Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 7-Day Trial for You or Your Team.

Learn More →

Analysis of the experimental detection of central nervous system‐related genes in human brain and cerebrospinal fluid datasets

Analysis of the experimental detection of central nervous system‐related genes in human brain and... Large‐scale and high‐throughput proteomics experiments of specific samples provide substantial amounts of identified proteins and peptides, which increasingly find their way into centralized, public data repositories. These data typically have potential beyond the analyses performed by the original authors, and can therefore provide considerable added value by being reused for specific, unexplored enquiries. We here reanalyze two CNS‐related proteomics datasets, one from the HUPO's Brain Proteome Project, and one from a comprehensive analysis of cerebrospinal fluid in light of the expression of specific splice isoforms from CNS‐related genes. We also evaluate the empirically observed peptides of interest against predictions of their proteotypic character. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Proteomics Wiley

Analysis of the experimental detection of central nervous system‐related genes in human brain and cerebrospinal fluid datasets

Loading next page...
 
/lp/wiley/analysis-of-the-experimental-detection-of-central-nervous-system-pXax9w5BLA

References (34)

Publisher
Wiley
Copyright
"Copyright © 2008 Wiley Subscription Services, Inc., A Wiley Company"
ISSN
1615-9853
eISSN
1615-9861
DOI
10.1002/pmic.200700761
pmid
18283668
Publisher site
See Article on Publisher Site

Abstract

Large‐scale and high‐throughput proteomics experiments of specific samples provide substantial amounts of identified proteins and peptides, which increasingly find their way into centralized, public data repositories. These data typically have potential beyond the analyses performed by the original authors, and can therefore provide considerable added value by being reused for specific, unexplored enquiries. We here reanalyze two CNS‐related proteomics datasets, one from the HUPO's Brain Proteome Project, and one from a comprehensive analysis of cerebrospinal fluid in light of the expression of specific splice isoforms from CNS‐related genes. We also evaluate the empirically observed peptides of interest against predictions of their proteotypic character.

Journal

ProteomicsWiley

Published: Mar 1, 2008

Keywords: ; ; ; ;

There are no references for this article.