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Comparison of Anidulafungin MICs Determined by the Clinical and Laboratory Standards Institute Broth Microdilution Method (M27-A3 Document) and Etest for Candida Species Isolates

Comparison of Anidulafungin MICs Determined by the Clinical and Laboratory Standards Institute... Anidulafungin Etest and CLSI MICs were compared for 143 Candida sp. isolates to assess essential (within 2 log 2 dilutions) and categorical agreements (according to three susceptibility breakpoints). Based on agreement percentages, our data indicated that Etest is not suitable to test anidulafungin against Candida parapsilosis and C. guilliermondii (54.4 to 82.4% essential and categorical agreements) but is more suitable for C. albicans , C. glabrata , C. krusei , and C. tropicalis (87.9 to 100% categorical agreement). http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Antimicrobial Agents and Chemotherapy American Society For Microbiology

Comparison of Anidulafungin MICs Determined by the Clinical and Laboratory Standards Institute Broth Microdilution Method (M27-A3 Document) and Etest for Candida Species Isolates

Comparison of Anidulafungin MICs Determined by the Clinical and Laboratory Standards Institute Broth Microdilution Method (M27-A3 Document) and Etest for Candida Species Isolates

Antimicrobial Agents and Chemotherapy , Volume 54 (3): 1347 – Mar 1, 2010

Abstract

Anidulafungin Etest and CLSI MICs were compared for 143 Candida sp. isolates to assess essential (within 2 log 2 dilutions) and categorical agreements (according to three susceptibility breakpoints). Based on agreement percentages, our data indicated that Etest is not suitable to test anidulafungin against Candida parapsilosis and C. guilliermondii (54.4 to 82.4% essential and categorical agreements) but is more suitable for C. albicans , C. glabrata , C. krusei , and C. tropicalis (87.9 to 100% categorical agreement).

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References (36)

Publisher
American Society For Microbiology
Copyright
Copyright © 2010 by the American Society For Microbiology.
ISSN
0066-4804
eISSN
0066-4804
DOI
10.1128/AAC.01324-09
Publisher site
See Article on Publisher Site

Abstract

Anidulafungin Etest and CLSI MICs were compared for 143 Candida sp. isolates to assess essential (within 2 log 2 dilutions) and categorical agreements (according to three susceptibility breakpoints). Based on agreement percentages, our data indicated that Etest is not suitable to test anidulafungin against Candida parapsilosis and C. guilliermondii (54.4 to 82.4% essential and categorical agreements) but is more suitable for C. albicans , C. glabrata , C. krusei , and C. tropicalis (87.9 to 100% categorical agreement).

Journal

Antimicrobial Agents and ChemotherapyAmerican Society For Microbiology

Published: Mar 1, 2010

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