R. Wolcott, D. Rhoads, S. Dowd (2008)
Biofilms and chronic wound inflammation.Journal of wound care, 17 8
S. Werner, R. Grose (2003)
Regulation of wound healing by growth factors and cytokines.Physiological reviews, 83 3
J. Richard, C. Parer-Richard, J. Daurès, Sophie Clouet, D. Vannereau, J. Bringer, M. Rodier, Claudine Jacob, M. Comte-Bardonnet (1995)
Effect of Topical Basic Fibroblast Growth Factor on the Healing of Chronic Diabetic Neuropathic Ulcer of the foot: A pilot, randomized, double-blind, placebo-controlled studyDiabetes Care, 18
K. Rodgers, L. Bolton, S. Verco, G. diZerega (2015)
NorLeu3-Angiotensin (1-7) [DSC127] as a Therapy for the Healing of Diabetic Foot Ulcers.Advances in wound care, 4 6
Caitlin Garwood, J. Steinberg, P. Kim (2015)
Bioengineered alternative tissues in diabetic wound healing.Clinics in podiatric medicine and surgery, 32 1
Guanghui An, Wenhui Li, Tao Yan, Shitong Li (2014)
Estrogen Rapidly Enhances Incisional Pain of Ovariectomized Rats Primarily through the G Protein-Coupled Estrogen ReceptorInternational Journal of Molecular Sciences, 15
(2006)
bloodjournal.hematologylibrary.org at PENN STATE UNIVERSITY on February 21, 2013. For personal use only. The cytoprotective protein C pathway
Y. Sogabe, M. Abe, Y. Yokoyama, O. Ishikawa (2006)
Basic fibroblast growth factor stimulates human keratinocyte motility by Rac activationWound Repair and Regeneration, 14
G. Ashcroft, M. Horan, M. Ferguson (1995)
The effects of ageing on cutaneous wound healing in mammals.Journal of anatomy, 187 ( Pt 1)
S. Eming, Paul Martin, M. Tomic-Canic (2014)
Wound repair and regeneration: Mechanisms, signaling, and translationScience Translational Medicine, 6
NagarajaS., WallqvistA., ReifmanJ., MitrophanovA.Y. (2014)
Computational approach to characterize causative factors and molecular indicators of chronic wound inflammationJ. Immunol., 192
E. Mudge (2015)
Recent accomplishments in wound healingInternational Wound Journal, 12
H. Uchi, A. Igarashi, K. Urabe, T. Koga, J. Nakayama, R. Kawamori, K. Tamaki, H. Hirakata, T. Ohura, M. Furue (2009)
Clinical efficacy of basic fibroblast growth factor (bFGF) for diabetic ulcer.European journal of dermatology : EJD, 19 5
G. James, E. Swogger, R. Wolcott, E. Pulcini, P. Secor, Jennifer Sestrich, J. Costerton, P. Stewart (2008)
Biofilms in chronic woundsWound Repair and Regeneration, 16
J. Brockes, Anoop Kumar, C. Velloso (2001)
Regeneration as an evolutionary variableJournal of Anatomy, 199
K. Meier, L. Nanney (2006)
Emerging new drugs for wound repairExpert Opinion on Emerging Drugs, 11
Hi-Jin You, Seung-Kyu Han (2014)
Cell Therapy for Wound HealingJournal of Korean Medical Science, 29
L. Toledo-Pereyra, F. López-Neblina, A. Toledo (2003)
Reactive oxygen species and molecular biology of ischemia/reperfusion.Annals of transplantation, 9 1
B. Mast, G. Schultz (1996)
Interactions of cytokines, growth factors, and proteases in acute and chronic woundsWound Repair and Regeneration, 4
V. Falanga (2005)
Wound healing and its impairment in the diabetic footThe Lancet, 366
A. Seekamp, M. Mulligan, G. Till, P. Ward (1993)
Requirements for neutrophil products and L-arginine in ischemia-reperfusion injury.The American journal of pathology, 142 4
Pranita Sarangi, Hyun-wook Lee, Minsoo Kim (2010)
Activated protein C action in inflammationBritish Journal of Haematology, 148
Aruna Wijewardena, Elle Vandervord, Sepehr Lajevardi, J. Vandervord, C. Jackson (2011)
Combination of Activated Protein C and Topical Negative Pressure Rapidly Regenerates Granulation Tissue Over Exposed Bone to Heal Recalcitrant Orthopedic WoundsThe International Journal of Lower Extremity Wounds, 10
M. Hershcovitch, D. Hom (2012)
Update in wound healing in facial plastic surgery.Archives of facial plastic surgery, 14 6
M. Robson, L. Phillips, W. Lawrence, Jon Bishop, Jordan Youngerman, P. Hayward, L. Broemeling, J. Heggers (1992)
The Safety and Effect of Topically Applied Recombinant Basic Fibroblast Growth Factor on the Healing of Chronic Pressure SoresAnnals of Surgery, 216
GurtnerG.C., WernerS., BarrandonY., LongakerM.T. (2008)
Wound repair and regenerationNature, 453
U. Rowlatt (1979)
Intrauterine wound healing in a 20 week human fetusVirchows Archiv A, 381
MosnierL.O., ZlokovicB.V., GriffinJ.H. (2006)
The cytoprotective protein C pathwayBlood, 109
Anaya-PradoR., Toledo-PereyraL.H., LentschA.B., WardP.A. (2002)
Ischemia/reperfusion injuryJ. Surg. Res., 105
SimonP.E., outranH.A., IIIT. Romo, PaffordW., PearsonJ.M., YalamanchiliH., ZoumalanR.A. (2014)
Skin Wound Healing
Martí-Carvajal Aj, G. Salanti, Cardona Af (2009)
Human recombinant activated protein C for severe sepsis (Review)
W. Veer, M. Bloemen, M. Ulrich, G. Molema, P. Zuijlen, E. Middelkoop, F. Niessen (2009)
Potential cellular and molecular causes of hypertrophic scar formation.Burns : journal of the International Society for Burn Injuries, 35 1
A. Gosain, L. DiPietro (2004)
Aging and Wound HealingWorld Journal of Surgery, 28
J. Grey, K. Harding, S. Enoch (2006)
Venous and arterial leg ulcersBMJ : British Medical Journal, 332
K. Whitmont, K. McKelvey, G. Fulcher, I. Reid, L. March, M. Xue, A. Cooper, C. Jackson (2015)
Treatment of chronic diabetic lower leg ulcers with activated protein C: a randomised placebo‐controlled, double‐blind pilot clinical trialInternational Wound Journal, 12
M. Ferguson, S. O'Kane (2004)
Scar-free healing: from embryonic mechanisms to adult therapeutic intervention.Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 359 1445
K. Whitmont, G. Fulcher, I. Reid, M. Xue, K. McKelvey, Y. Xie, M. Aboud, C. Ward, M. Smith, A. Cooper, L. March, C. Jackson (2013)
Low Circulating Protein C Levels Are Associated with Lower Leg Ulcers in Patients with DiabetesBioMed Research International, 2013
N. Adzick, H. Lorenz (1994)
Cells, Matrix, Growth Factors, and the Surgeon The Biology of Scarless Fetal Wound RepairAnnals of Surgery, 220
B. Eckes, R. Nischt, T. Krieg (2010)
Cell-matrix interactions in dermal repair and scarringFibrogenesis & Tissue Repair, 3
S. Schreml, R. Szeimies, L. Prantl, S. Karrer, M. Landthaler, P. Babilas (2010)
Oxygen in acute and chronic wound healingBritish Journal of Dermatology, 163
J. Berlanga-Acosta, G. Schultz, Ernesto López-Mola, G. Guillén-Nieto, Marianela García-Siverio, Luís Herrera-Martínez (2012)
Glucose Toxic Effects on Granulation Tissue Productive Cells: The Diabetics' Impaired HealingBioMed Research International, 2013
C. Sen, G. Gordillo, Sashwati Roy, R. Kirsner, L. Lambert, T. Hunt, F. Gottrup, G. Gurtner, M. Longaker (2009)
Human skin wounds: A major and snowballing threat to public health and the economyWound Repair and Regeneration, 17
Amit Soneja, M. Drews, T. Malinski (2005)
Role of nitric oxide, nitroxidative and oxidative stress in wound healing.Pharmacological reports : PR, 57 Suppl
Tatiana Demidova-Rice, Michael Hamblin, I. Herman (2012)
Acute and impaired wound healing: pathophysiology and current methods for drug delivery, part 1: normal and chronic wounds: biology, causes, and approaches to care.Advances in skin & wound care, 25 7
(2016)
https://www
C. Engeland, J. Bosch, J. Cacioppo, P. Marucha (2006)
Mucosal wound healing: the roles of age and sex.Archives of surgery, 141 12
Y. Kusumanto, V. Weel, N. Mulder, A. Smit, Jjam Dungen, J. Hooymans, W. Sluiter, R. Tio, Paul Quax, R. Gans, R. Dullaart, G. Hospers (2006)
Treatment with intramuscular vascular endothelial growth factor gene compared with placebo for patients with diabetes mellitus and critical limb ischemia: a double-blind randomized trial.Human gene therapy, 17 6
Anna Szpaderska, L. DiPietro (2005)
Inflammation in surgical wound healing: friend or foe?Surgery, 137 5
R. Goldman (2004)
Growth Factors and Chronic Wound Healing: Past, Present, and FutureAdvances in Skin & Wound Care, 17
J. Li, Juan Chen, R. Kirsner (2007)
Pathophysiology of acute wound healing.Clinics in dermatology, 25 1
Cheryl Bansal, R. Scott, D. Stewart, C. Cockerell (2005)
Decubitus ulcers: A review of the literatureInternational Journal of Dermatology, 44
P. Bonham (2003)
Assessment and management of patients with venous, arterial, and diabetic/neuropathic lower extremity wounds.AACN clinical issues, 14 4
G. Ashcroft, G. Ashcroft, T. Greenwell-Wild, M. Horan, S. Wahl, M. Ferguson (1999)
Topical estrogen accelerates cutaneous wound healing in aged humans associated with an altered inflammatory response.The American journal of pathology, 155 4
(2012)
Wound prevalence and wound
R. Sibbald, K. Woo (2008)
The biology of chronic foot ulcers in persons with diabetesDiabetes/Metabolism Research and Reviews, 24
S. Volk, M. Bohling (2013)
Comparative wound healing—Are the small animal veterinarian's clinical patients an improved translational model for human wound healing research?Wound Repair and Regeneration, 21
Paul Martin (1997)
Wound Healing--Aiming for Perfect Skin Regeneration, 276
R. Rudolph (1979)
Location of the force of wound contraction.Surgery, gynecology & obstetrics, 148 4
R. Blakytny, E. Jude (2006)
The molecular biology of chronic wounds and delayed healing in diabetesDiabetic Medicine, 23
C. Jackson, M. Xue, Patrick Thompson, Ross Davey, K. Whitmont, Susan Smith, N. Buisson-Legendre, T. Sztynda, Louise Furphy, A. Cooper, P. Sambrook, L. March (2005)
Activated protein C prevents inflammation yet stimulates angiogenesis to promote cutaneous wound healingWound Repair and Regeneration, 13
T. Hurd (2013)
Understanding the financial benefits of optimising wellbeing in patients living with a wound R E V I E W
G. Ashcroft, S. Mills, J. Ashworth (2004)
Ageing and wound healingBiogerontology, 3
L. Osment (1975)
The skin in wound healing
S. Julovi, M. Xue, S. Dervish, P. Sambrook, L. March, C. Jackson (2011)
Protease activated receptor-2 mediates activated protein C-induced cutaneous wound healing via inhibition of p38.The American journal of pathology, 179 5
DriscollP. (2013)
Wound prevalence and wound management, 2012–2020
I. Darby, O. Skalli, G. Gabbiani (1990)
Alpha-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing.Laboratory investigation; a journal of technical methods and pathology, 63 1
L. Connelly, M. Palacios-Callender, C. Ameixa, S. Moncada, A. Hobbs (2001)
Biphasic Regulation of NF-κB Activity Underlies the Pro- and Anti-Inflammatory Actions of Nitric Oxide1The Journal of Immunology, 166
M. Uchiba, K. Okajima, Y. Oike, Yasuhiro Ito, K. Fukudome, H. Isobe, T. Suda (2004)
Activated Protein C Induces Endothelial Cell Proliferation by Mitogen-Activated Protein Kinase Activation In Vitro and Angiogenesis In VivoCirculation Research: Journal of the American Heart Association, 95
A. Saaristo, T. Tammela, Anniina Farkkila, M. Kärkkäinen, E. Suominen, S. Yla-Herttuala, K. Alitalo (2006)
Vascular endothelial growth factor-C accelerates diabetic wound healing.The American journal of pathology, 169 3
(1998)
Molecular analysis of the environment of healing and chronic wounds: Cytokines, proteases, and growth factors
C. Noli, A. Miolo (2001)
The mast cell in wound healing.Veterinary dermatology, 12 6
M. McGrath, R. Simon (1983)
Wound Geometry and the Kinetics of Wound ContractionPlastic and Reconstructive Surgery, 72
K. Whitmont, I. Reid, S. Tritton, L. March, M. Xue, Michael Lee, G. Fulcher, P. Sambrook, Eric Slobedman, A. Cooper, C. Jackson (2008)
Treatment of chronic leg ulcers with topical activated protein C.Archives of dermatology, 144 11
Stephan Barrientos, Olivera Stojadinović, M. Golinko, H. Brem, M. Tomic-Canic (2008)
PERSPECTIVE ARTICLE: Growth factors and cytokines in wound healingWound Repair and Regeneration, 16
T. Dinh, S. Braunagel, B. Rosenblum (2015)
Growth factors in wound healing: the present and the future?Clinics in podiatric medicine and surgery, 32 1
J. Trent, A. Falabella, W. Eaglstein, R. Kirsner (2005)
Venous ulcers: pathophysiology and treatment options.Ostomy/wound management, 51 5
(2008)
Genentech Announces Full Year and Fourth Quarter 2007 Results
H. Sorg, Y. Harder, C. Krueger, K. Reimers, P. Vogt (2013)
The Nonhematopoietic Effects of Erythropoietin in Skin Regeneration and Repair: From Basic Research to Clinical UseMedicinal Research Reviews, 33
S. Eming, T. Krieg, J. Davidson (2007)
Inflammation in wound repair: molecular and cellular mechanisms.The Journal of investigative dermatology, 127 3
R. Nunan, K. Harding, Paul Martin (2014)
Clinical challenges of chronic wounds: searching for an optimal animal model to recapitulate their complexityDisease Models & Mechanisms, 7
Thomas FACS (2004)
Understanding chronic wounds: a unifying hypothesis on their pathogenesis and implications for therapy.American journal of surgery, 187 5A
S. Kapila, I. Reid, S. Dixit, Greg Fulcher, Lyn March, C. Jackson, A. Cooper (2014)
Use of dermal injection of activated protein C for treatment of large chronic wounds secondary to pyoderma gangrenosumClinical and Experimental Dermatology, 39
Ge Zhao, M. Usui, Soyeon Lippman, G. James, P. Stewart, P. Fleckman, J. Olerud (2013)
Biofilms and Inflammation in Chronic Wounds.Advances in wound care, 2 7
G. Ashcroft, M. Horan, M. Ferguson (1997)
Aging is associated with reduced deposition of specific extracellular matrix components, an upregulation of angiogenesis, and an altered inflammatory response in a murine incisional wound healing model.The Journal of investigative dermatology, 108 4
L. Mosnier, R. Sinha, L. Burnier, Eveline Bouwens, J. Griffin (2012)
Biased agonism of protease-activated receptor 1 by activated protein C caused by noncanonical cleavage at Arg46.Blood, 120 26
R. Diegelmann, M. Evans (2004)
Wound healing: an overview of acute, fibrotic and delayed healing.Frontiers in bioscience : a journal and virtual library, 9
A. Desmoulire, M. Redard, I. Darby, G. Gabbiani (1995)
Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar.The American journal of pathology, 146 1
M. Fonder, G. Lazarus, D. Cowan, Barbara Aronson-Cook, Angela Kohli, A. Mamelak (2008)
Treating the chronic wound: A practical approach to the care of nonhealing wounds and wound care dressings.Journal of the American Academy of Dermatology, 58 2
G. Schultz, R. Sibbald, V. Falanga, E. Ayello, C. Dowsett, K. Harding, M. Romanelli, M. Stacey, L. Téot, W. Vanscheidt (2003)
Wound bed preparation: a systematic approach to wound managementWound Repair and Regeneration, 11
J. Gouin, Liisa Hantsoo, J. Kiecolt-Glaser (2008)
Immune Dysregulation and Chronic Stress among Older Adults: A ReviewNeuroimmunomodulation, 15
M. Xue, C. Jackson (2015)
Extracellular Matrix Reorganization During Wound Healing and Its Impact on Abnormal Scarring.Advances in wound care, 4 3
A. Colwell, T. Krummel, M. Longaker, H. Lorenz (2006)
An In Vivo Mouse Excisional Wound Model of Scarless HealingPlastic and Reconstructive Surgery, 117
T. Barker (2011)
The role of ECM proteins and protein fragments in guiding cell behavior in regenerative medicine.Biomaterials, 32 18
A. Mitrophanov, Sridevi Nagaraja, A. Wallqvist, J. Reifman (2014)
This information is current as of Chronic Wound Inflammation Causative Factors and Molecular Indicators Computational Approach To Characterize
R. Word (2010)
Medical and surgical therapy for advanced chronic venous insufficiency.The Surgical clinics of North America, 90 6
F. Fowkes, D. Rudan, I. Rudan, V. Aboyans, J. Denenberg, M. McDermott, P. Norman, Uchechukwe Sampson, Linda Williams, G. Mensah, M. Criqui (2013)
Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysisThe Lancet, 382
J. Reinke, H. Sorg (2012)
Wound Repair and RegenerationEuropean Surgical Research, 49
Dimitrios Baltzis, I. Eleftheriadou, A. Veves (2014)
Pathogenesis and Treatment of Impaired Wound Healing in Diabetes Mellitus: New InsightsAdvances in Therapy, 31
A. Stojadinovic, J. Carlson, G. Schultz, T. Davis, E. Elster (2008)
Topical advances in wound care.Gynecologic oncology, 111 2 Suppl
Marti-CarvajalA.J., SolaI., LathyrisD., CardonaA.F. (2012)
Human recombinant activated protein C for severe sepsisCochrane Database Syst. Rev., 3
M. Peppa, P. Stavroulakis, S. Raptis (2009)
Advanced glycoxidation products and impaired diabetic wound healingWound Repair and Regeneration, 17
M. Peschen, T. Lahaye, B. Hennig, A. Weyl, J. Simon, W. Vanscheidt (1999)
Expression of the adhesion molecules ICAM-1, VCAM-1, LFA-1 and VLA-4 in the skin is modulated in progressing stages of chronic venous insufficiency.Acta dermato-venereologica, 79 1
International Journal of Molecular Sciences – Unpaywall
Published: Dec 11, 2016
Access the full text.
Sign up today, get DeepDyve free for 14 days.