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References (29)
-
K. Jones, J. Senft (1985)
An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 33
-
H. Fearnhead, D. Dinsdale, G. Cohen (1995)
An interleukin‐1β‐converting enzyme‐like protease is a common mediator of apoptosis in thymocytesFEBS Letters, 375
-
V. Longthorne, G.T. Williams (1997)
Caspase activity is required for commitment to Fas‐mediated apoptosisThe EMBO Journal, 16
-
M. Hampton, S. Orrenius (1997)
Dual regulation of caspase activity by hydrogen peroxide: implications for apoptosisFEBS Letters, 414
-
M. Jacobson, M. Weil (1996)
Role of Ced-3/ICE-family proteases in staurosporine-induced programmed cell deathThe Journal of Cell Biology, 133
-
P. Henkart (1996)
ICE family proteases: mediators of all apoptotic cell death?Immunity, 4 3
-
T. Hirsch, P. Marchetti, S. Susin, B. Dallaporta, N. Zamzami, I. Marzo, M. Geuskens, G. Kroemer (1997)
The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell deathOncogene, 15
-
M. Leist, P. Nicotera (1997)
The shape of cell death.Biochemical and biophysical research communications, 236 1
-
Z. Darżynkiewicz, Z. Darżynkiewicz, G. Juan, Xun Li, W. Gorczyca, T. Murakami, F. Traganos (1997)
Cytometry in cell necrobiology: analysis of apoptosis and accidental cell death (necrosis).Cytometry, 27 1
-
D. Nicholson, N. Thornberry (1997)
Caspases: killer proteases.Trends in biochemical sciences, 22 8
-
M'hammed Sarih, V. Souvannavong, A. Adam (1993)
Nitric oxide synthase induces macrophage death by apoptosis.Biochemical and biophysical research communications, 191 2
-
A. Alam, M. Braun, F. Hartgers, S. Lesage, L. Cohen, P. Hugo, F. Denis, R. Sékaly (1997)
Specific Activation of the Cysteine Protease CPP32 during the Negative Selection of T Cells in the ThymusThe Journal of Experimental Medicine, 186
-
M. McCarthy, L. Rubin, K. Philpott (1997)
Involvement of caspases in sympathetic neuron apoptosis.Journal of cell science, 110 ( Pt 18)
-
Vicente Medina, Belinda Edmonds, Graeme Young, R. James, Sarah Appleton, P. Zalewski (1997)
Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway.Cancer research, 57 17
-
V. Illera, C. Perandones, L. Stunz, D. Mower, R. Ashman (1993)
Apoptosis in splenic B lymphocytes. Regulation by protein kinase C and IL-4.Journal of immunology, 151 6
-
S. An, K. Knox (1996)
Ligation of CD40 rescues Ramos‐Burkitt lymphoma B cells from calcium ionophore‐ and antigen receptor‐triggered apoptosis by inhibiting activation of the cysteine protease CPP32/Yama and cleavage of its substrate PARPFEBS Letters, 386
-
R. Ashman, David Peckham, L. Stunz (1996)
Fc receptor off-signal in the B cell involves apoptosis.Journal of immunology, 157 1
-
E. Alnemri (1997)
Mammalian cell death proteases: A family of highly conserved aspartate specific cysteine proteasesJournal of Cellular Biochemistry, 64
-
M. Newell, J. Vanderwall, K. Beard, J. Freed (1993)
Ligation of major histocompatibility complex class II molecules mediates apoptotic cell death in resting B lymphocytes.Proceedings of the National Academy of Sciences of the United States of America, 90 22
-
G. Cohen (1997)
Caspases: the executioners of apoptosis.The Biochemical journal, 326 ( Pt 1)
-
A. Wyllie, J. Kerr, A. Currie (1980)
Cell death: the significance of apoptosis.International review of cytology, 68
-
T. Ohta, T. Kinoshita, M. Naito, T. Nozaki, M. Masutani, T. Tsuruo, A. Miyajima (1997)
Requirement of the Caspase-3/CPP32 Protease Cascade for Apoptotic Death following Cytokine Deprivation in Hematopoietic Cells*The Journal of Biological Chemistry, 272
-
B. Bellosillo, M. Dalmau, D. Colomer, J. Gil (1997)
Involvement of CED-3/ICE proteases in the apoptosis of B-chronic lymphocytic leukemia cells.Blood, 89 9
-
E. Bonfoco, D. Krainc (1995)
Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures.Proceedings of the National Academy of Sciences of the United States of America, 92 16
-
Y. Eguchi, S. Shimizu, Y. Tsujimoto (1997)
Intracellular ATP levels determine cell death fate by apoptosis or necrosis.Cancer research, 57 10
-
Douglas Miller, J. Myerson, J. Becker (1997)
The interleukin‐1β converting enzyme family of cysteine proteasesJournal of Cellular Biochemistry, 64
-
R. Barge, R. Willemze, P. Vandenabeele, W. Fiers, R. Beyaert (1997)
Differential involvement of caspases in apoptosis of myeloid leukemic cells induced by chemotherapy versus growth factor withdrawalFEBS Letters, 409
-
D. Vaux, A. Strasser (1996)
The molecular biology of apoptosis.Proceedings of the National Academy of Sciences of the United States of America, 93 6
-
D. Nicholson, Ambereen Ali, N. Thornberry, J. Vaillancourt, Connie Ding, M. Gallant, Y. Gareau, P. Griffin, M. Labelle, Y. Lazebnik, N. Munday, S. Raju, M. Smulson, T. Yamin, Violeta Yu, Douglas Miller (1995)
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosisNature, 376
- Publisher
- Wiley
- Copyright
- © 2015 Federation of European Biochemical Societies
- eISSN
- 1873-3468
- DOI
- 10.1016/S0014-5793(98)00252-X
- Publisher site
- See Article on Publisher Site
Abstract
The role of caspases in B lymphocyte cell death was investigated by using two broad spectrum inhibitors of the caspase family, Z‐Asp‐cmk and Z‐VAD‐fmk. They totally prevented spontaneous and drug‐induced apoptosis and inhibited the CPP32/caspase‐3‐like activity exhibited by apoptotic cells. However, the suppression of apoptosis was not associated with a long‐term increase of cell survival, but conversely, with a switch from apoptotic death to the necrotic form. These results strongly suggest that apoptosis and necrosis share common initiation pathways, the final issue being determined by the presence of an active caspase.
Journal
Febs Letters – Wiley
Published: Mar 27, 1998
Keywords: ; ; ; ; ; ; ; ;