Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 7-Day Trial for You or Your Team.

Learn More →

Transmembrane Domain Peptide/Peptide Nucleic Acid Hybrid as a Model of a SNARE Protein in Vesicle Fusion

Transmembrane Domain Peptide/Peptide Nucleic Acid Hybrid as a Model of a SNARE Protein in Vesicle... Artificial models of the natural SNARE proteins containing the native linker regions (light blue/gray) and the transmembrane domains (TMDs) of synatobrevin (Syb, violet) and syntaxis‐1A (Sx, orange) along with a peptide nucleic acid (PNA) recognition motif can align with either an antiparallel (see picture) or parallel orientation of the interacting strands. These hybrids induce the hemifusion and partial bilayer fusion of phospholipid vesicles. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Angewandte Chemie International Edition Wiley

Transmembrane Domain Peptide/Peptide Nucleic Acid Hybrid as a Model of a SNARE Protein in Vesicle Fusion

Loading next page...
 
/lp/wiley/transmembrane-domain-peptide-peptide-nucleic-acid-hybrid-as-a-model-of-sjN2mBIx4z

References (28)

Publisher
Wiley
Copyright
Copyright © 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim
ISSN
1433-7851
eISSN
1521-3773
DOI
10.1002/anie.201101951
pmid
21786370
Publisher site
See Article on Publisher Site

Abstract

Artificial models of the natural SNARE proteins containing the native linker regions (light blue/gray) and the transmembrane domains (TMDs) of synatobrevin (Syb, violet) and syntaxis‐1A (Sx, orange) along with a peptide nucleic acid (PNA) recognition motif can align with either an antiparallel (see picture) or parallel orientation of the interacting strands. These hybrids induce the hemifusion and partial bilayer fusion of phospholipid vesicles.

Journal

Angewandte Chemie International EditionWiley

Published: Sep 5, 2011

There are no references for this article.