Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 7-Day Trial for You or Your Team.

Learn More →

Typhlitis Associated With Docetaxel Treatment

Typhlitis Associated With Docetaxel Treatment U/L). An abdominal x ray showed small as our patient, are receiving steroids as bowel distension. He was started on in- part of their treatment regimen. travenous fluids, ceftazidime (2 g every Overwhelming sepsis due to C. sep- CORRESPONDENCE 8 hours), and amikacin (500 mg every ticum in patients with neutropenia is al- 12 hours). In 3 hours, he went into most always associated with typhlitis shock and, despite all supportive mea- (7,8). It has a very poor prognosis, and sures, died 11 hours following admis- early medical intervention is necessary sion. Blood cultures grew C. septicum Typhlitis Associated With to cure some of these patients. Early that was sensitive to cephalosporins and suspicion of this condition might help to Docetaxel Treatment aminoglycosides. A postmortem ex- initiate effective antibiotic treatment as amination showed intense edema of the soon as possible. intestinal wall, air within the mucosa The knowledge that potent new drugs Typhlitis, previously known as a seri- and submucosa, necrosis without in- such as docetaxel, which has been as- ous complication of hematologic malig- flammatory infiltrate, and extensive sociated with early, short, but profound nant and nonmalignant conditions {12), bacterial infiltration that affected pri- neutropenia, might cause typhlitis http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JNCI: Journal of the National Cancer Institute Oxford University Press

Typhlitis Associated With Docetaxel Treatment

Download PDF
2 pages

Loading next page...
 
/lp/oxford-university-press/typhlitis-associated-with-docetaxel-treatment-obduydqEuM

References (7)

Publisher
Oxford University Press
Copyright
© Oxford University Press
ISSN
0027-8874
eISSN
1460-2105
DOI
10.1093/jnci/88.15.1078
Publisher site
See Article on Publisher Site

Abstract

U/L). An abdominal x ray showed small as our patient, are receiving steroids as bowel distension. He was started on in- part of their treatment regimen. travenous fluids, ceftazidime (2 g every Overwhelming sepsis due to C. sep- CORRESPONDENCE 8 hours), and amikacin (500 mg every ticum in patients with neutropenia is al- 12 hours). In 3 hours, he went into most always associated with typhlitis shock and, despite all supportive mea- (7,8). It has a very poor prognosis, and sures, died 11 hours following admis- early medical intervention is necessary sion. Blood cultures grew C. septicum Typhlitis Associated With to cure some of these patients. Early that was sensitive to cephalosporins and suspicion of this condition might help to Docetaxel Treatment aminoglycosides. A postmortem ex- initiate effective antibiotic treatment as amination showed intense edema of the soon as possible. intestinal wall, air within the mucosa The knowledge that potent new drugs Typhlitis, previously known as a seri- and submucosa, necrosis without in- such as docetaxel, which has been as- ous complication of hematologic malig- flammatory infiltrate, and extensive sociated with early, short, but profound nant and nonmalignant conditions {12), bacterial infiltration that affected pri- neutropenia, might cause typhlitis

Journal

JNCI: Journal of the National Cancer Institute – Oxford University Press

Published: Aug 7, 1996

There are no references for this article.