/lp/wiley/the-shortest-path-from-the-surface-to-the-nucleus-rbp-j-su-h-sWufIX4N9S
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- Publisher
- Wiley
- Copyright
- Blackwell Science Ltd, Oxford
- ISSN
- 1356-9597
- eISSN
- 1365-2443
- DOI
- 10.1046/j.1365-2443.1996.10010.x
- Publisher site
- See Article on Publisher Site
Abstract
Communication between cell surface receptors and nuclear transcription factors is of primary importance to multicellular organisms. Since there are numerous molecules involved in this process, their mutual interaction forms complex networks of informational regulation, which is still under extensive investigation. The RBP‐Jκ transcription factor interacts directly with the Notch receptor involved in cell lineage commitment, implicating the presence of a uniquely simple communication strategy between the surface receptor and the nucleus.
Journal
Genes to Cells – Wiley
Published: Jan 1, 1996