I. Lanham, Christopher Joynes, Kim Vo, A. Guha, M. Matsumoto, Y. Ushio, H. Saya, A. Wong (2002)
Proteolytic cleavage of the CD44 adhesion molecule in multiple human tumors.The American journal of pathology, 160 2
-
D. Naor, S. Nedvetzki, Itshak Golan, Lora Melnik, Yoram Faitelson (2002)
CD44 in CancerCritical Reviews in Clinical Laboratory Sciences, 39
-
K. Lehti, Heli Valtanen, S. Wickström, J. Lohi, J. Keski‐oja (2000)
Regulation of Membrane-type-1 Matrix Metalloproteinase Activity by Its Cytoplasmic Domain*The Journal of Biological Chemistry, 275
-
Hiroshi Sato, T. Takino, H. Miyamori (2005)
Roles of membrane‐type matrix metalloproteinase‐1 in tumor invasion and metastasisCancer Science, 96
-
Katarina Wolf, Yi Wu, Yi Wu, Yueying Liu, J. Geiger, E. Tam, E. Tam, C. Overall, M. Stack, P. Friedl (2007)
Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasionNature Cell Biology, 9
-
G. Weber, R. Bronson, J. Ilagan, H. Cantor, R. Schmits, T. Mak (2002)
Absence of the CD44 gene prevents sarcoma metastasis.Cancer research, 62 8
-
Maristte Driessens, Peter Str0eken, N. Erena, M. Valk, E. Rijthoven, Ed Roos (1995)
Targeted disruption of CD44 in MDAY-D2 lymphosarcoma cells has no effect on subcutaneous growth or metastatic capacityThe Journal of Cell Biology, 131
-
M. Kajita, Y. Itoh, T. Chiba, H. Mori, A. Okada, H. Kinoh, M. Seiki (2001)
Membrane-Type 1 Matrix Metalloproteinase Cleaves Cd44 and Promotes Cell MigrationThe Journal of Cell Biology, 153
-
J. Bravo-Cordero, R. Marrero-Diaz, D. Megías, L. Genı́s, Aránzazu García-Grande, María García, A. Arroyo, M. Montoya (2007)
MT1‐MMP proinvasive activity is regulated by a novel Rab8‐dependent exocytic pathwayThe EMBO Journal, 26
-
B. Galvez, Salomón Matías-Román, M. Yáñez‐Mó, F. Sánchez‐Madrid, A. Arroyo (2002)
ECM regulates MT1-MMP localization with β1 or αvβ3 integrins at distinct cell compartments modulating its internalization and activity on human endothelial cellsThe Journal of Cell Biology, 159
-
G. Taraboletti, S. D'Ascenzo, P. Borsotti, R. Giavazzi, A. Pavan, V. Dolo (2002)
Shedding of the matrix metalloproteinases MMP-2, MMP-9, and MT1-MMP as membrane vesicle-associated components by endothelial cells.The American journal of pathology, 160 2
-
B. Annabi, S. Thibeault, R. Moumdjian, R. Béliveau (2004)
Hyaluronan Cell Surface Binding Is Induced by Type I Collagen and Regulated by Caveolae in Glioma Cells*Journal of Biological Chemistry, 279
-
Lurong Zhang, C. Underhill, Lieping Chen (1995)
Hyaluronan on the surface of tumor cells is correlated with metastatic behavior.Cancer research, 55 2
-
S. Tsukita, K. Oishi, N. Sato, J. Sagara, A. Kawai, S. Tsukita (1994)
ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletonsThe Journal of Cell Biology, 126
-
Hiroyuki Nakamura, N. Suenaga, Kaori Taniwaki, H. Matsuki, K. Yonezawa, M. Fujii, Y. Okada, M. Seiki (2004)
Constitutive and Induced CD44 Shedding by ADAM-Like Proteases and Membrane-Type 1 Matrix MetalloproteinaseCancer Research, 64
-
M. Egeblad, Z. Werb (2002)
New functions for the matrix metalloproteinases in cancer progressionNature Reviews Cancer, 2
-
K. Garton, Peter Gough, Elaine Raines (2006)
Emerging roles for ectodomain shedding in the regulation of inflammatory responsesJournal of Leukocyte Biology, 79
-
E. MariStteH., N. Erena, A. Valk, El thoven, Ed (2002)
Targeted Disruption of CD 44 in MDAY-D 2 Lymphosarcoma Cells Has No Effect on Subcutaneous Growth or Metastatic Capacity -
Y. Itoh, M. Seiki (2006)
MT1‐MMP: A potent modifier of pericellular microenvironmentJournal of Cellular Physiology, 206
-
R. Marhaba, M. Zöller, M. Zöller (2003)
CD44 in Cancer Progression: Adhesion, Migration and Growth RegulationJournal of Molecular Histology, 35
-
Kerstin Maaser, Katarina Wolf, C. Klein, B. Niggemann, K. Zänker, Eva-Bettina Bröcker, Peter Friedl (1999)
Functional hierarchy of simultaneously expressed adhesion receptors: integrin alpha2beta1 but not CD44 mediates MV3 melanoma cell migration and matrix reorganization within three-dimensional hyaluronan-containing collagen matrices.Molecular biology of the cell, 10 10
-
D. Megías, Raquel Marrero, Borja Peso, María García, J. Bravo-Cordero, Aránzazu García-Grande, Andrés Santos, M. Montoya (2009)
Novel lambda FRET spectral confocal microscopy imaging methodMicroscopy Research and Technique, 72
-
Isamu Okamoto, Y. Kawano, M. Matsumoto, M. Suga, K. Kaibuchi, M. Ando, H. Saya (1999)
Regulated CD44 Cleavage under the Control of Protein Kinase C, Calcium Influx, and the Rho Family of Small G Proteins*The Journal of Biological Chemistry, 274
-
B. Toole, C. Biswas, J. Gross (1979)
Hyaluronate and invasiveness of the rabbit V2 carcinoma.Proceedings of the National Academy of Sciences of the United States of America, 76 12
-
J. Legg, C. Lewis, M. Parsons, T. Ng, C. Isacke (2002)
A novel PKC-regulated mechanism controls CD44–ezrin association and directional cell motilityNature Cell Biology, 4
-
E. Lara-Pezzi, J. Serrador, M. Montoya, D. Zamora, M. Yáñez‐Mó, M. Carretero, H. Furthmayr, F. Sánchez‐Madrid, M. López-Cabrera (2001)
The hepatitis B virus X protein (HBx) induces a migratory phenotype in a CD44‐dependent manner: Possible role of HBx in invasion and metastasisHepatology, 33
-
P. Friedl, K. Maaser, C. Klein, B. Niggemann, G. Krohne, K. Zänker (1997)
Migration of highly aggressive MV3 melanoma cells in 3-dimensional collagen lattices results in local matrix reorganization and shedding of alpha2 and beta1 integrins and CD44.Cancer research, 57 10
-
Rubén Bartolomé, Isabel Molina-Ortiz, R. Samaniego, P. Sánchez-Mateos, X. Bustelo, J. Teixidó (2006)
Activation of Vav/Rho GTPase signaling by CXCL12 controls membrane-type matrix metalloproteinase-dependent melanoma cell invasion.Cancer research, 66 1
-
N. Suenaga, H. Mori, Y. Itoh, M. Seiki (2005)
CD44 binding through the hemopexin-like domain is critical for its shedding by membrane-type 1 matrix metalloproteinaseOncogene, 24
-
H. Nakahara, L. Howard, Erik Thompson, Hiroshi Sato, M. Seiki, Y. Yeh, Wen‐Tien Chen (1997)
Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion.Proceedings of the National Academy of Sciences of the United States of America, 94 15
-
H. Mori, T. Tomari, N. Koshikawa, M. Kajita, Y. Itoh, Hiroshi Sato, H. Tojo, I. Yana, M. Seiki (2002)
CD44 directs membrane‐type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin‐like domainThe EMBO Journal, 21
-
Mylène Vivinus-Nebot, P. Rousselle, J. Breittmayer, Claire Cenciarini, S. Berrih-Aknin, S. Spong, P. Nokelainen, F. Cottrez, M. Marinkovich, A. Bernard (2004)
Mature Human Thymocytes Migrate on Laminin-5 with Activation of Metalloproteinase-14 and Cleavage of CD441The Journal of Immunology, 172
-
O. Nagano, H. Saya (2004)
Mechanism and biological significance of CD44 cleavageCancer Science, 95
-
P. Friedl, Katarina Wolf (2003)
Tumour-cell invasion and migration: diversity and escape mechanismsNature Reviews Cancer, 3
-
Weigang Wang, J. Wyckoff, Victoria Frohlich, Y. Oleynikov, S. Hüttelmaier, J. Zavadil, L. Cermak, E. Bottinger, R. Singer, J. White, J. Segall, J. Condeelis (2002)
Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling.Cancer research, 62 21
-
I. Okamoto, Y. Kawano, Hiromasa Tsuiki, J. Sasaki, M. Nakao, M. Matsumoto, M. Suga, M. Ando, M. Nakajima, H. Saya (1999)
CD44 cleavage induced by a membrane-associated metalloprotease plays a critical role in tumor cell migrationOncogene, 18
- Publisher
- Wiley
- Copyright
- Copyright © 2009 Wiley Subscription Services, Inc., A Wiley Company
- ISSN
- 1949-3584
- eISSN
- 1949-3592
- DOI
- 10.1002/cm.20325
- Publisher site
- See Article on Publisher Site
Abstract
The adhesion molecule CD44 and the membrane‐type matrix metalloproteinase MT1‐MMP act coordinately in tumor cells to promote cell invasion through a yet unclear mechanism. We are interested in studying the interplay between CD44 and MT1‐MMP in carcinoma cells embedded in HA containing three‐dimensional collagen I matrices (3D HA‐Col I) by time‐lapse confocal microscopy imaging. Here we report the in vivo interaction between CD44 and MT1‐MMP, revealed by fluorescence resonance energy transfer (FRET) microscopy. MT1‐MMP interacts with CD44 preferentially at the trailing edge of the invading tumor cells during rear retraction and on membrane fragments released during the invasion process. A fluorescent biosensor designed to monitor the proteolytic processing of CD44 by live cell imaging demonstrates that cleavage of the CD44 extracellular domain is enriched in the retracting rear ends of invasive tumor cells. Invasion assays showed that MT1‐MMP mediates CD44‐dependent tumor‐cell invasion, whereas CD44 is not essential for MT1‐MMP‐mediated invasion of 3D HA‐Col I matrices. Together, our results support a role for MT1‐MMP in cell retraction during CD44‐mediated cell invasion. Cell. Motil. Cytoskelton 2008. © 2008 Wiley‐Liss, Inc.
Journal
Cytoskeleton – Wiley
Published: Jan 1, 2009
Keywords: ; ; ; ; ;