Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 7-Day Trial for You or Your Team.

Learn More →

Redefinition of Myocardial Infarction Prospective Evaluation in the Community

Redefinition of Myocardial Infarction Prospective Evaluation in the Community Epidemiology Redefinition of Myocardial Infarction Prospective Evaluation in the Community Véronique L. Roger, MD, MPH; Jill M. Killian, BS; Susan A. Weston, MS; Allan S. Jaffe, MD; Jan Kors, PhD; Paula J. Santrach, MD; Hugh Tunstall-Pedoe, MD; Steven J. Jacobsen, MD, PhD Background—The 2000 European Society of Cardiology/American College of Cardiology definition for myocardial infarction (MI) combines ischemic symptoms, electrocardiographic changes, and troponin rather than creatine kinase levels. The use of troponins will increase the detection of MI by a magnitude to be quantified, and the clinical acceptance of the new definition is unknown. Method and Results—Subjects presenting to an Olmsted County facility with a troponin T value 0.03 ng/mL between November 2002 and March 2005 were prospectively classified through the use of standardized MI criteria, relying on cardiac pain, Minnesota coding of the ECG, and troponin, creatine kinase, and its MB fraction measured simultaneously. Through the use of dynamic changes in troponin, 538 MIs were identified versus 327 with creatine kinase and 427 with only the MB fraction of creatine kinase. This represents a 74% (95% confidence interval [CI], 69% to 79%) increase above the number of MIs identified with creatine kinase and a 41% (95% CI, 37% http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Circulation Wolters Kluwer Health

Redefinition of Myocardial Infarction Prospective Evaluation in the Community

Jacobsen, Steven J.
Circulation , Volume 114 (8) – Aug 1, 2006
Download PDF
8 pages

Loading next page...
 
/lp/wolters-kluwer-health/redefinition-of-myocardial-infarction-prospective-evaluation-in-the-oST00jSiva

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

ISSN
0009-7322
eISSN
1524-4539
DOI
10.1161/CIRCULATIONAHA.106.627505
pmid
16908764
Publisher site
See Article on Publisher Site

Abstract

Epidemiology Redefinition of Myocardial Infarction Prospective Evaluation in the Community Véronique L. Roger, MD, MPH; Jill M. Killian, BS; Susan A. Weston, MS; Allan S. Jaffe, MD; Jan Kors, PhD; Paula J. Santrach, MD; Hugh Tunstall-Pedoe, MD; Steven J. Jacobsen, MD, PhD Background—The 2000 European Society of Cardiology/American College of Cardiology definition for myocardial infarction (MI) combines ischemic symptoms, electrocardiographic changes, and troponin rather than creatine kinase levels. The use of troponins will increase the detection of MI by a magnitude to be quantified, and the clinical acceptance of the new definition is unknown. Method and Results—Subjects presenting to an Olmsted County facility with a troponin T value 0.03 ng/mL between November 2002 and March 2005 were prospectively classified through the use of standardized MI criteria, relying on cardiac pain, Minnesota coding of the ECG, and troponin, creatine kinase, and its MB fraction measured simultaneously. Through the use of dynamic changes in troponin, 538 MIs were identified versus 327 with creatine kinase and 427 with only the MB fraction of creatine kinase. This represents a 74% (95% confidence interval [CI], 69% to 79%) increase above the number of MIs identified with creatine kinase and a 41% (95% CI, 37%

Journal

Circulation – Wolters Kluwer Health

Published: Aug 1, 2006

There are no references for this article.